Dental Caries: Whole Genome Association and Gene x Environment Studies

Genome-wide Association Studies

J. R. Shaffer, E. Feingold, M. Marazita. (2012). Journal of Dental Research. Cited 980 times. https://doi.org/10.1177/0022034512446968

Dental caries and childhood obesity: roles of diet and socioeconomic status.

T. Marshall, Julie M. Eichenberger-Gilmore, B. Broffitt, et al.. (2007). Community dentistry and oral epidemiology. Cited 261 times. https://doi.org/10.1111/J.1600-0528.2006.00353.X

Taste Genes Associated with Dental Caries

S. Wendell, Xiaojing Wang, M. Brown, et al.. (2010). Journal of Dental Research. Cited 153 times. https://doi.org/10.1177/0022034510381502

Caries: Review of Human Genetics Research

A. R. Vieira, A. Modesto, M. Marazita. (2014). Caries Research. Cited 148 times. https://doi.org/10.1159/000358333

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

M. Graff, J. Ngwa, J. Ngwa, et al.. (2013). Human molecular genetics. Cited 121 times. https://doi.org/10.1093/hmg/ddt205

Genome-wide Association Scan for Childhood Caries Implicates Novel Genes

J. Shaffer, X. Wang, E. Feingold, et al.. (2011). Journal of Dental Research. Cited 120 times. https://doi.org/10.1177/0022034511422910

Study protocol of the Center for Oral Health Research in Appalachia (COHRA) etiology study

D. Polk, R. Weyant, R. Crout, et al.. (2008). BMC Oral Health. Cited 90 times. https://doi.org/10.1186/1472-6831-8-18

GWAS of Dental Caries Patterns in the Permanent Dentition

J. Shaffer, Eleanor Feingold, Xiaojing Wang, et al.. (2013). Journal of Dental Research. Cited 87 times. https://doi.org/10.1177/0022034512463579

Genome-wide association Scan of dental caries in the permanent dentition

Xiaojing Wang, J. Shaffer, Z. Zeng, et al.. (2012). BMC Oral Health. Cited 86 times. https://doi.org/10.1186/1472-6831-12-57

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Sarah M. Hartz, S. Short, N. Saccone, et al.. (2012). Archives of general psychiatry. Cited 80 times. https://doi.org/10.1001/archgenpsychiatry.2012.124

Relative validity of the Iowa Fluoride Study targeted nutrient semi-quantitative questionnaire and the block kids' food questionnaire for estimating beverage, calcium, and vitamin D intakes by children.

T. Marshall, Julie M. Eichenberger Gilmore, B. Broffitt, et al.. (2008). Journal of the American Dietetic Association. Cited 73 times. https://doi.org/10.1016/j.jada.2007.12.002

Genome-wide Association Studies of Pit-and-Fissure- and Smooth-surface Caries in Permanent Dentition

Zhen Zeng, J. Shaffer, Xiaojing Wang, et al.. (2013). Journal of Dental Research. Cited 64 times. https://doi.org/10.1177/0022034513481976

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Cathy C. Laurie, C. Laurie, Kenneth M. Rice, et al.. (2012). Nature genetics. Cited 62 times. https://doi.org/10.1038/ng.2271

Genome-Wide Association Study of Periodontal Health Measured by Probing Depth in Adults Ages 18−49 years

J. Shaffer, D. Polk, Xiaojing Wang, et al.. (2013). G3: Genes|Genomes|Genetics. Cited 62 times. https://doi.org/10.1534/g3.113.008755

Genetic Susceptibility to Dental Caries on Pit and Fissure and Smooth Surfaces

J. Shaffer, Xuexia Wang, R. DeSensi, et al.. (2012). Caries Research. Cited 60 times. https://doi.org/10.1159/000335099

Phenotype harmonization and cross‐study collaboration in GWAS consortia: the GENEVA experience

Siiri N. Bennett, N. Caporaso, A. Fitzpatrick, et al.. (2011). Genetic Epidemiology. Cited 57 times. https://doi.org/10.1002/gepi.20564

Genome-Wide Association Study Identifies Four Loci Associated with Eruption of Permanent Teeth

F. Geller, B. Feenstra, Hao Zhang, et al.. (2011). PLoS Genetics. Cited 48 times. https://doi.org/10.1371/journal.pgen.1002275

Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges.

A. Agrawal, N. Freedman, Yuching Cheng, et al.. (2012). The American journal of clinical nutrition. Cited 39 times. https://doi.org/10.3945/ajcn.111.015545

Heritable patterns of tooth decay in the permanent dentition: principal components and factor analyses

J. Shaffer, E. Feingold, Xiaojing Wang, et al.. (2012). BMC Oral Health. Cited 39 times. https://doi.org/10.1186/1472-6831-12-7

Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries

Zhen Zeng, E. Feingold, Xiao-Jing Wang, et al.. (2014). Caries Research. Cited 39 times. https://doi.org/10.1159/000356299

Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking

Sarah H. Stephens, Sarah M. Hartz, Nicole R. Hoft, et al.. (2013). Genetic Epidemiology. Cited 35 times. https://doi.org/10.1002/gepi.21760

Demographic, socioeconomic, and behavioral factors affecting patterns of tooth decay in the permanent dentition: principal components and factor analyses.

J. Shaffer, D. Polk, E. Feingold, et al.. (2013). Community dentistry and oral epidemiology. Cited 33 times. https://doi.org/10.1111/cdoe.12016

Clustering Tooth Surfaces into Biologically Informative Caries Outcomes

J. Shaffer, Eleanor Feingold, Xiaojing Wang, et al.. (2013). Journal of Dental Research. Cited 31 times. https://doi.org/10.1177/0022034512463241

Genetic Association of MPPED2 and ACTN2 with Dental Caries

Brooklyn Stanley, E. Feingold, M. Cooper, et al.. (2014). Journal of Dental Research. Cited 29 times. https://doi.org/10.1177/0022034514534688

Multi-Dimensional Prioritization of Dental Caries Candidate Genes and Its Enriched Dense Network Modules

Quan Wang, P. Jia, K. Cuenco, et al.. (2013). PLoS ONE. Cited 27 times. https://doi.org/10.1371/journal.pone.0076666

Exploring the effect of dentition, dental decay and familiality on oral health using metabolomics.

B. Foxman, U. Srinivasan, Ai Wen, et al.. (2014). Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. Cited 25 times. https://doi.org/10.1016/j.meegid.2013.09.020

Association Signals Unveiled by a Comprehensive Gene Set Enrichment Analysis of Dental Caries Genome-Wide Association Studies

Quan Wang, P. Jia, K. Cuenco, et al.. (2013). PLoS ONE. Cited 16 times. https://doi.org/10.1371/journal.pone.0072653

Effects of Smoking and Genotype on the PSR Index of Periodontal Disease in Adults Aged 18–49

D. Polk, Xiaojing Wang, E. Feingold, et al.. (2012). International Journal of Environmental Research and Public Health. Cited 15 times. https://doi.org/10.3390/ijerph9082839

Detection of Streptococcus mutans Genomic DNA in Human DNA Samples Extracted from Saliva and Blood

A. R. Vieira, K. Deeley, N. Callahan, et al.. (2011). ISRN Dentistry. Cited 13 times. https://doi.org/10.5402/2011/543561

Using Family Data as a Verification Standard to Evaluate Copy Number Variation Calling Strategies for Genetic Association Studies

Xiaojing Zheng, J. Shaffer, Caitlin P. McHugh, et al.. (2012). Genetic Epidemiology. Cited 11 times. https://doi.org/10.1002/gepi.21618

Caries Resistance as a Function of Age in an Initially Caries-free Population

Ai Wen, Deborah E. Goldberg, C. Marrs, et al.. (2012). Journal of Dental Research. Cited 10 times. https://doi.org/10.1177/0022034512450174

Genome-wide Two-marker linkage disequilibrium mapping of quantitative trait loci

Jie Yang, Wei Zhu, Jiansong Chen, et al.. (2014). BMC Genetics. Cited 6 times. https://doi.org/10.1186/1471-2156-15-20

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants.

C. Laurie, C. Laurie, S. Smoley, et al.. (2014). Cancer genetics. Cited 6 times. https://doi.org/10.1016/j.cancergen.2014.01.004