Glioma study with SNP Genotypes (Array) data on dbGaP (794 participants)

phs003041 — Mayo Clinic Adult Diffuse Glioma Illumina OncoArray SNP Data

<p>These data are from adult diffuse glioma subjects genotyped on the Illumina OncoArray. Data from this study were used for case control association studies and developing polygenic risk scores. Variants in <a href="https://www.ncbi.nlm.nih.gov/gene/728294">D2HGDH</a> and near <a href="https://www.ncbi.nlm.nih.gov/gene/56975">FAM20C</a> were identified that were associated with glioma subtypes (<a href="https://pubmed.ncbi.nlm.nih.gov/32386320/">PMID: 32386320</a>). Mutation and copy number data are included for select genes and chromosomes. IDH mutation and 1p/19q co-deletion are used in glioma diagnosis and are also prognostic markers. Data for additional prognostic genes and chromosomes are also included. RNA-seq and CHIP-seq data are available for select subjects from this cohort in GEO (<a href="https://www.ncbi.nlm.nih.gov/gds/?term=GSE167806">GSE167806</a>).</p>