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TOPDECC-Trans-omics for Precision Dentistry and Early Childhood Caries: Genome-Wide Genotyping (CIDR) and Microbiome in the ZOE 2.0 Study

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Anthropometry (3)

Demographics (4)

General Health (1)

  • FLTPASTE - Use of fluoride tooth paste every times child's teeth are brushed: yes, no, I don't know (phv00495442.v1.p1)

Race and Ethnicity (7)

Substance Use (1)

Other (57)

  • ANALYTE_TYPE - Analyte Type (phv00495484.v1.p1)
  • BEDWITHBOTTLE - Child has ever been put to bed with bottle with something other than water, yes/no (phv00495440.v1.p1)
  • CLUSTER_ID - Numeric ID defining the 34 study design clusters; i.e., public preschool programs attended by participants (phv00495425.v1.p1)
  • COHS - Guardian-reported child oral health status: excellent/very good/good/fair/poor (phv00495445.v1.p1)
  • CONSENT - Provided written informed consent (phv00495424.v1.p1)
  • CONSENT - Consent group (phv00495413.v1.p1)
  • DENTALPAIN - Child ever had a toothache or dental pain not due to teething, yes/no/I don't know (phv00495446.v1.p1)
  • DENTIST - Child has ever been to do the dentist, yes/no (phv00495443.v1.p1)
  • EDUC - Responding guardian's education level: some elementary/some high school/high school or GED/some technical or community college/college or more (phv00495444.v1.p1)
  • FAMILY_ID - Family ID (phv00495415.v1.p1)
  • FATHER - Father's Subject ID (phv00495417.v1.p1)
  • meta_t3_a - Case status of ECC defined at the ICDAS>=1 threshold, only considering teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495470.v1.p1)
  • meta_t3_b - Case status of ECC defined at the ICDAS>=1 threshold, only considering the 5 buccal/facial surfaces of teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495476.v1.p1)
  • meta_t3c_a - Continuous measure of caries (ECC) experience, defined at the ICDAS>=1 threshold, only considering teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495471.v1.p1)
  • meta_t3c_b - Continuous measure of caries (ECC) experience, defined at the ICDAS>=1 threshold, only considering the 5 buccal/facial surfaces of teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495477.v1.p1)
  • meta_t6_a - Case status of ECC defined at the ICDAS>=1 threshold, only considering teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495472.v1.p1)
  • meta_t6_b - Case status of ECC defined at the ICDAS>=3 threshold, only considering the 5 buccal/facial surfaces of teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495478.v1.p1)
  • meta_t6c_a - Continuous measure of caries (ECC) experience, defined at the ICDAS>=3 threshold, only considering teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495473.v1.p1)
  • meta_t6c_b - Continuous measure of caries (ECC) experience, defined at the ICDAS>=3 threshold, only considering the 5 buccal/facial surfaces of teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495479.v1.p1)
  • meta_t8_a - Case status of untreated ECC defined at the ICDAS>=3 threshold, only considering teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495474.v1.p1)
  • meta_t8_b - Case status of untreated ECC defined at the ICDAS>=3 threshold, only considering the 5 buccal/facial surfaces of teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495480.v1.p1)
  • meta_t8c_a - Continuous measure of untreated ECC experience, number of non-restored surfaces, only considering teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495475.v1.p1)
  • meta_t8c_b - Continuous measure of untreated ECC experience, number of non-restored surfaces, only considering the 5 buccal/facial surfaces of teeth #F, #G, #H, #I and #J (where plaque for metabolomics was collected from) (phv00495481.v1.p1)
  • micro_t3_a - Case status of ECC defined at the ICDAS>=1 threshold, only considering teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495458.v1.p1)
  • micro_t3_b - Case status of ECC defined at the ICDAS>=1 threshold, only considering the 5 buccal/facial surfaces of teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495464.v1.p1)
  • micro_t3c_a - Continuous measure of caries (ECC) experience, defined at the ICDAS>=1 threshold, only considering teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495459.v1.p1)
  • micro_t3c_b - Continuous measure of caries (ECC) experience, defined at the ICDAS>=1 threshold, only considering the 5 buccal/facial surfaces of teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495465.v1.p1)
  • micro_t6_a - Case status of ECC defined at the ICDAS>=3 threshold;, only considering teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495460.v1.p1)
  • micro_t6_b - Case status of ECC defined at the ICDAS>=3 threshold, only considering the 5 buccal/facial surfaces of teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495466.v1.p1)
  • micro_t6c_a - Continuous measure of caries (ECC) experience, defined at the ICDAS>=1 threshold, only considering teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495461.v1.p1)
  • micro_t6c_b - Continuous measure of caries (ECC) experience, defined at the ICDAS>=3 threshold, only considering the 5 buccal/facial surfaces of teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495467.v1.p1)
  • micro_t8_a - Case status of untreated ECC defined at the ICDAS>=3 threshold, only considering teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495462.v1.p1)
  • micro_t8_b - Case status of untreated ECC defined at the ICDAS>=3 threshold, only considering the 5 buccal/facial surfaces of teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495468.v1.p1)
  • micro_t8c_a - Continuous measure of untreated ECC experience, number of non-restored surfaces, only considering teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495463.v1.p1)
  • micro_t8c_b - Continuous measure of untreated ECC experience, number of non-restored surfaces, only considering the 5 buccal/facial surfaces of teeth #A, #B, #C, #D and #E (where plaque for DNA/RNA was collected from) (phv00495469.v1.p1)
  • MOTHER - Mother's Subject ID (phv00495418.v1.p1)
  • MZ_TWIN_ID - Twin pair ID (phv00495420.v1.p1)
  • OPTIMALWATERFLUORIDEIMPUTED - Binary indicator denoting directly measured domestic water source fluoride concentration >=0.60ppm F; directly measured for 25% of examined participants (phv00495455.v1.p1)
  • SAMPLE_ID - Sample ID (phv00495482.v1.p1)
  • SAMPLE_ID - Sample ID (phv00495422.v1.p1)
  • SOURCE - Biospecimen source of nucleic acids (phv00495483.v1.p1)
  • SSBS - Daily between-meal sugar containing snacks and beverages: 0-1, 2-3, 4+ (phv00495439.v1.p1)
  • SUBJECT_ID - Twice-removed ID from the original data collection identifier (phv00495423.v1.p1)
  • SUBJECT_ID - Subject ID (phv00495416.v1.p1)
  • SUBJECT_ID - Subject ID (phv00495412.v1.p1)
  • SUBJECT_ID - Subject ID (phv00495421.v1.p1)
  • t3 - Case status of ECC defined at the ICDAS>=1 threshold; i.e., presence of one or more tooth surfaces with caries experience defined at the early-stage caries lesion threshold (phv00495429.v1.p1)
  • t3c - Continuous measure of caries (ECC) experience, defined at the ICDAS>=1 threshold; i.e., the number of decayed, missing, or filled tooth surfaces (phv00495430.v1.p1)
  • t6 - Case status of ECC defined at the ICDAS>=3 threshold; i.e., presence of one or more tooth surfaces with caries experience defined at the moderate or advanced stage caries lesion threshold (phv00495427.v1.p1)
  • t6c - Continuous measure of caries (ECC) experience, defined at the ICDAS>=3 threshold; i.e., the number of decayed, missing, or filled tooth surfaces (phv00495428.v1.p1)
  • t8 - Case status of untreated ECC defined at the ICDAS>=3 threshold; i.e., presence of one or more tooth surfaces with untreated caries lesions defined at the moderate or advanced stage caries lesion threshold (phv00495456.v1.p1)
  • t8c - Continuous measure of untreated ECC experience, defined at the ICDAS>=3 threshold; i.e., number of untreated moderate-advanced caries lesions (phv00495457.v1.p1)
  • WSOURCE_BOTTLE - Primary source of home drinking water for child is bottled water, yes/no (phv00495451.v1.p1)
  • WSOURCE_COMM - Primary source of home drinking water for child is city or community water, yes/no (phv00495452.v1.p1)
  • WSOURCE_FILTER - Primary source of home drinking water for child is filtered water, yes/no (phv00495453.v1.p1)
  • WSOURCE_NOWATER - Primary source of home drinking water for child is not applicable because child does not drink water, yes/no (phv00495454.v1.p1)
  • WSOURCE_WELL - Primary source of home drinking water for child is well water, yes/no (phv00495450.v1.p1)