SardiNIA Medical Sequencing Discovery Project

Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits

A. Scuteri, S. Sanna, Wei-Min Chen, et al.. (2007). PLoS Genetics. Cited 1,726 times. https://doi.org/10.1371/journal.pgen.0030115

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

C. Willer, S. Sanna, A. Jackson, et al.. (2008). Nature Genetics. Cited 1,680 times. https://doi.org/10.1038/ng.76

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

M. Uda, R. Galanello, S. Sanna, et al.. (2008). Proceedings of the National Academy of Sciences. Cited 611 times. https://doi.org/10.1073/pnas.0711566105

Heritability of Cardiovascular and Personality Traits in 6,148 Sardinians

G. Pilia, Wei-Min Chen, A. Scuteri, et al.. (2006). PLoS Genetics. Cited 591 times. https://doi.org/10.1371/JOURNAL.PGEN.0020132

Common variants in the GDF5-UQCC region are associated with variation in human height

S. Sanna, A. Jackson, R. Nagaraja, et al.. (2008). Nature Genetics. Cited 423 times. https://doi.org/10.1038/ng.74

Genetic Variants Regulating Immune Cell Levels in Health and Disease

V. Orrù, M. Steri, G. Sole, et al.. (2013). Cell. Cited 347 times. https://doi.org/10.1016/j.cell.2013.08.041

The GLUT9 Gene Is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts

Siguang Li, S. Sanna, A. Maschio, et al.. (2007). PLoS Genetics. Cited 316 times. https://doi.org/10.1371/journal.pgen.0030194

Genome-wide association scan for five major dimensions of personality

A. Terracciano, S. Sanna, M. Uda, et al.. (2010). Molecular Psychiatry. Cited 293 times. https://doi.org/10.1038/mp.2008.113

Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability

S. Sanna, Bingshan Li, A. Mulas, et al.. (2011). PLoS Genetics. Cited 184 times. https://doi.org/10.1371/journal.pgen.1002198

A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation

S. Naitza, E. Porcu, M. Steri, et al.. (2012). PLoS Genetics. Cited 172 times. https://doi.org/10.1371/journal.pgen.1002480

Low-Pass DNA Sequencing of 1200 Sardinians Reconstructs European Y-Chromosome Phylogeny

P. Francalacci, L. Morelli, A. Angius, et al.. (2013). Science. Cited 155 times. https://doi.org/10.1126/science.1237947

Genome-Wide Association Scan of Trait Depression

A. Terracciano, Toshiko Tanaka, A. Sutin, et al.. (2010). Biological Psychiatry. Cited 146 times. https://doi.org/10.1016/j.biopsych.2010.06.030

Amelioration of Sardinian beta0 thalassemia by genetic modifiers.

R. Galanello, S. Sanna, L. Perseu, et al.. (2009). Blood. Cited 144 times. https://doi.org/10.1182/blood-2009-04-217901

Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.

L. Arnaud-Lopez, G. Usala, G. Ceresini, et al.. (2008). American journal of human genetics. Cited 141 times. https://doi.org/10.1016/j.ajhg.2008.04.019

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

S. Sanna, F. Busonero, A. Maschio, et al.. (2009). Human molecular genetics. Cited 138 times. https://doi.org/10.1093/hmg/ddp203

COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan

K. Tarasov, S. Sanna, A. Scuteri, et al.. (2009). Circulation: Cardiovascular Genetics. Cited 113 times. https://doi.org/10.1161/CIRCGENETICS.108.823245

BDNF Val66Met is Associated with Introversion and Interacts with 5-HTTLPR to Influence Neuroticism

A. Terracciano, Toshiko Tanaka, A. Sutin, et al.. (2010). Neuropsychopharmacology. Cited 105 times. https://doi.org/10.1038/npp.2009.213

Genetics of serum BDNF: Meta-analysis of the Val66Met and genome-wide association study

A. Terracciano, M. Piras, M. Lobina, et al.. (2013). The World Journal of Biological Psychiatry. Cited 79 times. https://doi.org/10.3109/15622975.2011.616533

Variants of the serotonin transporter gene and NEO‐PI‐R Neuroticism: No association in the BLSA and SardiNIA samples

A. Terracciano, L. Balaci, Jason Thayer, et al.. (2009). American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Cited 47 times. https://doi.org/10.1002/ajmg.b.30932

Prevalence of unknown thyroid disorders in a Sardinian cohort.

A. Delitala, M. G. Pilia, Liana Ferreli, et al.. (2014). European journal of endocrinology. Cited 46 times. https://doi.org/10.1530/EJE-14-0182

Serum free thyroxine levels are positively associated with arterial stiffness in the SardiNIA study

A. Delitala, M. Orrù, F. Filigheddu, et al.. (2015). Clinical Endocrinology. Cited 40 times. https://doi.org/10.1111/cen.12532

Prevalence of CKD and its relationship to eGFR-related genetic loci and clinical risk factors in the SardiNIA study cohort.

A. Pani, J. Bragg-Gresham, Marco Masala, et al.. (2014). Journal of the American Society of Nephrology : JASN. Cited 40 times. https://doi.org/10.1681/ASN.2013060591

Personality Traits and Circadian Blood Pressure Patterns: A 7-Year Prospective Study

A. Terracciano, James B. Strait, A. Scuteri, et al.. (2014). Psychosomatic Medicine. Cited 18 times. https://doi.org/10.1097/PSY.0000000000000035