A Whole Genome Association Search for Type 2 Diabetes Genes in African Americans

Genetic factors in diabetic nephropathy.

B. Freedman, Meredith A. Bostrom, Pirouz Daeihagh, et al.. (2007). Clinical journal of the American Society of Nephrology : CJASN. Cited 197 times. https://doi.org/10.2215/CJN.02560607

A genome scan for diabetic nephropathy in African Americans.

D. Bowden, Carla J Colicigno, C. Langefeld, et al.. (2004). Kidney international. Cited 187 times. https://doi.org/10.1111/J.1523-1755.2004.00915.X

Association Analysis in African Americans of European-Derived Type 2 Diabetes Single Nucleotide Polymorphisms From Whole-Genome Association Studies

J. Lewis, Nicholette D. Palmer, P. Hicks, et al.. (2008). Diabetes. Cited 149 times. https://doi.org/10.2337/db07-1319

A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.

B. Freedman, P. Hicks, M. Sale, et al.. (2007). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Cited 130 times. https://doi.org/10.1093/NDT/GFL717

Variants of the Transcription Factor 7-Like 2 (TCF7L2) Gene Are Associated With Type 2 Diabetes in an African-American Population Enriched for Nephropathy

M. Sale, Shelly G. Smith, J. Mychaleckyj, et al.. (2007). Diabetes. Cited 125 times. https://doi.org/10.2337/db07-0012

Relationship between albuminuria and cardiovascular disease in Type 2 diabetes.

B. Freedman, C. Langefeld, K. Lohman, et al.. (2005). Journal of the American Society of Nephrology : JASN. Cited 78 times. https://doi.org/10.1681/ASN.2004100884

Genetic linkage analysis of growth factor loci and end-stage renal disease in African Americans.

B. Freedman, Hongrun Yu, B. J. Spray, et al.. (1997). Kidney international. Cited 76 times. https://doi.org/10.1038/KI.1997.115

A genome-wide scan for type 2 diabetes in African-American families reveals evidence for a locus on chromosome 6q.

M. Sale, B. Freedman, C. Langefeld, et al.. (2004). Diabetes. Cited 75 times. https://doi.org/10.2337/DIABETES.53.3.830

Genetic analysis of nitric oxide and endothelin in end-stage renal disease.

B. I. Freedman, Hongrun Yu, Pamela J. Anderson, et al.. (2000). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Cited 68 times. https://doi.org/10.1093/NDT/15.11.1794

Identification of human plasma kallikrein gene polymorphisms and evaluation of their role in end-stage renal disease.

Hongrun Yu, D. Bowden, B. J. Spray, et al.. (1998). Hypertension. Cited 61 times. https://doi.org/10.1161/01.HYP.31.4.906

Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.

Hongrun Yu, Pamela J. Anderson, B. I. Freedman, et al.. (2000). Genomics. Cited 61 times. https://doi.org/10.1006/GENO.2000.6330

Linkage analysis between loci in the renin-angiotensin axis and end-stage renal disease in African Americans.

H. Yu, D. Bowden, B. J. Spray, et al.. (1996). Journal of the American Society of Nephrology : JASN. Cited 57 times.

Association of the tissue kallikrein gene promoter with ESRD and hypertension.

Hongrun Yu, Q. Song, B. Freedman, et al.. (2002). Kidney international. Cited 50 times. https://doi.org/10.1046/J.1523-1755.2002.00198.X

Race-Specific Relationships Between Coronary and Carotid Artery Calcification and Carotid Intimal Medial Thickness

L. Wagenknecht, C. Langefeld, J. J. Carr, et al.. (2004). Stroke: Journal of the American Heart Association. Cited 50 times. https://doi.org/10.1161/01.STR.0000127081.99767.1d

A genome scan for all-cause end-stage renal disease in African Americans.

B. Freedman, D. Bowden, S. Rich, et al.. (2005). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Cited 45 times. https://doi.org/10.1093/NDT/GFH704

Nephropathy in siblings of African Americans with overt type 2 diabetic nephropathy.

S. Satko, C. Langefeld, Pirouz Daeihagh, et al.. (2002). American journal of kidney diseases : the official journal of the National Kidney Foundation. Cited 44 times. https://doi.org/10.1053/AJKD.2002.34888

Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster.

J. Bensen, C. Langefeld, G. Hawkins, et al.. (2003). Genomics. Cited 43 times. https://doi.org/10.1016/S0888-7543(03)00123-X

Evaluation of genetic variation and association in the matrix metalloproteinase 9 (MMP9) gene in ESRD patients.

S. Hirakawa, E. Lange, Carla J Colicigno, et al.. (2003). American journal of kidney diseases : the official journal of the National Kidney Foundation. Cited 40 times. https://doi.org/10.1016/S0272-6386(03)00416-5

Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population.

Tennille S. Leak, Keith L. Keene, C. Langefeld, et al.. (2007). Molecular genetics and metabolism. Cited 39 times. https://doi.org/10.1016/J.YMGME.2007.05.014

Association of the Distal Region of the Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Gene With Type 2 Diabetes in an African-American Population Enriched for Nephropathy

Keith L. Keene, J. Mychaleckyj, Shelly G. Smith, et al.. (2008). Diabetes. Cited 35 times. https://doi.org/10.2337/db07-0886

The role of genetic factors in the development of end-stage renal disease.

Barry I. Freedman, D. Bowden. (1995). Current opinion in nephrology and hypertension. Cited 34 times. https://doi.org/10.1097/00041552-199505000-00005

Investigation of the Estrogen Receptor-α Gene With Type 2 Diabetes and/or Nephropathy in African-American and European-American Populations

C. Gallagher, Keith L. Keene, J. Mychaleckyj, et al.. (2007). Diabetes. Cited 33 times. https://doi.org/10.2337/db06-0303

Genetic susceptibility contributes to renal and cardiovascular complications of type 2 diabetes mellitus.

B. Freedman, D. Bowden, M. Sale, et al.. (2006). Hypertension. Cited 32 times. https://doi.org/10.1161/01.HYP.0000227047.26988.3E

Evaluation of markers on human chromosome 10, including the homologue of the rodent Rf-1 gene, for linkage to ESRD in black patients.

H. Yu, M. Sale, S. Rich, et al.. (1999). American journal of kidney diseases : the official journal of the National Kidney Foundation. Cited 31 times. https://doi.org/10.1016/S0272-6386(99)70303-3

Comprehensive evaluation of the estrogen receptor α gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population

Keith L. Keene, J. Mychaleckyj, Shelly G. Smith, et al.. (2008). Human Genetics. Cited 28 times. https://doi.org/10.1007/s00439-008-0482-z

Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease

Keith L. Keene, J. Mychaleckyj, Tennille S. Leak, et al.. (2008). Human Genetics. Cited 28 times. https://doi.org/10.1007/s00439-008-0532-6

Genetic initiation of hypertensive and diabetic nephropathy.

B. Freedman, D. Bowden, S. Rich, et al.. (1998). American journal of hypertension. Cited 27 times. https://doi.org/10.1016/S0895-7061(97)00481-0

Loci Contributing to Adult Height and Body Mass Index in African American Families Ascertained for Type 2 Diabetes

M. Sale, B. Freedman, P. Hicks, et al.. (2005). Annals of Human Genetics. Cited 23 times. https://doi.org/10.1046/j.1529-8817.2005.00176.x

Evaluation of a SNP map of 6q24–27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population

Tennille S. Leak, J. Mychaleckyj, Shelly G. Smith, et al.. (2008). Human Genetics. Cited 15 times. https://doi.org/10.1007/s00439-008-0523-7

Human Na+/H+ exchanger genes : identification of polymorphisms by radiation hybrid mapping and analysis of linkage in end-stage renal disease.

H. Yu, B. Freedman, S. Rich, et al.. (2000). Hypertension. Cited 13 times. https://doi.org/10.1161/01.HYP.35.1.135

Prevalence of Nephropathy in Black Patients with Type 2 Diabetes mellitus

J. Gitter, C. Langefeld, S. Rich, et al.. (2002). American Journal of Nephrology. Cited 13 times. https://doi.org/10.1159/000046672

Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.

J. Bensen, C. Langefeld, Liwu Li, et al.. (2003). Kidney international. Cited 13 times.

Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population.

C. Gallagher, C. Gordon, C. Langefeld, et al.. (2006). Molecular genetics and metabolism. Cited 13 times.

Trends in racial disparities in care.

B. Freedman, L. Wagenknecht, D. Bowden. (2005). The New England journal of medicine.