National Institute of Dental and Craniofacial Research (NIDCR) Sjögren's International Collaborative Clinical Alliance (SICCA): Center for Inherited Disease Research (CIDR) Genome-Wide Genotyping

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Demographics (4)

age_censored - Censored age at study visit with ages > 89 changed to 89 (phv00226941.v1.p1)
agess - Self reported Age of Sjögren's syndrome onset at screening (phv00226852.v1.p1)
Sex - Gender of participant (phv00226846.v1.p1)
SEX - Subject's sex (phv00226838.v1.p1)

Disease Events (26)

ana - Antinuclear Antibody (ANA) result (phv00226858.v1.p1)
anatiter - Antinuclear Antibody Titer result (phv00226859.v1.p1)
antihepc - Anti-Hepatitis C result (phv00226863.v1.p1)
c3 - Complement Component 3 (C3) result (phv00226861.v1.p1)
c4 - Complement Component 4 (C4) result (phv00226862.v1.p1)
dryeye - Dry eye symptoms (phv00226885.v1.p1)
drymouth - Dry mouth symptoms (phv00226883.v1.p1)
igg - Immunoglobulin G (IgG) result (phv00226860.v1.p1)
kidney - Physician confirmed Kidney disease (phv00226914.v1.p1)
liver - Physician confirmed Liver disease (phv00226913.v1.p1)
lymphoma - Physician confirmed Lymphoma (phv00226915.v1.p1)
ra - Physician confirmed Rheumatoid Arthritis (phv00226904.v1.p1)
rf - Rheumatoid Factor result (phv00226857.v1.p1)
self_aorild - Self reported Autoimmune or Interstitial Lung disease (phv00226911.v1.p1)
self_kid - Self reported Kidney disease (phv00226909.v1.p1)
self_liv - Self reported Liver disease (phv00226908.v1.p1)
self_lymph - Self reported Lymphoma (phv00226910.v1.p1)
self_ra - Self reported Rheumatoid Arthritis (phv00226902.v1.p1)
self_sle - Self reported Systemic Lupus Erythematosus (phv00226903.v1.p1)
self_thy - Self reported Thyroid disease (phv00226907.v1.p1)
sle - Physician confirmed Systemic Lupus Erythematosus (phv00226905.v1.p1)
ssa - Anti-SS-A result (phv00226853.v1.p1)
ssab - Result of Anti-SS-A or Anti-SS-B (phv00226855.v1.p1)
ssanb - Result of Anti-SS-A and Anti-SS-B (phv00226856.v1.p1)
ssb - Anti-SS-B result (phv00226854.v1.p1)
thyroid - Physician confirmed Thyroid disease (phv00226912.v1.p1)

Geography (1)

site - Recruitment site (phv00226849.v1.p1)

Mental Health (13)

depscore - PHQ-9 Depression Severity (phv00226882.v1.p1)
sf12v2_1 - SF-12v2 Health Survey - General Health (phv00226890.v1.p1)
sf12v2_10 - SF-12v2 Health Survey - Have a lot of energy in past 4 weeks (phv00226899.v1.p1)
sf12v2_11 - SF-12v2 Health Survey - Felt downhearted and depressed in past 4 weeks (phv00226900.v1.p1)
sf12v2_12 - SF-12v2 Health Survey - How much physical or emotional health interfered with social activities in past 4 weeks (phv00226901.v1.p1)
sf12v2_2 - SF-12v2 Health Survey - Health limits moderate activities (phv00226891.v1.p1)
sf12v2_3 - SF-12v2 Health Survey - Health limits climbing stairs (phv00226892.v1.p1)
sf12v2_4 - SF-12v2 Health Survey - Accomplished less as result of physical health in past 4 weeks (phv00226893.v1.p1)
sf12v2_5 - SF-12v2 Health Survey - Physical health limited kind of work in past 4 weeks (phv00226894.v1.p1)
sf12v2_6 - SF-12v2 Health Survey - Accomplished less as result of emotional problems in past 4 weeks (phv00226895.v1.p1)
sf12v2_7 - SF-12v2 Health Survey - Did work less carefully than usual as result of emotional problems in past 4 weeks (phv00226896.v1.p1)
sf12v2_8 - SF-12v2 Health Survey - How much pain interfered with normal work in past 4 weeks (phv00226897.v1.p1)
sf12v2_9 - SF-12v2 Health Survey - Felt calm and peaceful in past 4 weeks (phv00226898.v1.p1)

Race and Ethnicity (23)

eth2_c_am - Grandparents Origin - Central American (phv00226928.v1.p1)
eth2_c_eu - Grandparents Origin - Central European (phv00226918.v1.p1)
eth2_ca - Grandparents Origin - Caribbean (phv00226929.v1.p1)
eth2_ch_h - Grandparents Origin - Chinese Han (phv00226932.v1.p1)
eth2_ch_n - Grandparents Origin - Chinese Non-Han (phv00226933.v1.p1)
eth2_e_eu - Grandparents Origin - Eastern European (phv00226920.v1.p1)
eth2_e_me - Grandparents Origin - East Mediterranean (phv00226922.v1.p1)
eth2_fi - Grandparents Origin - Filipino (phv00226936.v1.p1)
eth2_in - Grandparents Origin - Indian sub-continent (phv00226938.v1.p1)
eth2_ja - Grandparents Origin - Japanese (phv00226934.v1.p1)
eth2_ko - Grandparents Origin - Korean (phv00226935.v1.p1)
eth2_l_in - Grandparents Origin - Latin American Indian (phv00226931.v1.p1)
eth2_m_ea - Grandparents Origin - Middle Eastern (phv00226921.v1.p1)
eth2_me - Grandparents Origin - Mexican (phv00226927.v1.p1)
eth2_n_af - Grandparents Origin - North African (phv00226923.v1.p1)
eth2_n_am - Grandparents Origin - North American (phv00226925.v1.p1)
eth2_n_eu - Grandparents Origin - Northern European (phv00226917.v1.p1)
eth2_n_in - Grandparents Origin - North American Indian (phv00226926.v1.p1)
eth2_s_af - Grandparents Origin - Subsaharan African (phv00226924.v1.p1)
eth2_s_am - Grandparents Origin - South American (phv00226930.v1.p1)
eth2_s_as - Grandparents Origin - South-East Asian (phv00226937.v1.p1)
eth2_s_eu - Grandparents Origin - Southern European (phv00226919.v1.p1)
race - Self-reported ethnicity of participant (phv00226851.v1.p1)

Substance Use (2)

cigday - Cigarettes smoked per day (phv00226881.v1.p1)
smoker - Cigarette use (phv00226880.v1.p1)

Other (49)

aecg - Meets American European classification for primary Sjögren's Syndrome (phv00226889.v1.p1)
ANALYTE_TYPE - Analyte Type (phv00226945.v1.p1)
antichol - Anticholinergic drug use (phv00226888.v1.p1)
arttears - How often artificial tears used (phv00226886.v1.p1)
BODY_SITE - Body site where sample was collected (phv00226944.v1.p1)
collection_phase - 2 different sets of subjects genotyped in 2011 and 2013. The marker set versions for the phases are different. (phv00226847.v1.p1)
CONSENT - Consent (phv00226831.v1.p1)
eth2_oth - Grandparents Origin - Other (phv00226939.v1.p1)
FAMILY_ID - Family ID (phv00226834.v1.p1)
famstatus - Family Status (phv00226848.v1.p1)
FATHER - Father ID (phv00226836.v1.p1)
focus - Focus score (phv00226870.v1.p1)
fs - Focus score >=1 (phv00226871.v1.p1)
fscalc - Labial Salivary gland large enough to support focus score calculation (phv00226869.v1.p1)
griteye - Gritty or scratchy sensation in eye during last week (phv00226887.v1.p1)
HISTOLOGICAL_TYPE - Cell or tissue type or subtype of sample (phv00226946.v1.p1)
IS_TUMOR - Tumor status (phv00226947.v1.p1)
liqmouth - Need liquids for swallowing (phv00226884.v1.p1)
lparenlg - Left Parotid Gland enlargement (phv00226867.v1.p1)
lsgdx - Labial Salivary Gland biopsy diagnosis (phv00226868.v1.p1)
MOTHER - Mother ID (phv00226837.v1.p1)
oss - Max Ocular SICCA score >= 3 (phv00226874.v1.p1)
ossl - Ocular SICCA score - left eye (phv00226873.v1.p1)
ossr - Ocular SICCA score - right eye (phv00226872.v1.p1)
otherctd - Physician confirmed Scleroderma or Other Connective Tissue disease (phv00226906.v1.p1)
othersys - Physician confirmed Other Systemic disease (phv00226916.v1.p1)
ptstatus - Participation status (phv00226850.v1.p1)
rparenlg - Right Parotid Gland enlargement (phv00226866.v1.p1)
SAMPLE_ID - Sample ID (phv00226841.v1.p1)
SAMPLE_ID - De-identified sample ID (phv00226943.v1.p1)
SAMPLE_SOURCE - Coriell for HapMap samples, source repository for investigator controls, blank otherwise. (phv00226843.v1.p1)
SAMPLE_USE - Sample Use. Array_SNP: SNP genotypes obtained using standard or custom microarrays; Imputation_SNP: Imputed SNP genotypes (phv00226842.v1.p1)
sch - Mean of Schirmer1 test <= 5 mm in 5 minutes (phv00226879.v1.p1)
SOURCE_SAMPLE_ID - Coriell ID for HapMap samples, repository ID for investigator controls, blank otherwise. (phv00226844.v1.p1)
SOURCE_SUBJECT_ID - Coriell ID for HapMap subjects, repository ID for investigator controls, blank otherwise. (phv00226833.v1.p1)
sscase - Meets American College of Rheumatology classification criteria for Sjögren's syndrome 2012 (see: <a href="http://www.ncbi.nlm.nih.gov/pubmed/22563590">PMID: 22563590</a>) (phv00226940.v1.p1)
SUBJECT_ID - De-identified Subject ID (phv00226845.v1.p1)
SUBJECT_ID - Subject ID (phv00226835.v1.p1)
SUBJECT_ID - Subject ID (phv00226840.v1.p1)
SUBJECT_ID - Subject ID (phv00226830.v1.p1)
SUBJECT_SOURCE - Coriell for HapMap subjects, source repository for investigator controls, blank otherwise. (phv00226832.v1.p1)
subjecttype - Study subject type, with Sjögren's Syndrome classification according to <a href="http://www.ncbi.nlm.nih.gov/pubmed/22563590">2012 American College of Rheumatology</a> criteria (phv00226942.v1.p1)
tbul - Tear Break-Up time - left eye >= 10 seconds (phv00226876.v1.p1)
tbul_time - Tear Break-Up Time - left eye if less than 10 seconds (phv00226878.v1.p1)
tbur - Tear Break-Up time - right eye >= 10 seconds (phv00226875.v1.p1)
tbur_time - Tear Break-Up time - right eye if less than 10 seconds (phv00226877.v1.p1)
TWIN_ID - Subjects are twins (phv00226839.v1.p1)
uws - Unstimulated whole salivary flow rate (phv00226864.v1.p1)
uwslt5 - Unstimulated whole salivary flow rate < 0.5 ml/5 min (phv00226865.v1.p1)