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Multicenter Study of Hydroxyurea (MSH)

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.

S. Charache, M. Terrin, R. Moore, et al. (1995). The New England journal of medicine. Cited 2,244 times. https://doi.org/10.1056/NEJM199505183322001

Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.

M. Steinberg, F. Barton, O. Castro, et al. (2003). JAMA. Cited 972 times. https://doi.org/10.1001/JAMA.289.13.1645

Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea.

M. Steinberg, Z. Lu, F. Barton, et al. (1997). Blood. Cited 411 times. https://doi.org/10.1182/BLOOD.V89.3.1078

Hydroxyurea and Sickle Cell Anemia Clinical Utility of a Myelosuppressive “Switching” Agent

S. Charache, F. Barton, R. Moore, et al. (1996). Medicine. Cited 353 times. https://doi.org/10.1097/00005792-199611000-00002

Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia.

S. Charache, G. Dover, Richard D. Moore, et al. (1992). Blood. Cited 298 times. https://doi.org/10.1182/BLOOD.V79.10.2555.BLOODJOURNAL79102555

Design of the multicenter study of hydroxyurea in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea.

S. Charache, M. Terrin, R. Moore, et al. (1995). Controlled clinical trials. Cited 269 times. https://doi.org/10.1016/S0197-2456(95)00098-4

Mechanism of action of hydroxyurea in the management of sickle cell anemia in adults.

S. Charache. (1997). Seminars in hematology. Cited 176 times.

Cost‐effectiveness of hydroxyurea in sickle cell anemia

Richard D. Moore, S. Charache, M. Terrin, et al. (2000). American Journal of Hematology. Cited 118 times. https://doi.org/10.1002/(SICI)1096-8652(200005)64:1<26::AID-AJH5>3.0.CO;2-F

Effects of hydroxyurea administration on the body weight, body composition and exercise performance of patients with sickle-cell anaemia.

A. Hackney, W. Hezier, T. Gulledge, et al. (1997). Clinical science. Cited 43 times. https://doi.org/10.1042/CS0920481

Fetal hemoglobin in sickle cell anemia: relation to regulatory sequences cis to the beta-globin gene. Multicenter Study of Hydroxyurea.

Zhou Lu, M. Steinberg. (1996). Blood. Cited 16 times. https://doi.org/10.1182/BLOOD.V87.4.1604.BLOODJOURNAL8741604

An extension of stochastic curtailment for incompletely reported and classified recurrent events: the Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH).

R. Mcmahon, M. Waclawiw, N. Geller, et al. (1997). Controlled clinical trials. Cited 10 times. https://doi.org/10.1016/S0197-2456(97)00014-7