<p>An important potential enabling resource for Personalized Medicine is the combination of a DNA repository with Electronic  Medical Record (EMR) systems sufficiently robust to provide excellence in clinical care and to serve as resources for  analysis of disease susceptibility and therapeutic outcomes across patient populations. The Vanderbilt EMR is a state of  the art clinical and research tool (that includes >1.7 million records), and is associated with a DNA repository which has  been in development for over 3 years; these are the key components of VGER, the Vanderbilt Genome-Electronic Records project,  a part of NHGRI's eMERGE network. The VGER model acquires DNA from discarded blood samples collected from routine patient care,  and can link these to de-identified data extracted and readily updated from the EMR. The phenotype we analyze here is the QRS  duration on the electrocardiogram, since slow conduction (indicated by longer QRS duration) is a marker of arrhythmia  susceptibility.</p>

Vanderbilt Genome-Electronic Records (VGER) Project: QRS Duration

Heart Conduction System study with SNP Genotypes (Array) data on dbGaP (3,021 participants)