A Genome-Wide Association Study of Fuchs' Endothelial Corneal Dystrophy (FECD)

Request Access

Demographics (7)

age - Age at Assessment (phv00181938.v1.p1)
previous_cat_od_age - Age of OD Cataract Surgery (phv00181953.v1.p1)
previous_cat_os_age - Age of OS Cataract Surgery (phv00181955.v1.p1)
previous_pk_od_age - Age of OD surgery (phv00181948.v1.p1)
previous_pk_os_age - Age of OS surgery (phv00181950.v1.p1)
sex - Sex of participant (phv00181939.v1.p1)
SEX - Subject's sex (phv00181929.v1.p1)

Disease Events (2)

diagnosis_other - Has the diagnosis of other corneal dystrophies ever been made? (phv00181944.v1.p1)
family_history_fecd - Does the participant have any relatives with a history of FECD or other corneal dystrophies? (phv00181945.v1.p1)

General Health (45)

cornea_end_gut_od - If OD endothelium is abnormal, guttae? (phv00181971.v1.p1)
cornea_end_gut_os - If OS endothelium is abnormal, guttae? (phv00181992.v1.p1)
cornea_end_ker_od - If OD endothelium is abnormal, keratoprecipitates? (phv00181972.v1.p1)
cornea_end_ker_os - If OS endothelium is abnormal, keratoprecipitates? (phv00181993.v1.p1)
cornea_end_kru_od - If OD endothelium is abnormal, Krukenberg spindle? (phv00181973.v1.p1)
cornea_end_kru_os - If OS endothelium is abnormal, Krukenberg spindle? (phv00181994.v1.p1)
cornea_end_norm_od - If OD cornea is abnormal, is the Descemet's/Endothelium normal? (phv00181970.v1.p1)
cornea_end_norm_os - If OS cornea is abnormal, is the endothelium normal? (phv00181991.v1.p1)
cornea_end_pig_od - If OD endothelium is abnormal, pigments? (phv00181974.v1.p1)
cornea_end_pig_os - If OS endothelium is abnormal, pigment? (phv00181995.v1.p1)
cornea_end_ves_od - If OD endothelium is abnormal, vesicles? (phv00181975.v1.p1)
cornea_end_ves_os - If OS endothelium is abnormal, vesicles? (phv00181996.v1.p1)
cornea_epi_dys_od - If OD epithelium is abnormal, dystrophy (e.g. map-dot-fingerprint)? (phv00181958.v1.p1)
cornea_epi_dys_os - If OS epithelium is abnormal, dystrophy (e.g. map-dot-fingerprint)? (phv00181979.v1.p1)
cornea_epi_ede_od - If OD epithelium is abnormal, edema? (phv00181959.v1.p1)
cornea_epi_ede_os - If OS epithelium is abnormal, edema? (phv00181980.v1.p1)
cornea_epi_inf_od - If OD epithelium is abnormal, infiltrates? (phv00181960.v1.p1)
cornea_epi_inf_os - If OS epithelium is abnormal, infiltrates? (phv00181981.v1.p1)
cornea_epi_norm_od - If OD cornea is abnormal, is the epithelium normal? (phv00181957.v1.p1)
cornea_epi_norm_os - If OS cornea is abnormal, is the epithelium normal? (phv00181978.v1.p1)
cornea_epi_vas_od - If OD epithelium is abnormal, vascularization? (phv00181961.v1.p1)
cornea_epi_vas_os - If OS epithelium is abnormal, vascularization? (phv00181982.v1.p1)
cornea_normal_od - Is the OD cornea normal? (phv00181956.v1.p1)
cornea_normal_os - Is the OS cornea normal? (phv00181977.v1.p1)
cornea_str_dys_od - If OD stroma is abnormal, dystrophy (e.g. granular)? (phv00181964.v1.p1)
cornea_str_dys_os - If OS stroma is abnormal, dystrophy (e.g. granular)? (phv00181985.v1.p1)
cornea_str_ede_od - If OD stroma is abnormal, edema? (phv00181965.v1.p1)
cornea_str_ede_os - If OS stroma is abnormal, edema? (phv00181986.v1.p1)
cornea_str_inf_od - If OD stroma is abnormal, infiltrates? (phv00181966.v1.p1)
cornea_str_inf_os - If OS stroma is abnormal, infiltrates? (phv00181987.v1.p1)
cornea_str_norm_od - If OD cornea is abnormal, is the stroma normal? (phv00181963.v1.p1)
cornea_str_norm_os - If OS cornea is abnormal, is the stroma normal? (phv00181984.v1.p1)
cornea_str_sca_od - If OD stroma is abnormal, scarring? (phv00181967.v1.p1)
cornea_str_sca_os - If OS stroma is abnormal, scarring? (phv00181988.v1.p1)
cornea_str_vas_od - If OD stroma is abnormal, vascularization? (phv00181968.v1.p1)
cornea_str_vas_os - If OS stroma is abnormal, vascularization? (phv00181989.v1.p1)
diagnosis_fecd - Has a diagnosis of FECD ever been made? (phv00181942.v1.p1)
fecd_grading_od - FECD Consortium Grade OD (oculus dexter) (phv00182000.v1.p1)
fecd_grading_os - FECD Consortium Grade OS (oculus sinister) (phv00182001.v1.p1)
previous_cat_od - OD Cataract Surgery? (phv00181952.v1.p1)
previous_cat_os - OS Cataract Surgery? (phv00181954.v1.p1)
previous_cat_surgery - Has the participant had any previous cataract surgery? (corneal or glaucoma surgery/laser eyes are excluded) (phv00181951.v1.p1)
previous_pk_od - Penetrating Keratoplasty or DSEK in OD (phv00181947.v1.p1)
previous_pk_os - Penetrating Keratoplasty or DSEK in OS (phv00181949.v1.p1)
previous_pk_surgery - Has the participant had any previous keratoplasty? (phv00181946.v1.p1)

Race and Ethnicity (1)

race - Racial Category (phv00181940.v1.p1)

Other (34)

ANALYTE_TYPE - Analyte type (phv00182007.v1.p1)
BODY_SITE - Body site where sample was collected (phv00182006.v1.p1)
CONSENT - Consent group as determined by DAC (phv00181922.v1.p1)
cornea_end_other_od - If OD endothelium is abnormal, are there any other abnormalities? Please specify: (phv00181976.v1.p1)
cornea_end_other_os - If OS endothelium is abnormal, are there any other abnormalities? Please specify: (phv00181997.v1.p1)
cornea_epi_other_od - If OD epithelium is abnormal, are there any other abnormalities? Please specify: (phv00181962.v1.p1)
cornea_epi_other_os - If OS epithelium is abnormal, are there any other abnormalities? Please specify: (phv00181983.v1.p1)
cornea_str_other_od - If OD stroma is abnormal, are there any other abnormalities? Please specify: (phv00181969.v1.p1)
cornea_str_other_os - If OS stroma is abnormal, are there any other abnormalities? Please specify: (phv00181990.v1.p1)
diagnosis_fecd_when - If yes (diagnosis of FECD), when was the diagnosis made? (phv00181943.v1.p1)
FAMID - Family ID (phv00181925.v1.p1)
FATHER - Father ID (phv00181927.v1.p1)
fecd_grading_time - Time of FECD Grading? (phv00181998.v1.p1)
fecd_grading_time_meridiem - AM or PM (time of FECD Grading) (phv00181999.v1.p1)
HISTOLOGICAL_TYPE - Cell or tissue type or subtype of sample (phv00182008.v1.p1)
IS_TUMOR - Tumor status (phv00182009.v1.p1)
MOTHER - Mother ID (phv00181928.v1.p1)
pathology_obtained - Was a pathology specimen obtained for this participant? (phv00182002.v1.p1)
pathology_result - Were finding definitely FECD or consistent with FECD? (phv00182004.v1.p1)
pathology_type - If yes, what type of specimen was obtained? (phv00182003.v1.p1)
PED.NOTE - PED note regarding subject (phv00181930.v1.p1)
race_other - If other race, please describe (phv00181941.v1.p1)
SAMP_SOURCE - Source repository of samples (phv00181934.v1.p1)
SAMPID - Sample ID (phv00181933.v1.p1)
SAMPID - De-identified Sample ID (phv00182005.v1.p1)
SAMPLE_USE - Sample Use (phv00181936.v1.p1)
SOURCE_SAMPID - Sample ID used at the source repository (phv00181935.v1.p1)
SOURCE_SUBJID - Subject ID used in the Source Repository (phv00181924.v1.p1)
SUBJ_SOURCE - Source repository where subjects originate (phv00181923.v1.p1)
SUBJID - Subject Id (phv00181937.v1.p1)
SUBJID - Subject ID (phv00181926.v1.p1)
SUBJID - Subject ID (phv00181932.v1.p1)
SUBJID - Subject ID (phv00181921.v1.p1)
SUPERFAMILY - Superfamily ID (phv00181931.v1.p1)