<p>Myocardial infarction (MI) is a common complex disease and the leading cause of death and disability worldwide. The genetic   basis of this disease is largely unknown. It has been thought that early-onset MI events would have a substantially greater   heritability, thus making DNA collections with younger individuals desirable. More recently, genome-wide association studies   have become feasible through the development of whole genome arrays and a large catalogue of common variants reported in the   International HapMap database. This study aims to use Affymetrix genotyping platform to do a whole genome scan   in 3000 early-onset MI cases and 3000 matched controls from 6 study collection sites.</p>

STAMPEED: Myocardial Infarction Genetics Consortium (MIGen)

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

New susceptibility locus for coronary artery disease on chromosome 3q22.3

A PCSK9 missense variant associated with a reduced risk of early-onset myocardial infarction.