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Methotrexate Clearance GWAS

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Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study.

M. Borowitz, M. Devidas, S. Hunger, et al. (2008). Blood. Cited 498 times. https://doi.org/10.1182/blood-2008-01-132837

Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.

L. Treviño, N. Shimasaki, Wenjian Yang, et al. (2009). Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Cited 329 times. https://doi.org/10.1200/JCO.2008.20.4156

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition.

L. Ramsey, G. H. Bruun, Wenjian Yang, et al. (2012). Genome research. Cited 262 times. https://doi.org/10.1101/gr.129668.111

Genome-wide study of methotrexate clearance replicates SLCO1B1.

L. Ramsey, J. Panetta, Colton A. Smith, et al. (2013). Blood. Cited 192 times. https://doi.org/10.1182/blood-2012-08-452839