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Genome and Targeted Sequencing of Bladder Cancer

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The landscape of somatic copy-number alteration across human cancers

R. Beroukhim, C. Mermel, D. Porter, et al. (2010). Nature. Cited 3,789 times. https://doi.org/10.1038/nature08822

The tuberous sclerosis complex.

Peter B Crino, K. Nathanson, E. Henske. (2006). The New England journal of medicine. Cited 964 times. https://doi.org/10.1056/NEJMRA055323

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

Andrew R. Tee, D. Fingar, B. Manning, et al. (2002). Proceedings of the National Academy of Sciences of the United States of America. Cited 845 times. https://doi.org/10.1073/pnas.202476899

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR.

Hongbing Zhang, G. Cicchetti, H. Onda, et al. (2003). The Journal of clinical investigation. Cited 557 times. https://doi.org/10.1172/JCI17222

Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.

D. Krueger, Marguerite M. Care, Katherine Holland, et al. (2010). The New England journal of medicine. Cited 468 times. https://doi.org/10.1056/NEJMoa1001671