Discovery of Non-ETS Gene Fusions using RNA Sequencing

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Integrative genomic profiling of human prostate cancer.

B. Taylor, N. Schultz, H. Hieronymus, et al.. (2010). Cancer cell. Cited 3,593 times. https://doi.org/10.1016/j.ccr.2010.05.026

The cancer genome

M. Stratton, Peter J. Campbell, Peter J. Campbell, et al.. (2009). Nature. Cited 3,589 times. https://doi.org/10.1038/nature07943

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

T. Sjöblom, Siân Jones, L. Wood, et al.. (2006). Science. Cited 2,734 times. https://doi.org/10.1126/science.1133427

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

S. Tomlins, D. Rhodes, S. Perner, et al.. (2006). Science. Cited 2,531 times. https://doi.org/10.1016/S0022-5347(06)00096-6

The impact of translocations and gene fusions on cancer causation

F. Mitelman, B. Johansson, F. Mertens. (2007). Nature Reviews Cancer. Cited 1,374 times. https://doi.org/10.1038/nrc2091

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

G. Dalgliesh, K. Furge, C. Greenman, et al.. (2009). Nature. Cited 1,207 times. https://doi.org/10.1038/nature08672

Transcriptome Sequencing to Detect Gene Fusions in Cancer

C. Maher, Chandan Kumar-Sinha, Xuhong Cao, et al.. (2009). Nature. Cited 937 times. https://doi.org/10.1038/nature07638

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

S. Tomlins, B. Laxman, S. Dhanasekaran, et al.. (2007). Nature. Cited 890 times. https://doi.org/10.1038/nature06024

COMPLEX LANDSCAPES OF SOMATIC REARRANGEMENT IN HUMAN BREAST CANCER GENOMES

Philip J. Stephens, D. Mcbride, Meng‐Lay Lin, et al.. (2009). Nature. Cited 844 times. https://doi.org/10.1038/nature08645

A large genome center's improvements to the Illumina sequencing system

M. Quail, I. Kozarewa, Frances Smith, et al.. (2008). Nature Methods. Cited 753 times. https://doi.org/10.1038/nmeth.1270

Role of the TMPRSS2-ERG gene fusion in prostate cancer.

S. Tomlins, B. Laxman, S. Varambally, et al.. (2008). Neoplasia. Cited 714 times. https://doi.org/10.1593/NEO.07822

What is a gene, post-ENCODE? History and updated definition.

M. Gerstein, Can Bruce, J. Rozowsky, et al.. (2007). Genome research. Cited 710 times. https://doi.org/10.1101/GR.6339607

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

B. Carver, J. Tran, A. Gopalan, et al.. (2009). Nature Genetics. Cited 688 times. https://doi.org/10.1038/ng.370

Molecular characterization of human prostate carcinoma cell lines

A. van Bokhoven, M. Varella-Garcia, C. Korch, et al.. (2003). The Prostate. Cited 631 times. https://doi.org/10.1002/pros.10290

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

Chunru Lin, Liuqing Yang, Bogdan Tanasa, et al.. (2009). Cell. Cited 610 times. https://doi.org/10.1016/j.cell.2009.11.030

Recurrent gene fusions in prostate cancer

Chandan Kumar-Sinha, S. Tomlins, A. Chinnaiyan. (2008). Nature Reviews Cancer. Cited 556 times. https://doi.org/10.1038/nrc2402

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.

S. Perner, F. Demichelis, R. Beroukhim, et al.. (2006). Cancer research. Cited 549 times. https://doi.org/10.1158/0008-5472.CAN-06-1482

Chromosome translocations in multiple myeloma

P. Bergsagel, W. Kuehl. (2001). Oncogene. Cited 468 times. https://doi.org/10.1038/sj.onc.1204641

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

N. Palanisamy, Bushra Ateeq, Shanker Kalyana-Sundaram, et al.. (2010). Nature Medicine. Cited 455 times. https://doi.org/10.1038/nm.2166

Chimeric transcript discovery by paired-end transcriptome sequencing

C. Maher, N. Palanisamy, J. Brenner, et al.. (2009). Proceedings of the National Academy of Sciences. Cited 358 times. https://doi.org/10.1073/pnas.0904720106

A causal role for ERG in neoplastic transformation of prostate epithelium

O. Klezovitch, M. Risk, Ilsa M Coleman, et al.. (2008). Proceedings of the National Academy of Sciences. Cited 323 times. https://doi.org/10.1073/pnas.0711711105

Integrative analysis of the melanoma transcriptome.

M. Berger, J. Levin, K. Vijayendran, et al.. (2010). Genome research. Cited 292 times. https://doi.org/10.1101/gr.103697.109

Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

M. Yoshimoto, A. Joshua, I. W. Cunha, et al.. (2008). Modern Pathology. Cited 291 times. https://doi.org/10.1038/modpathol.2008.96

Prevalence of TMPRSS2-ERG Fusion Prostate Cancer among Men Undergoing Prostate Biopsy in the United States

J. Mosquera, R. Mehra, M. Regan, et al.. (2009). Clinical Cancer Research. Cited 241 times. https://doi.org/10.1158/1078-0432.CCR-08-2927

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.

J. Burke, M. Pattoli, K. Gregor, et al.. (2003). The Journal of biological chemistry. Cited 239 times.

Molecular sampling of prostate cancer: a dilemma for predicting disease progression

A. Sboner, F. Demichelis, Stefano Calza, et al.. (2010). BMC Medical Genomics. Cited 232 times. https://doi.org/10.1186/1755-8794-3-8

Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression

B. Han, R. Mehra, R. Lonigro, et al.. (2009). Modern Pathology. Cited 231 times. https://doi.org/10.1038/modpathol.2009.69

SLC45A3-ELK4 is a novel and frequent erythroblast transformation-specific fusion transcript in prostate cancer.

D. Rickman, D. Pflueger, Benjamin J. Moss, et al.. (2009). Cancer research. Cited 224 times. https://doi.org/10.1158/0008-5472.CAN-08-4926

Implications of chimaeric non-co-linear transcripts

T. Gingeras. (2009). Nature. Cited 220 times. https://doi.org/10.1038/nature08452

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing.

D. Pflueger, S. Terry, A. Sboner, et al.. (2011). Genome research. Cited 219 times. https://doi.org/10.1101/gr.110684.110

A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups.

S. Sulong, A. Moorman, J. Irving, et al.. (2009). Blood. Cited 210 times. https://doi.org/10.1182/blood-2008-07-166801

Correlation of reduction in MRP-1/CD9 and KAI1/CD82 expression with recurrences in breast cancer patients.

Cheng‐long Huang, N. Kohno, E. Ogawa, et al.. (1998). The American journal of pathology. Cited 208 times. https://doi.org/10.1016/S0002-9440(10)65639-8

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

L. Lam, R. Davis, J. Pierce, et al.. (2005). Clinical cancer research : an official journal of the American Association for Cancer Research. Cited 173 times.

Reduced motility related protein-1 (MRP-1/CD9) gene expression as a factor of poor prognosis in non-small cell lung cancer.

M. Higashiyama, T. Taki, Yoshiaki Ieki, et al.. (1995). Cancer research. Cited 142 times.

Effects of IKK inhibitor PS1145 on NF-kappaB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells.

A. Yemelyanov, A. Gasparian, P. Lindholm, et al.. (2006). Oncogene. Cited 124 times.

Two unique novel prostate-specific and androgen-regulated fusion partners of ETV4 in prostate cancer.

Karin G. Hermans, Anke A Bressers, H. A. van der Korput, et al.. (2008). Cancer research. Cited 114 times. https://doi.org/10.1158/0008-5472.CAN-08-0198

Pharmacologic inhibitors of IκB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo

A. Idris, H. Libouban, Hervé Nyangoga, et al.. (2009). Molecular Cancer Therapeutics. Cited 112 times. https://doi.org/10.1158/1535-7163.MCT-09-0133

Motility related protein 1 (MRP1/CD9) expression in colon cancer.

Masaki Mori, K. Mimori, T. Shiraishi, et al.. (1998). Clinical cancer research : an official journal of the American Association for Cancer Research. Cited 103 times.

Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers

H. Makkonen, M. Kauhanen, Ville Paakinaho, et al.. (2009). Nucleic Acids Research. Cited 96 times. https://doi.org/10.1093/nar/gkp352

CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer

Zhongmin Guo, J. Linn, Guojun Wu, et al.. (2004). Nature Medicine. Cited 95 times. https://doi.org/10.1038/nm1010

Oncoproteomic Analysis Reveals Co-Upregulation of RELA and STAT5 in Carboplatin Resistant Ovarian Carcinoma

N. Jinawath, Chanont Vasoontara, A. Jinawath, et al.. (2010). PLoS ONE. Cited 89 times. https://doi.org/10.1371/journal.pone.0011198

BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.

Jinming Yang, K. Amiri, J. Burke, et al.. (2006). Clinical cancer research : an official journal of the American Association for Cancer Research. Cited 78 times.

Down-Regulation of CD9 Expression during Prostate Carcinoma Progression Is Associated with CD9 mRNA Modifications

Jia-chi Wang, L. Bégin, N. Bérubé, et al.. (2007). Clinical Cancer Research. Cited 73 times. https://doi.org/10.1158/1078-0432.CCR-06-1692

Progression of cervical carcinomas is associated with down-regulation of CD9 but strong local re-expression at sites of transendothelial invasion.

G. Sauer, J. Windisch, C. Kurzeder, et al.. (2003). Clinical cancer research : an official journal of the American Association for Cancer Research. Cited 68 times.

Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer.

Guojun Wu, Zhongmin Guo, Aditi Chatterjee, et al.. (2006). Cancer research. Cited 64 times. https://doi.org/10.1158/0008-5472.CAN-06-0506

Profiling the expression pattern of GPI transamidase complex subunits in human cancer

J. Nagpal, S. Dasgupta, S. Jadallah, et al.. (2008). Modern Pathology. Cited 61 times. https://doi.org/10.1038/modpathol.2008.76

A novel gene, RSRC2, inhibits cell proliferation and affects survival in esophageal cancer patients.

Hiroki Kurehara, H. Ishiguro, M. Kimura, et al.. (2007). International journal of oncology. Cited 20 times. https://doi.org/10.3892/IJO.30.2.421
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