Jackson Heart Study (JHS) Cohort

Multiple rare alleles at LDLR and APOA5 confer risk for early-onset myocardial infarction

R. Do, N. Stitziel, H. Won, et al.. (2014). Nature. Cited 433 times. https://doi.org/10.1038/nature13917

Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene

David Reich, David Reich, Michael A. Nalls, et al.. (2009). PLoS Genetics. Cited 396 times. https://doi.org/10.1371/journal.pgen.1000360

Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium

Megan L. Grove, Bing Yu, B. Cochran, et al.. (2013). PLoS ONE. Cited 263 times. https://doi.org/10.1371/journal.pone.0068095

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.

M. Holmes, L. Lange, T. Palmer, et al.. (2014). American journal of human genetics. Cited 225 times. https://doi.org/10.1016/j.ajhg.2013.12.014

Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans.

R. Naik, V. Derebail, Morgan E. Grams, et al.. (2014). JAMA. Cited 194 times. https://doi.org/10.1001/jama.2014.15063

Admixture mapping of white cell count: genetic locus responsible for lower white blood cell count in the Health ABC and Jackson Heart studies.

M. Nalls, James G. Wilson, N. Patterson, et al.. (2008). American journal of human genetics. Cited 187 times. https://doi.org/10.1016/j.ajhg.2007.09.003

Increased Burden of Cardiovascular Disease in Carriers of APOL1 Genetic Variants

K. Ito, A. Bick, J. Flannick, et al.. (2014). Circulation Research. Cited 160 times. https://doi.org/10.1161/CIRCRESAHA.114.302347

Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts.

A. Bick, J. Flannick, K. Ito, et al.. (2012). American journal of human genetics. Cited 134 times. https://doi.org/10.1016/j.ajhg.2012.07.017

Study design for genetic analysis in the Jackson Heart Study.

James G. Wilson, C. Rotimi, L. Ekunwe, et al.. (2005). Ethnicity & disease. Cited 126 times.

Genetic Differences between the Determinants of Lipid Profile Phenotypes in African and European Americans: The Jackson Heart Study

Rahul C. Deo, D. Reich, Arti Tandon, et al.. (2009). PLoS Genetics. Cited 111 times. https://doi.org/10.1371/journal.pgen.1000342

African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts

Ching-Yu Cheng, David Reich, David Reich, et al.. (2012). PLoS ONE. Cited 75 times. https://doi.org/10.1371/journal.pone.0032840

Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans

Rahul C. Deo, James G. Wilson, Chao Xing, et al.. (2011). PLoS ONE. Cited 71 times. https://doi.org/10.1371/journal.pone.0014581

Epidemiology, heritability, and genetic linkage of C-reactive protein in African Americans (from the Jackson Heart Study).

E. Fox, E. Benjamin, D. Sarpong, et al.. (2008). The American journal of cardiology. Cited 59 times. https://doi.org/10.1016/j.amjcard.2008.05.049

Clinical Correlates and Heritability of QT Interval Duration in Blacks: The Jackson Heart Study

E. Akylbekova, R. Crow, W. Johnson, et al.. (2009). Circulation: Arrhythmia and Electrophysiology. Cited 49 times. https://doi.org/10.1161/CIRCEP.109.858894

Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease.

B. Yu, Alexander Hanbo Li, D. Muzny, et al.. (2015). Circulation: Cardiovascular Genetics. Cited 44 times. https://doi.org/10.1161/CIRCGENETICS.114.000697

Fine-Mapping in African Americans of 8 Recently Discovered Genetic Loci for Plasma Lipids: The Jackson Heart Study

M. Keebler, Rahul C. Deo, Aarti Surti, et al.. (2010). Circulation: Cardiovascular Genetics. Cited 34 times. https://doi.org/10.1161/CIRCGENETICS.109.914267

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

S. Rodríguez, Tom R. Gaunt, Yiran Guo, et al.. (2015). European Journal of Human Genetics. Cited 33 times. https://doi.org/10.1038/ejhg.2015.63

Genome-Wide Association Analysis of Plasma B–Type Natriuretic Peptide in Blacks: The Jackson Heart Study

S. Musani, E. Fox, A. Kraja, et al.. (2015). Circulation: Cardiovascular Genetics. Cited 32 times. https://doi.org/10.1161/CIRCGENETICS.114.000900

SCN5A Variation Is Associated With Electrocardiographic Traits in the Jackson Heart Study

Janina M. Jeff, K. Brown-Gentry, Sarah G Buxbaum, et al.. (2011). Circulation: Cardiovascular Genetics. Cited 28 times. https://doi.org/10.1161/CIRCGENETICS.110.958124

Gene‐centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans

Weihong Tang, M. Cushman, D. Green, et al.. (2015). American Journal of Hematology. Cited 27 times. https://doi.org/10.1002/ajh.24005

Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans.

Jin Li, L. Lange, Qing Duan, et al.. (2015). Human molecular genetics. Cited 26 times. https://doi.org/10.1093/hmg/ddu454

Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association With the Kininogen 1 and Prekallikrein Genes

W. Lieb, Ming-Huei Chen, A. Teumer, et al.. (2015). Circulation: Cardiovascular Genetics. Cited 26 times. https://doi.org/10.1161/CIRCGENETICS.114.000613

Gene-environment interaction between SCN5A-1103Y and hypokalemia influences QT interval prolongation in African Americans: the Jackson Heart Study.

E. Akylbekova, J. Payne, C. Newton‐Cheh, et al.. (2014). American heart journal. Cited 22 times. https://doi.org/10.1016/j.ahj.2013.10.009

Genetic ancestry is associated with measures of subclinical atherosclerosis in African Americans: the Jackson Heart Study.

Samson Y. Gebreab, P. Riestra, R. Khan, et al.. (2015). Arteriosclerosis, Thrombosis, & Vascular Biology. Cited 21 times. https://doi.org/10.1161/ATVBAHA.114.304855

The social context of cardiovascular disease: challenges and opportunities for the Jackson Heart Study.

David R. Williams, Jacinta P. Leavell. (2012). Ethnicity & disease. Cited 20 times.

A Common SCN5A Variant Is Associated with PR Interval and Atrial Fibrillation Among African Americans

L. Ilkhanoff, D. Arking, R. Lemaitre, et al.. (2014). Journal of Cardiovascular Electrophysiology. Cited 19 times. https://doi.org/10.1111/jce.12483

Research participants' opinions on genetic research and reasons for participation: a Jackson Heart Study focus group analysis.

Evelyn R. Walker, Cheryl R. Nelson, Donna Antoine-Lavigne, et al.. (2014). Ethnicity & disease. Cited 19 times.

Heritability of serum sodium concentration: evidence for sex- and ethnic-specific effects.

Beth Wilmot, V. S. Voruganti, Y. C. Chang, et al.. (2012). Physiological genomics. Cited 18 times. https://doi.org/10.1152/physiolgenomics.00153.2011

American Heart Association Cardiovascular Genome-Phenome Study

I. Benjamin, Nancy A Brown, G. Burke, et al.. (2015). Circulation. Cited 15 times. https://doi.org/10.1161/CIRCULATIONAHA.114.014190

Genes and environments: moving toward personalized medicine in the context of health disparities.

R. Kittles. (2012). Ethnicity & disease. Cited 15 times.

Associations of adiponectin with individual European ancestry in African Americans: the Jackson Heart Study

A. Bidulescu, S. Choudhry, S. Musani, et al.. (2014). Frontiers in Genetics. Cited 14 times. https://doi.org/10.3389/fgene.2014.00022

The Jackson Heart Study of the future.

H. Taylor. (2012). Ethnicity & disease. Cited 9 times.