<p>We have developed FusionSeq to identify fusion transcripts from paired-end RNA-sequencing. FusionSeq includes filters to  remove spurious candidate fusions with artifacts such as misalignments or random pairing of transcript fragments and it  ranks candidates according to several statistics. It also has a module to identify exact sequences at breakpoint junctions.  FusionSeq detected known and novel fusions in a specially sequenced calibration data set, including 8 cancers with and  without known rearrangements.</p>

FusionSeq: Finding Fusions with Paired-End RNA-Seq

Prostatic Neoplasms study with RNA-Seq data on dbGaP (8 participants)

FusionSeq: Finding Fusions with Paired-End RNA-Seq

Description

Applying For Access

Summary