Genome-Wide Association Study of Adiposity in Samoans

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Anthropometry (12)

BIA_BF - Percent Body Fat based on Bioelectrical Impedance (BIA). Polynesian-specific equations: Swinburn et al., 1999 & Keighley et al., 2006 (phv00258779.v1.p1)
BMI - Body mass index of participant (phv00258685.v1.p1)
BMI_BF - Percent Body Fat based on Body Mass Index. Polynesian-specific equations: Swinburn et al., 1999 (phv00258781.v1.p1)
Height - Height of participant (phv00258683.v1.p1)
Obesity_Int - Obesity Classification using International Cutoffs (STEPS) (phv00258686.v1.p1)
Obesity_Poly - Obesity Classification using Polynesian Cutoffs (phv00258687.v1.p1)
OWOB_Binary_Poly - Obese or Overweight using Polynesian Cutoffs (phv00258688.v1.p1)
SKF_BF - Percent Body Fat based on Skinfold Measurements. Polynesian-specific equations: Swinburn et al., 1999 (phv00258780.v1.p1)
Sub_Skf - Subscapular Skinfold (Average) (phv00258695.v1.p1)
Sup_Skf - Suprailiac Skinfold (Average) (phv00258697.v1.p1)
Tri_Skf - Triceps Skinfold (Average) (phv00258693.v1.p1)
Weight - Weight of participant (phv00258684.v1.p1)

Biomarkers (23)

Adiponectin - Adiponectin from venous blood sample (phv00258732.v1.p1)
Cholesterol - Cholesterol from venous blood sample (mg/dL) (phv00258733.v1.p1)
Cholesterol_mmol - Cholesterol from venous blood sample (mmol) (phv00258734.v1.p1)
Diastolic_BP - Diastolic blood pressure (average of last two measurements) (phv00258703.v1.p1)
Diastolic_BP_Av3 - Diastolic blood pressure (average of all three measurements) (phv00258704.v1.p1)
Finger_Glucose - Blood Glucose from finger stick assessment (phv00258727.v1.p1)
Glucose - Glucose from venous blood sample (phv00258730.v1.p1)
HDL_Binary - HDL cholesterol below or equal to (1) or above (0) 1.03 mmol/l (men) or 1.29 mmol/l (women) (AHA criteria) (phv00258745.v1.p1)
HDL_C - HDL-C from venous blood sample (mg/dL) (phv00258743.v1.p1)
HDL_mmol - HDL-C from venous blood sample (mmol) (phv00258744.v1.p1)
Heart_Rate - Heart Rate (measured during blood pressure assessment) (Average) (phv00258724.v1.p1)
Insulin - Insulin from venous blood sample (phv00258729.v1.p1)
LDL_Binary - LDL cholesterol above or equal to (1) or below (0) 2.59 mmol/l (AHA criteria) (phv00258742.v1.p1)
LDL_C - LDL-C from venous blood sample (mg/dL) (phv00258740.v1.p1)
LDL_mmol - LDL-C from venous blood sample (mmol) (phv00258741.v1.p1)
Leptin - Leptin from venous blood sample (phv00258731.v1.p1)
NetTG - Net Triglycerides from venous blood sample (mg/dL) (phv00258736.v1.p1)
Systolic_BP - Systolic blood pressure (average of last two measurements) (phv00258701.v1.p1)
Systolic_BP_Av3 - Systolic blood pressure (average of all three measurements) (phv00258702.v1.p1)
Total_Cholesterol_Binary - Total cholesterol above or equal to (1) or below (0) 5.2 mmol/l (AHA criteria) (phv00258735.v1.p1)
Triglycerides_Binary - Triglycerides above (1) or below or equal to (0) 1.69 mmol/l (AHA criteria) (phv00258738.v1.p1)
Triglycerides_mmol - Net Triglycerides from venous blood sample (mmol) (phv00258737.v1.p1)
VLDL_C - VLDL-C from venous blood sample (phv00258739.v1.p1)

Demographics (8)

Age_Quit - Age Quit Smoking (phv00258714.v1.p1)
Age_smoking - Age Started Smoking (years) (phv00258706.v1.p1)
Gender - Gender of participant (phv00258679.v1.p1)
Length_Quit_Months - Length of time since Quitting (months) (phv00258716.v1.p1)
Length_Quit_Weeks - Length of time since Quitting (weeks) (phv00258717.v1.p1)
Length_Quit_Years - Length of time since Quitting (years) (phv00258715.v1.p1)
Length_sm_months - Length of time smoking (months) (phv00258708.v1.p1)
Length_sm_years - Length of time smoking (years) (phv00258707.v1.p1)

Disease Events (14)

Angina - Angina diagnosis - Self-report (phv00258766.v1.p1)
Diabetes_Binary - Diabetes Status (based on venous blood sample and questionnaire data) (phv00258759.v1.p1)
Diabetes_diagnosis - Have you ever been diagnosed with diabetes? (Based on questionnaire) (phv00258760.v1.p1)
Diabetes_diagnosis_years - How many years ago were you diagnosed with diabetes? (phv00258761.v1.p1)
Diabetes_Status - Diabetes Status (based on venous blood sample ONLY) (phv00258758.v1.p1)
Hd_diagnosis_years - How many years ago were you diagnosed with heart disease? (phv00258770.v1.p1)
Heart_attack - Have you ever had a heart attack? Self-report (phv00258767.v1.p1)
Heart_disease_diagnosis - Have you ever been diagnosed with heart disease? (Based on questionnaire) (phv00258769.v1.p1)
Hyp_diagnosis_years - How many years ago were you diagnosed with hypertension? (phv00258748.v1.p1)
Hypertension - Based on Sys>140 OR Dias>90 (Based on physical examination & questionnaire data) (phv00258746.v1.p1)
Hypertension_13 - Hypertension based on average of two BP measurements or hypertension meds (phv00258756.v1.p1)
Hypertension_All3 - Hypertension diagnosis based on average of all three BP measurements or hypertension meds (phv00258757.v1.p1)
Hypertension_diagnosis - Self-reported Hypertension diagnosis (phv00258747.v1.p1)
Stroke - Have you ever had a stroke? Self-report (phv00258768.v1.p1)

Exercise (25)

Percent_LeisureMVPA - Percentage of physical activity completed in leisure time activities (phv00258835.v1.p1)
Percent_TransportMVPA - Percentage of physical activity completed in transport activities (walking/cycling) (phv00258834.v1.p1)
Percent_WorkMVPA - Percentage of physical activity completed in work-related activities (phv00258833.v1.p1)
Sitting_Hours - Hours spent sitting during a typical day (phv00258805.v1.p1)
Sitting_Mins - Minutes spent sitting during a typical day (phv00258806.v1.p1)
Total_MET_Week - Total MET value for all weekly activity (phv00258818.v1.p1)
TypicalDaily_LeisureModerateMins - Minutes of moderate leisure time activity (on a typical day) (phv00258811.v1.p1)
TypicalDaily_LeisureVigorousMins - Minutes of vigorous leisure time activity (on a typical day) (phv00258810.v1.p1)
TypicalDaily_SittingMins - Minutes of sitting/reclining (on a typical day) (phv00258812.v1.p1)
TypicalDaily_TransportMins - Minutes of Walking/Cycling (on a typical day) (phv00258809.v1.p1)
TypicalDaily_WorkModerateMins - Minutes of moderate work activity (on a typical day) (phv00258808.v1.p1)
TypicalDaily_WorkVigorousMins - Minutes of vigorous work activity (on a typical day) (phv00258807.v1.p1)
Walking_Cycling - Do you walk or cycle for more than 10 minutes? (phv00258792.v1.p1)
Walking_Cycling_Days - How many days per week do you walk or cycle? (days) (phv00258793.v1.p1)
Walking_Cycling_Hours - Time spent walking or cycling (hours) (phv00258794.v1.p1)
Walking_Cycling_Mins - Time spent walking or cycling (minutes) (phv00258795.v1.p1)
Work_Moderate - Does your work involve moderate activities? (phv00258787.v1.p1)
Work_Moderate_Days - How many days per week do you do moderate activity as part of your work? (days) (phv00258788.v1.p1)
Work_Moderate_Hours - Time spent doing work-related moderate activities (hours) (phv00258789.v1.p1)
Work_Moderate_Mins - Time spent doing work-related moderate activities (minutes) (phv00258790.v1.p1)
Work_Vigorous - Does your work involve vigorous activities? (phv00258783.v1.p1)
Work_Vigorous_Days - How many days per week do you do vigorous activity as part of your work? (days) (phv00258784.v1.p1)
Work_Vigorous_Hours - Time spent doing work-related vigorous activities (hours) (phv00258785.v1.p1)
Work_Vigorous_Mins - Time spent doing work-related vigorous activities (minutes) (phv00258786.v1.p1)
Workday_Length - Length of a typical work day (phv00258791.v1.p1)

General Health (23)

Daily_LeisureMVPA_Mins - Minutes of leisure time MVPA per day (phv00258828.v1.p1)
Daily_TotalMVPA_Mins - Total minutes of MVPA per day (phv00258825.v1.p1)
Daily_TransportMVPA_Mins - Minutes of transport-related (walking/cycling) MVPA per day (phv00258827.v1.p1)
Daily_WorkMVPA_Mins - Minutes of work-related MVPA per day (phv00258826.v1.p1)
Leisure_Moderate - Do you do moderate activities during your leisure time? (phv00258801.v1.p1)
Leisure_Moderate_Days - How many days per week do you do moderate activity in your leisure time? (days) (phv00258802.v1.p1)
Leisure_Moderate_Hours - Time spent doing moderate leisure time activities (hours) (phv00258803.v1.p1)
Leisure_Moderate_Mins - Time spent doing moderate leisure time activities (minutes) (phv00258804.v1.p1)
Leisure_Sitting - Do you spend most of your leisure time sitting? (phv00258796.v1.p1)
Leisure_Vigorous - Do you do vigorous activities during your leisure time? (phv00258797.v1.p1)
Leisure_Vigorous_Days - How many days per week do you do vigorous activity in your leisure time? (days) (phv00258798.v1.p1)
Leisure_Vigorous_Hours - Time spent doing vigorous leisure time activities (hours) (phv00258799.v1.p1)
Leisure_Vigorous_Mins - Time spent doing vigorous leisure time activities (minutes) (phv00258800.v1.p1)
MeetsWHO_Rec - Meets WHO Recommendations of >= 600 MET-minutes activity per week (phv00258819.v1.p1)
Mins_ModLeisure_Week - Moderate leisure activity (minutes per week) (phv00258824.v1.p1)
Mins_ModWork_Week - Moderate work activity (minutes per week) (phv00258821.v1.p1)
Mins_Transport_Week - Transport-related (walking/cycling) activity (minutes per week) (phv00258822.v1.p1)
Mins_VigLeisure_Week - Vigorous leisure activity (minutes per week) (phv00258823.v1.p1)
Mins_VigWork_Week - Vigorous work activity (minutes per week) (phv00258820.v1.p1)
No_LeisureMVPA - Reported no leisure time physical activity (phv00258831.v1.p1)
No_TransportMVPA - Reported no transport-related physical activity (phv00258830.v1.p1)
No_Vigorous - Repored no vigorous activity (across any category) (phv00258832.v1.p1)
No_WorkMVPA - Reported NO work related physical activity (phv00258829.v1.p1)

Geography (1)

Census_Region - Census Region of Samoa (phv00258677.v1.p1)

Medications (5)

Hd_meds - Are you taking medication for heart disease? (phv00258771.v1.p1)
Hyp_meds - Are you taking medication for hypertension? (phv00258749.v1.p1)
Past_hd_meds_years - How many years did you take meds for? (phv00258775.v1.p1)
Past_hyp_meds - Have you taken hypertension meds in the past? (phv00258751.v1.p1)
Past_hyp_meds_years - How many years did you take meds for? (phv00258752.v1.p1)

Reproductive Health (1)

Pregnant - Pregnancy status at enrollment (phv00258681.v1.p1)

Study Administration (3)

CONSENT - Consent group as determined by DAC (phv00258664.v1.p1)
Dec_Age - Age at enrollment (phv00258680.v1.p1)
Fasting - Fasting Status (phv00258726.v1.p1)

Substance Use (11)

Betel_quid - How many times per day do you use Betel / Quid? (phv00258721.v1.p1)
Cigars - Number of cigars per day (phv00258712.v1.p1)
Current_smoke - Current Smoker (phv00258705.v1.p1)
Hand_cigarettes - Number of hand-rolled cigarettes per day (phv00258710.v1.p1)
Man_cigarettes - Number of manufactured cigarettes per day (phv00258709.v1.p1)
Other_smokeless - How many times per day do you use other types of smokeless tobacco? (phv00258722.v1.p1)
Past_smoker - Past Smoker (phv00258713.v1.p1)
Pipes - Number of pipes per day (phv00258711.v1.p1)
Smokeless_tobacco_use - Do you use smokeless tobacco? (phv00258718.v1.p1)
Snuff_mouth - How many times per day do you use snuff by mouth? (phv00258719.v1.p1)
Snuff_nose - How many times per day do you use snuff by nose? (phv00258720.v1.p1)

Other (56)

Abd_Circ - Abdominal Circumference Average (phv00258690.v1.p1)
Abd_Skf - Abdominal Skinfold (Average) (phv00258696.v1.p1)
ANALYTE_TYPE - Analyte Type (phv00258841.v1.p1)
Arm_Circ - Arm Circumference Average (phv00258689.v1.p1)
Biochemistry_Complete - Participants biochemistry completed (phv00258728.v1.p1)
BODY_SITE - Body site where sample was collected (phv00258840.v1.p1)
Calf_Circ - Calf Circumference Average (phv00258692.v1.p1)
CUFFSIZE - Blood Pressure Cuff Size (phv00258700.v1.p1)
Db_traditional_healer - Have you seen a traditional healer for your diabetes? (phv00258763.v1.p1)
Db_traditional_meds - Are you taking traditional remedies for diabetes? (phv00258764.v1.p1)
Diabetes_treatment - Type of diabetes treatment (phv00258762.v1.p1)
Farming - Participants primary occupation is farming/plantation work (phv00258682.v1.p1)
For_Skf - Forearm Skinfold (Average) (phv00258694.v1.p1)
GWAS_BMI - Eligible participants genotyped and examined in GWAS of BMI (phv00258838.v1.p1)
GWAS_Eligible - Eligible for inclusion in the GWAS (phv00258678.v1.p1)
GWAS_Genotyped - Participants genotyped (phv00258836.v1.p1)
GWAS_Genotyped_Eligible - Eligible participants genotyped (phv00258837.v1.p1)
Hd_meds_name - Name of heart disease meds (phv00258772.v1.p1)
Hd_meds_years - How many years have you been taking heart disease meds? (phv00258773.v1.p1)
Hd_traditional_healer - Have you seen a traditional healer for your heart disease? (phv00258776.v1.p1)
Hd_traditional_meds - Are you taking traditional remedies for heart disease? (phv00258777.v1.p1)
Hip_Circ - Hip Circumference Average (phv00258691.v1.p1)
HRSSINCEATE - Hours since last ate (phv00258725.v1.p1)
Hyp_meds_years - How many years have you been taking these meds? (phv00258750.v1.p1)
Hyp_traditional_healer - Have you seen a traditional healer for your hypertension? (phv00258753.v1.p1)
Hyp_traditional_meds - Are you taking traditional remedies for hypertension? (phv00258754.v1.p1)
IS_TUMOR - Tumor status (phv00258842.v1.p1)
MET_ModLeisure_Week - MET value of moderate leisure activities per week (phv00258817.v1.p1)
MET_ModWork_Week - MET value of moderate work activity per week (phv00258814.v1.p1)
MET_Transport_Week - MET value of transport (walking/cycling) activity per week (phv00258815.v1.p1)
MET_VigLeisure_Week - MET value of vigorous leisure activities per week (phv00258816.v1.p1)
MET_VigWork_Week - MET value of vigorous work activity per week (phv00258813.v1.p1)
Past_hd_meds - Have you taken heart diseasemeds in the past? (phv00258774.v1.p1)
PLATE - Plate identifier (phv00258672.v1.p1)
PLATE - Plate (phv00258843.v1.p1)
REACT - Reactance (bioelectrical impedance analysis) (phv00258699.v1.p1)
RESIST - Resistance (bioelectrical impedance analysis) (phv00258698.v1.p1)
SAMPLE_ID - Sample ID (phv00258668.v1.p1)
SAMPLE_ID - De-identified Sample ID (phv00258839.v1.p1)
SAMPLE_SOURCE - Source repository where samples originate (phv00258669.v1.p1)
SAMPLE_USE - Sample Use (phv00258671.v1.p1)
SOURCE_SAMPLE_ID - Sample ID used in the Source Repository (phv00258670.v1.p1)
SOURCE_SUBJECT_ID - Subject ID used in the Source Repository (phv00258666.v1.p1)
SUBJECT_ID - De-identified Subject ID (phv00258674.v1.p1)
SUBJECT_ID - Subject ID (phv00258667.v1.p1)
SUBJECT_ID - Subject ID (phv00258663.v1.p1)
SUBJECT_SOURCE - Source repository where subjects originate (phv00258665.v1.p1)
Traditional_remedy_name_db - Name of traditional diabetes remedy (phv00258765.v1.p1)
Traditional_remedy_name_hd - Name of traditional heart disease remedy (phv00258778.v1.p1)
Traditional_remedy_name_hyp - Name of traditional hypertension remedy (phv00258755.v1.p1)
Twin - Which of a pair of twins used in genetic analyses (phv00258676.v1.p1)
Type_other_smokeless - What type of other smokeless tobacco do you use? (phv00258723.v1.p1)
Unrelated - Member of set of unrelated individuals as determined for BMI GWAS (phv00258675.v1.p1)
WELL - Well identifier (phv00258673.v1.p1)
WELL - Well (phv00258844.v1.p1)
Work_Sedentary - Does your work involve mostly sedentary activity? (phv00258782.v1.p1)