Liquid Biopsy study with WGS data on dbGaP (213 participants)

phs003170 — Genome-Wide Analysis of Aberrant Position and Sequence of Plasma DNA    Fragment Ends in Patients With Cancer

<p>This study investigated fragmentation characteristics in plasma cell-free DNA and evaluated the relevance of such analysis for cancer diagnostics. Specifically, we performed whole genome sequencing (WGS) of healthy individuals and cancer patients, and evaluated genome-wide coverage and sequences surrounding fragment ends. This was a retrospective study of archived plasma samples. The WGS data are available through this submission. Detailed study design and findings were published in <a href="https://pubmed.ncbi.nlm.nih.gov/36630480/">Budhraja <i>et al</i>. Science Translational Medicine 2023</a>. </p>