PREDICT-HD Huntington Disease Study

Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

N. Tzourio-Mazoyer, B. Landeau, D. Papathanassiou, et al.. (2002). NeuroImage. Cited 16,108 times. https://doi.org/10.1006/nimg.2001.0978

Detection of Huntington’s disease decades before diagnosis: the Predict-HD study

Jane S. Paulsen, D. Langbehn, J. Stout, et al.. (2007). Journal of Neurology, Neurosurgery, and Psychiatry. Cited 868 times. https://doi.org/10.1136/jnnp.2007.128728

A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length

D. Langbehn, R. Brinkman, D. Falush, et al.. (2004). Clinical Genetics. Cited 812 times. https://doi.org/10.1111/j.1399-0004.2004.00241.x

Onset and rate of striatal atrophy in preclinical Huntington disease

E. Aylward, B. Sparks, K. Field, et al.. (2004). Neurology. Cited 400 times. https://doi.org/10.1212/01.WNL.0000132965.14653.D1

Psychiatric Symptoms in Huntington’s Disease before Diagnosis: The Predict-HD Study

K. Duff, Jane S. Paulsen, L. Beglinger, et al.. (2007). Biological Psychiatry. Cited 395 times. https://doi.org/10.1016/j.biopsych.2006.11.034

CAG‐repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches

D. Langbehn, M. Hayden, Jane S. Paulsen. (2010). American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Cited 358 times. https://doi.org/10.1002/ajmg.b.30992

Brain Structure in Preclinical Huntington’s Disease

Jane S. Paulsen, V. Magnotta, A. Mikos, et al.. (2006). Biological Psychiatry. Cited 244 times. https://doi.org/10.1016/j.biopsych.2005.06.003

Preparing for preventive clinical trials: the Predict-HD study.

J. Paulsen, Michael R. Hayden, J. C. Stout, et al.. (2006). Archives of neurology. Cited 198 times.

"Frontal" behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness.

K. Duff, Jane S. Paulsen, L. Beglinger, et al.. (2010). The Journal of neuropsychiatry and clinical neurosciences. Cited 186 times. https://doi.org/10.1176/appi.neuropsych.22.2.196

Motor abnormalities in premanifest persons with Huntington's disease: The PREDICT‐HD study

K. Biglan, C. Ross, D. Langbehn, et al.. (2009). Movement Disorders. Cited 151 times. https://doi.org/10.1002/mds.22601

Regional white matter change in pre-symptomatic Huntington's disease: A diffusion tensor imaging study

Sarah A. J. Reading, M. Yassa, A. Bakker, et al.. (2005). Psychiatry Research: Neuroimaging. Cited 150 times. https://doi.org/10.1016/j.pscychresns.2005.05.011

Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease

E. Aylward. (2007). Brain Research Bulletin. Cited 140 times. https://doi.org/10.1016/j.brainresbull.2006.10.028

Verbal episodic memory declines prior to diagnosis in Huntington's disease

A. C. Solomon, J. Stout, Shannon A. Johnson, et al.. (2007). Neuropsychologia. Cited 130 times. https://doi.org/10.1016/j.neuropsychologia.2006.12.015

Saccades in presymptomatic and early stages of Huntington disease

T. Blekher, Shannon A Johnson, Jeanine Marshall, et al.. (2006). Neurology. Cited 124 times. https://doi.org/10.1212/01.wnl.0000227890.87398.c1

Functional brain changes in presymptomatic Huntington's disease

Sarah A. J. Reading, Adam C. Dziorny, L. A. Peroutka, et al.. (2004). Annals of Neurology. Cited 121 times. https://doi.org/10.1002/ana.20121

Patient and caregiver quality of life in Huntington's disease

R. Ready, M. Mathews, A. Leserman, et al.. (2008). Movement Disorders. Cited 117 times. https://doi.org/10.1002/mds.21920

Morphology of the cerebral cortex in preclinical Huntington's disease.

P. Nopoulos, V. Magnotta, A. Mikos, et al.. (2007). The American journal of psychiatry. Cited 86 times. https://doi.org/10.1176/APPI.AJP.2007.06081266

Increased cortical recruitment in Huntington's disease using a Simon task

N. Georgiou‐Karistianis, A. Sritharan, M. Farrow, et al.. (2007). Neuropsychologia. Cited 82 times. https://doi.org/10.1016/j.neuropsychologia.2006.12.023

Specific psychiatric manifestations among preclinical Huntington disease mutation carriers.

Jeanine Marshall, K. White, M. Weaver, et al.. (2007). Archives of neurology. Cited 77 times. https://doi.org/10.1001/ARCHNEUR.64.1.116

Oculomotor control in asymptomatic and recently diagnosed individuals with the genetic marker for Huntington’s disease

T. Blekher, R. Yee, S. C. Kirkwood, et al.. (2003). Vision Research. Cited 77 times. https://doi.org/10.1016/j.visres.2004.06.006

Automatic detection of preclinical neurodegeneration

S. Klöppel, C. Chu, G. Tan, et al.. (2009). Neurology. Cited 68 times. https://doi.org/10.1212/01.wnl.0000341768.28646.b6

Engagement with genetic discrimination: concerns and experiences in the context of Huntington disease

Y. Bombard, E. Penziner, O. Suchowersky, et al.. (2008). European Journal of Human Genetics. Cited 67 times. https://doi.org/10.1038/sj.ejhg.5201937

Obsessive and compulsive symptoms in prediagnosed Huntington's disease.

L. Beglinger, Jane S. Paulsen, D. Watson, et al.. (2008). The Journal of clinical psychiatry. Cited 67 times. https://doi.org/10.4088/JCP.V69N1111

Evaluation of the GTRACT diffusion tensor tractography algorithm: A validation and reliability study

Peng Cheng, V. Magnotta, Dee H. Wu, et al.. (2006). NeuroImage. Cited 64 times. https://doi.org/10.1016/j.neuroimage.2006.01.028

Perceptions of discrimination among persons who have undergone predictive testing for Huntington's disease

E. Penziner, Janet K. Williams, C. Erwin, et al.. (2008). American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Cited 57 times. https://doi.org/10.1002/ajmg.b.30600

Experiences of Teens Living in the Shadow of Huntington Disease

K. Sparbel, M. Driessnack, Janet K. Williams, et al.. (2008). Journal of Genetic Counseling. Cited 54 times. https://doi.org/10.1007/s10897-008-9151-6

Caudate volume as an outcome measure in clinical trials for Huntington’s disease: a pilot study

Elizabeth H. Aylward, Elizabeth H. Aylward, Adam Rosenblatt, et al.. (2003). Brain Research Bulletin. Cited 51 times. https://doi.org/10.1016/j.brainresbull.2003.09.005

Cognitive deficits in Huntington's disease on the Repeatable Battery for the Assessment of Neuropsychological Status

K. Duff, L. Beglinger, D. Theriault, et al.. (2010). Journal of Clinical and Experimental Neuropsychology. Cited 48 times. https://doi.org/10.1080/13803390902926184

Managing genetic discrimination: Strategies used by individuals found to have the Huntington disease mutation

Y. Bombard, E. Penziner, J. Decolongon, et al.. (2007). Clinical Genetics. Cited 43 times. https://doi.org/10.1111/j.1399-0004.2007.00770.x

Predictors of diagnosis in Huntington disease

D. Langbehn, Jane S. Paulsen. (2007). Neurology. Cited 42 times. https://doi.org/10.1212/01.wnl.0000261918.90053.96

Neural bases of dysphoria in early Huntington's disease

S. Paradiso, B. Turner, Jane S. Paulsen, et al.. (2008). Psychiatry Research: Neuroimaging. Cited 40 times. https://doi.org/10.1016/j.pscychresns.2007.04.001

Are Cognitive Changes Progressive in Prediagnostic HD?

J. Stout, M. Weaver, A. C. Solomon, et al.. (2007). Cognitive and Behavioral Neurology. Cited 33 times. https://doi.org/10.1097/WNN.0b013e31815cfef8

Genetic testing and Huntington's disease: issues of employment

P. Harper, Sjef K. Gevers, G. Wert, et al.. (2004). The Lancet Neurology. Cited 32 times. https://doi.org/10.1016/S1474-4422(04)00711-2

Predict-HD and the future of therapeutic trials

E. Wild, S. Tabrizi. (2006). The Lancet Neurology. Cited 22 times. https://doi.org/10.1016/S1474-4422(06)70531-2

Cognitive impairment and dementia in basal ganglia disorders

J. Stout, Shannon A. Johnson. (2005). Current Neurology and Neuroscience Reports. Cited 19 times. https://doi.org/10.1007/S11910-005-0059-3

Semi-automated Basal Ganglia Segmentation Using Large Deformation Diffeomorphic Metric Mapping

Ali R. Khan, E. Aylward, P. Barta, et al.. (2005). Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Cited 14 times. https://doi.org/10.1007/11566465_30

Visual function in Huntington's disease patients and presymptomatic gene carriers

B. O’Donnell, Marcia A. Wilt, A. Hake, et al.. (2003). Movement Disorders. Cited 11 times. https://doi.org/10.1002/mds.10491

Is tetrabenazine safe and effective for suppressing chorea in Huntington's disease?

B. Leavitt, M. Hayden. (2006). Nature Clinical Practice Neurology. Cited 7 times. https://doi.org/10.1038/NCPNEURO0299

Monitoring reportable events and unanticipated problems: the PHAROS and PREDICT studies of Huntington disease.

C. Erwin, S. Hersch. (2007). IRB. Cited 4 times.