<p>The goal of this collaborative study was to identify new genetic risk factors for Systemic Lupus Erythematosus (SLE).  To do this
</p><pre><code>  we conducted a genome-wide scan by combining the resources and expertise from a number of SLE researchers to establish a large

  sample set comprising 1311 SLE cases and 3340 controls.  The SLE case samples were genotyped from the following collections:  338

  subjects from the Autoimmune Biomarkers Collaborative Network (ABCoN), an NIH/NIAMS funded repository, 141 subjects from the

  Multiple Autoimmune Disease Genetics Consortium (MADGC), 613 subjects from the University of California San Francisco (UCSF) Lupus

  Genetics, and 335 subjects from the University of Pittsburgh Medical Center (UPMC), plus 8 samples collected at The Feinstein

  Institute for Medical Research.&#x3C;/p>

  &#x3C;p>A total of 3583 control samples were examined in the association analyses.  As part of this project, 1861 control samples were

  selected and then genotyped from the New York Cancer Project (NYCP), based on self-described ethnicity, gender and age.

  In addition, genotype data from 1722 control samples (all self-described North Americans of European descent) were obtained from

  the publicly available iControlDB database (&#x3C;a href="http://www.illumina.com/pages.ilmn?ID=231" target="_blank">http://www.illumina.com/pages.ilmn?ID=231&#x3C;/a>).
</code></pre>
<p></p>

Whole Genome Association Study of Systemic Lupus Erythematosus

Description

Applying For Access

Summary