A Whole Genome Association Search for Type 2 Diabetes Genes in African Americans
Ancestry (20)
- pc1 - Principal component 1: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076433.v1.p1)
- pc1 - Principal component 1: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076443.v1.p1)
- pc10 - Principal component 10: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076442.v1.p1)
- pc10 - Principal component 10: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076452.v1.p1)
- pc2 - Principal component 2: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076434.v1.p1)
- pc2 - Principal component 2: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076444.v1.p1)
- pc3 - Principal component 3: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076435.v1.p1)
- pc3 - Principal component 3: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076445.v1.p1)
- pc4 - Principal component 4: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076436.v1.p1)
- pc4 - Principal component 4: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076446.v1.p1)
- pc5 - Principal component 5: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076437.v1.p1)
- pc5 - Principal component 5: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076447.v1.p1)
- pc6 - Principal component 6: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076438.v1.p1)
- pc6 - Principal component 6: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076448.v1.p1)
- pc7 - Principal component 7: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076439.v1.p1)
- pc7 - Principal component 7: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076449.v1.p1)
- pc8 - Principal component 8: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076440.v1.p1)
- pc8 - Principal component 8: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076450.v1.p1)
- pc9 - Principal component 9: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076441.v1.p1)
- pc9 - Principal component 9: a mathematical tool commonly used in statistical analysis. It seeks to identify an orthogonal coordinate system that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components (PC). This method allows for the separation of individuals on the basis of differences in their properties and can also be used to evaluate the properties that contribute the most to these separations. The principal components are ordered in terms of the amount of variation in the dataset that they explain such that the first PC explains the largest fraction of the total variance, and so on. There exist a number of methods to determine the number of PC to be retained for a specific analysis. However, none of them uniformly dominates the others. Following a practice largely adopted in the field, we present the first 10 PC computed on this dataset. (phv00076451.v1.p1)
Anthropometry (2)
- BMI - Body Mass Index (phv00066341.v1.p1)
- BMI - Body Mass Index (phv00066355.v1.p1)
Demographics (4)
- Age - Age at recruitment (phv00066339.v1.p1)
- Age - Age at recruitment (phv00066353.v1.p1)
- Gender - Gender of participant has been confirmed with genotyping: 1 = Male, 2 = Female (phv00066340.v1.p1)
- Gender - Gender of participant has been confirmed with genotyping: 1 = Male, 2 = Female (phv00066354.v1.p1)
Disease Events (7)
- Duration T2DM - Duration of T2DM (Type 2 Diabetes Mellitus) since diagnosis (phv00066346.v1.p1)
- ESRD - Individual has reported that he/she is on dialysis (phv00066347.v1.p1)
- ESRD Age of Onset - Age of ESRD (End Stage Renal Disease) diagnosis, start of dialysis (phv00066344.v1.p1)
- FBS - Fasting Blood Sugar (phv00066356.v1.p1)
- HBA1C - Hemoglobin1AC, test (phv00066350.v1.p1)
- HTN Age of Onset - Age of hypertension diagnosis (phv00066345.v1.p1)
- T2DM Age of Onset - Age of T2DM (Type 2 Diabetes Mellitus) diagnosis (phv00066343.v1.p1)
General Health (1)
- Retinopathy - Individual has diabetic retinopathy reported by ophthalmologist or laser treatment with photocoagulation (phv00066349.v1.p1)
Medications (1)
- HTN - Individual has self reported hypertension (yes, no, unknown) (phv00066348.v1.p1)
Race and Ethnicity (2)
- Race - Race, ethnicity of participant (phv00066338.v1.p1)
- Race - Race, ethnicity of participant (phv00066352.v1.p1)
Study Administration (1)
- Fasting status - Participant is fasting when he has not had anything to eat or drink 12 hours prior to blood draw. (phv00066358.v1.p1)
Other (14)
- ANALYTE_TYPE - Analyte type (phv00265634.v1.p1)
- BODY_SITE - Body site where sample was collected (phv00265633.v1.p1)
- Consent - Consent form(s) signed by participant (phv00066342.v1.p1)
- Consent - Consent form(s) signed by participant (phv00066357.v1.p1)
- FAMID - Family ID (phv00076455.v1.p1)
- FATHER - Father's subject ID (phv00076458.v1.p1)
- IS_TUMOR - Tumor status (phv00265635.v1.p1)
- MOTHER - Mother's subject ID (phv00076457.v1.p1)
- MZ_TWIN_ID - Twin ID (phv00076460.v2.p1)
- SAMPID - De-identified sample ID (phv00265632.v1.p1)
- SEX - Sex (phv00076459.v1.p1)
- SUBJID - Subject ID (phv00066337.v1.p1)
- SUBJID - Subject ID (phv00066351.v1.p1)
- SUBJID - Unique subject ID (phv00076456.v1.p1)