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The Human Pancreas Analysis Program (HPAP)

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Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.

Y. Wang, D. Traum, J. Schug, et al. (2019). Cell metabolism. Cited 178 times. https://doi.org/10.1016/j.cmet.2019.01.003

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells

K. Coate, J. Cha, Shristi Shrestha, et al. (2020). Cell Metabolism. Cited 140 times. https://doi.org/10.1016/j.cmet.2020.11.006

NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)

K. Kaestner, A. Powers, A. Naji, et al. (2019). Diabetes. Cited 133 times. https://doi.org/10.2337/db19-0058

Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in Type 1 Diabetes

Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, et al. (2022). Nature metabolism. Cited 126 times. https://doi.org/10.1038/s42255-022-00531-x

Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D

D. Avrahami, Y. Wang, J. Schug, et al. (2020). Molecular Metabolism. Cited 76 times. https://doi.org/10.1016/j.molmet.2020.101057

Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression.

Maria Fasolino, N. Goldman, Wenlian Wang, et al. (2020). Immunity. Cited 47 times. https://doi.org/10.1016/j.immuni.2020.01.003

Understanding islet dysfunction in type 2 diabetes through multidimensional pancreatic phenotyping: The Human Pancreas Analysis Program.

Suzanne N. Shapira, Ali Naji, Mark A. Atkinson, et al. (2022). Cell metabolism. Cited 39 times. https://doi.org/10.1016/j.cmet.2022.09.013

TCR+/BCR+ dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes

A. S. Japp, Wenzhao Meng, Aaron M. Rosenfeld, et al. (2021). Cell. Cited 19 times. https://doi.org/10.1016/j.cell.2020.11.035

Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program

Abhijeet R. Patil, J. Schug, Ali Naji, et al. (2023). Nature Metabolism. Cited 18 times. https://doi.org/10.1038/s42255-023-00806-x