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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

Ke Zhang, Christopher J. Donnelly, A. Haeusler, et al. (2015). Nature. Cited 938 times. https://doi.org/10.1038/nature14973

C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins

Yong-Jie Zhang, Tania F. Gendron, J. Grima, et al. (2016). Nature Neuroscience. Cited 283 times. https://doi.org/10.1038/nn.4272

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease

A. Haeusler, Christopher J. Donnelly, J. Rothstein. (2016). Nature Reviews Neuroscience. Cited 194 times. https://doi.org/10.1038/nrn.2016.38

Revealing disease-associated pathways by network integration of untargeted metabolomics

Leila Pirhaji, P. Milani, Mathias Leidl, et al. (2016). Nature Methods. Cited 157 times. https://doi.org/10.1038/nmeth.3940

ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks

Ritchie Ho, S. Sances, G. Gowing, et al. (2016). Nature neuroscience. Cited 99 times. https://doi.org/10.1038/nn.4345

Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells

P. Milani, Renan Escalante-Chong, B. Shelley, et al. (2016). Scientific Reports. Cited 53 times. https://doi.org/10.1038/srep25474

Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD

Ke Zhang, J. Grima, J. Rothstein, et al. (2016). Nucleus. Cited 32 times. https://doi.org/10.1080/19491034.2016.1172152