<p>A research cohort of adult Geisinger Clinic patients was enrolled from community-based primary care clinics of the     Geisinger Health System.  Patients were eligible for enrollment if they were a primary care patient of a Geisinger Clinic     physician and were scheduled for a non-emergent clinic visit.  All participants provided written informed consent and     HIPAA authorization.  Consenting patient agreed to provide blood samples for broad biomedical research use, and permission     to access data in their Geisinger electronic medical record for research.  The enrollment rate was 90% of patients approached.     The demographics of the cohort approximate those of the Geisinger Clinic outpatient population.  Research blood samples were     collected during an outpatient clinical phlebotomy encounter.  Research blood samples are coded and stored in a central biorepository.     Samples are linkable to clinical data in a de-identified manner for research via an IRB-approved data broker process.  For genomic     analysis, DNA is extracted from EDTA-anticoagulated whole blood.  For the initial eMERGE Geisinger eGenomic Medicine (GeM)     genotyping project, a subset of 1,232 unique samples were genotyped using Illumina HumanOmniExpress-12 v1.0 arrays, and used     as population controls for other Geisinger Clinic case cohorts, including abdominal aortic aneurysm and gastric bypass surgery cases.     These samples were selected from a larger subset of approximately 6,000 MyCode DNA samples using a partial matching algorithm     that included age, sex, and body mass index as variables.</p>

Geisinger eMERGE - MyCode Project

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