National Cancer Institute (NCI) TARGET: Therapeutically Applicable Research to Generate Effective Treatments

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

C. Mullighan, X. Su, Jinghui Zhang, et al.. (2009). The New England journal of medicine. Cited 1,304 times. https://doi.org/10.1056/NEJMoa0808253

The genetic landscape of high-risk neuroblastoma

Trevor J Pugh, O. Morozova, E. Attiyeh, et al.. (2013). Nature genetics. Cited 1,090 times. https://doi.org/10.1038/ng.2529

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.

K. Roberts, Ryan D. Morin, Jinghui Zhang, et al.. (2012). Cancer cell. Cited 704 times. https://doi.org/10.1016/j.ccr.2012.06.005

JAK mutations in high-risk childhood acute lymphoblastic leukemia

C. Mullighan, Jinghui Zhang, R. Harvey, et al.. (2009). Proceedings of the National Academy of Sciences. Cited 593 times. https://doi.org/10.1073/pnas.0811761106

Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia.

R. Harvey, R. Harvey, C. Mullighan, et al.. (2010). Blood. Cited 561 times. https://doi.org/10.1182/blood-2009-09-245944

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.

R. Harvey, R. Harvey, C. Mullighan, et al.. (2010). Blood. Cited 409 times. https://doi.org/10.1182/blood-2009-08-239681

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Jinghui Zhang, C. Mullighan, R. Harvey, et al.. (2011). Blood. Cited 301 times. https://doi.org/10.1182/blood-2011-03-341412

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia.

Huining Kang, I. Chen, Carla S. Wilson, et al.. (2010). Blood. Cited 175 times. https://doi.org/10.1182/blood-2009-05-218560

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project.

(2013). Blood. Cited 141 times. https://doi.org/10.1182/blood-2012-04-422691