Hello! Describe your research question and I'll help you find matching datasets across 2,944 studies from AnVIL, BDC, CRDC, and KFDRC.

NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (MESA)

Anthropometry (3)

Biomarkers (19)

  • ESP_afib_baseline - Atrial fibrillation at baseline (0/1) (phv00178060.v1.p3)
  • ESP_avblock2_at_ekg - SECOND DEGREE AV BLOCK (phv00178089.v1.p3)
  • ESP_avblock3_at_ekg - THIRD DEGREE AV BLOCK (phv00178090.v1.p3)
  • ESP_crp - C-reactive protein level in mg/L at designated visit (may not be baseline) (phv00178069.v1.p3)
  • ESP_dbp_baseline - Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg (phv00178046.v1.p3)
  • ESP_ekg_hr - HR interval from EKG at designated visit (may not be baseline) (phv00178087.v1.p3)
  • ESP_ekg_pr - PR interval from EKG at designated visit (may not be baseline) (phv00178086.v1.p3)
  • ESP_ekg_qrs - QRS interval from EKG at designated visit (may not be baseline) (phv00178084.v1.p3)
  • ESP_ekg_qt - QT interval from EKG at designated visit (may not be baseline) (phv00178085.v1.p3)
  • ESP_hdl_baseline - HDL level in mg/dL at baseline (phv00178041.v1.p3)
  • ESP_icam1 - ICAM1 level in ng/mL at designated visit (may not be baseline) (phv00178071.v1.p3)
  • ESP_ldl_baseline - Baseline calculated LDL in mg/dL (missing where trigs>400) (phv00178040.v1.p3)
  • ESP_sbp_baseline - Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg (phv00178045.v1.p3)
  • ESP_serum_creatinine - Serum creatinine in mg/dL (phv00178103.v1.p3)
  • ESP_serum_cystatinc - Raw cystatin C (mg/L) (phv00178101.v1.p3)
  • ESP_totchol_baseline - Total cholesterol at baseline in mg/dL (phv00178043.v1.p3)
  • ESP_trigs_baseline - Triglycerides at baseline in mg/dL (phv00178042.v1.p3)
  • ESP_urinary_albumin - Raw urinary albumin. Note: these are in original study units and not harmonized across studies) (phv00178097.v1.p3)
  • ESP_urinary_creatinine - Raw urinary creatinine in mg/dL (phv00178099.v1.p3)

Demographics (16)

Disease Events (10)

  • ESP_angioplasty_baseline - BASELINE ANGIOPLASTY STATUS (0/1) (phv00178079.v1.p3)
  • ESP_asthma_ever - Asthma ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00178106.v1.p3)
  • ESP_cabg_baseline - BASELINE CABG STATUS (0/1) (phv00178080.v1.p3)
  • ESP_emphysema_ever - Emphysema ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00178107.v1.p3)
  • ESP_gout - May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study. (phv00178105.v1.p3)
  • ESP_mi_baseline - MI status at baseline (0/1) (phv00178029.v1.p3)
  • ESP_mi_during_followup - 0/1 to indicate that an MI occurred during study follow up. 0 if no MI during study follow up. 1 if an adjudicated MI occurred during study follow up (even if baseline MI status was 1). (phv00178030.v1.p3)
  • ESP_pad - BASELINE PERIPHERAL ARTERY DISEASE STATUS (0/1) (phv00178081.v1.p3)
  • ESP_stroke_famhx_baseline - Family history (first degree relatives) of stroke at baseline (0/1) (phv00178053.v1.p3)
  • ESP_t2diabetes_baseline - Diabetes status at baseline (0/1) (phv00178034.v1.p3)

Geography (1)

  • ESP_study_site_or_subcohort - Clinic or field center within cohort (phv00178027.v1.p3)

Imaging (4)

  • ESP_cac_agatston_score - Coronary artery calcium Agatston total score (phv00178073.v1.p3)
  • ESP_imt_anyplaque - Presence of any plaque, as determined by IMT at designated visit (may not be baseline). (phv00178077.v1.p3)
  • ESP_imt_meanmean_farwall_cca - Average far wall thickness of the right and left common carotid mean IMT values, using as many views as are available for a given study (phv00178075.v1.p3)
  • ESP_imt_meanmean_farwall_ica - Average far wall thickness of the right and left internal carotid maximum IMT values, using as many views as are available for a given study (phv00178076.v1.p3)

Medications (3)

  • ESP_htn_med_baseline - Hypertension med status (any) at baseline (0/1) (phv00178048.v1.p3)
  • ESP_lipid_med_baseline - Any lipid lowering med (statin or other) at baseline (phv00178044.v1.p3)
  • ESP_t2d_med_baseline - Baseline Type 2 diabetes medication status (0/1) (phv00178035.v1.p3)

Race and Ethnicity (1)

Reproductive Health (3)

  • ESP_hormone_replacement_baseline - Indicator (0/1) for current use of hormone replacement therapy (phv00178059.v1.p3)
  • ESP_menopause_status_baseline - BASELINE MENOPAUSE STATUS (phv00178056.v1.p3)
  • ESP_surgical_menopause - Indicator (0/1) for surgically induced menopause (phv00178058.v1.p3)

Respiratory (2)

  • ESP_fev1_first_avail_visit - FEV1 measurement at the first available visit (only for HeartGO) (phv00178108.v1.p3)
  • ESP_fvc_first_avail_visit - FVC measurement at the first available visit (only for HeartGO) (phv00178109.v1.p3)

Substance Use (2)

  • ESP_current_smoker_baseline - Current smoking status at baseline (0/1) (phv00178054.v1.p3)
  • ESP_former_smoker_baseline - Former smoking status at baseline (0/1) (phv00178055.v1.p3)

Other (33)

  • Analyte_type - Type of analyte (phv00178115.v1.p3)
  • Body_site - Body site or tissue that sample is from (phv00178114.v1.p3)
  • ESP_ABI_resids_from_CARe - Residuals for ankle brachial index (ABI), calculated in CARe (phv00178082.v1.p3)
  • ESP_beta_blockers_ekg - Betablockers, for EKG group. (phv00178095.v1.p3)
  • ESP_Cohort - Cohort name (phv00178021.v1.p3)
  • ESP_digoxin_ekg - Digoxin, for EKG group (phv00178092.v1.p3)
  • ESP_dihydro_calc_chan_block - Dihydropyridine calcium channel blockers (phv00178093.v1.p3)
  • ESP_factorviii - Factor VIII level in % at designated visit (may not be baseline) (phv00178065.v1.p3)
  • ESP_fastglucose_baseline - Blood fasting insulin at baseline in uU/mL. (Note that there are some extreme outliers) (phv00178061.v1.p3)
  • ESP_fastinsulin_baseline - Blood fasting glucose at baseline in mg/dL (phv00178062.v1.p3)
  • ESP_fibrinogen - Fibrinogen level in mg/dL at first designated visit (may not be baseline) (phv00178063.v1.p3)
  • ESP_frs_chdprob_baseline - Framingham Risk Score predicted prob. calculated at baseline (was not calculated for those with baseline history of MI) (phv00178032.v1.p3)
  • ESP_htn_status_baseline - Physician diagnosed hypertension status at baseline (0/1) (phv00178047.v1.p3)
  • ESP_inc_stroke_subtype - Incident stroke subtype. Subtype is available only on a subset of samples, so will be missing for some with non-missing age at incident stroke (phv00178052.v1.p3)
  • ESP_lung_function_visit - The visit that lung function measurements were taken (phv00178110.v1.p3)
  • ESP_mi_tte_or_censor - Time to event variable for MI. Time (in days) from start of study to MI for event that occurred during study follow up; and follow up time for those that did not have an MI during study follow up. (phv00178031.v1.p3)
  • ESP_nondihydro_calc_chan_block - Non-dihydropyridine calcium channel blockers, for EKG group. (phv00178094.v1.p3)
  • ESP_pacer_ekg - PACER AT EKG (phv00178091.v1.p3)
  • ESP_phenotype - ESP Phenotype group (phenotype that the sample was selected to be sequenced for) (phv00178022.v1.p3)
  • ESP_phenotype - ESP Phenotype group (phenotype that the sample was selected to be sequenced for) (phv00178113.v1.p3)
  • ESP_stroke_baseline - Stroke status at baseline (0/1) (phv00178049.v1.p3)
  • ESP_stroke_during_followup - 0/1 to indicate that a stroke occurred during study follow up. 0 if no stroke during study follow up. 1 if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1). (phv00178050.v1.p3)
  • ESP_stroke_tte_or_censor - Time to event variable for stroke. Time (in days) from start of study to stroke for event that occurred during study follow up; and follow up time for those that did not have an stroke during study follow up. (phv00178051.v1.p3)
  • ESP_vwf - VWF level in % at designated visit (may not be baseline) (phv00178067.v1.p3)
  • ESP_waist_baseline - Waist in cm at baseline (phv00178037.v1.p3)
  • ESP_whr_baseline - Waist to hip ratio at baseline (phv00178038.v1.p3)
  • ESP_wpw_at_ekg - WOLFF-PARKINSON-WHITE PATTERN (phv00178088.v1.p3)
  • ESP6800vcf_id - Sample ID for the ESP6800 vcf file (phv00178112.v1.p3)
  • Is_tumor - Indicator of whether sample from tumor (phv00178116.v1.p3)
  • SAMPID - Sample ID (for individual vcf files from sequencing sites) (phv00178111.v1.p3)
  • Sequence_center - Indicates where the sample was sequence at (phv00178023.v1.p3)
  • SUBJID - Subject ID (phv00178020.v1.p3)
  • Target - Indicates target capture used in sequencing (phv00178024.v1.p3)