Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy.
V. Dolan, M. Murphy, D. Sadlier, et al.. (2005). American journal of kidney diseases : the official journal of the National Kidney Foundation. Cited 147 times. https://doi.org/10.1053/J.AJKD.2005.03.014High Glucose-altered Gene Expression in Mesangial Cells
M. Clarkson, M. Murphy, S. Gupta, et al.. (2002). The Journal of Biological Chemistry. Cited 96 times. https://doi.org/10.1074/jbc.M109172200Allelic Depletion of grem1 Attenuates Diabetic Kidney Disease
S. Roxburgh, J. Kattla, S. Curran, et al.. (2009). Diabetes. Cited 77 times. https://doi.org/10.2337/db08-1365CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: Implications for the pathogenesis of diabetic nephropathy
Brian Rooney, Helen C O'Donovan, Andrew Gaffney, et al.. (2011). FEBS Letters. Cited 75 times. https://doi.org/10.1016/j.febslet.2011.01.004Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization
J. Crean, F. Furlong, D. Finlay, et al.. (2004). The FASEB Journal. Cited 72 times. https://doi.org/10.1096/fj.04-1546fjeGenetic Examination of SETD7 and SUV39H1/H2 Methyltransferases and the Risk of Diabetes Complications in Patients With Type 1 Diabetes
A. Syreeni, A. El-Osta, C. Forsblom, et al.. (2011). Diabetes. Cited 63 times. https://doi.org/10.2337/db11-0073IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.
M. Murphy, N. Docherty, B. Griffin, et al.. (2008). Journal of the American Society of Nephrology : JASN. Cited 62 times. https://doi.org/10.1681/ASN.2007101080A GREM1 gene variant associates with diabetic nephropathy.
A. McKnight, C. Patterson, K. Pettigrew, et al.. (2010). Journal of the American Society of Nephrology : JASN. Cited 47 times. https://doi.org/10.1681/ASN.2009070773Regulation and consequences of differential gene expression in diabetic kidney disease.
M. Murphy, J. Crean, D. Brazil, et al.. (2008). Biochemical Society transactions. Cited 36 times. https://doi.org/10.1042/BST0360941A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.
Rosalind J L Martin, A. McKnight, C. Patterson, et al.. (2010). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Cited 36 times. https://doi.org/10.1093/ndt/gfp515Comparative analysis of DNA methylation profiles in peripheral blood leukocytes versus lymphoblastoid cell lines
E. Brennan, M. Ehrich, D. Brazil, et al.. (2009). Epigenetics. Cited 34 times. https://doi.org/10.4161/epi.4.3.8793DNA methylation profiling in cell models of diabetic nephropathy
E. Brennan, M. Ehrich, Helen C O'Donovan, et al.. (2010). Epigenetics. Cited 32 times. https://doi.org/10.4161/epi.5.5.12077Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B‐mediated phosphorylation and cytoplasmic translocation of p27Kip‐1
J. Crean, F. Furlong, D. Mitchell, et al.. (2006). The FASEB Journal. Cited 30 times. https://doi.org/10.1096/fj.05-5010fjeAssociation of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus.
B. He, Anne-May Österholm, Anna Hoverfält, et al.. (2009). American journal of human genetics. Cited 29 times. https://doi.org/10.1016/j.ajhg.2008.11.012Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in Type 1 diabetes mellitus
D. Currie, A. McKnight, C. Patterson, et al.. (2010). Diabetic Medicine. Cited 24 times. https://doi.org/10.1111/j.1464-5491.2010.03097.xInvestigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus
A. J. McKnight, A. Woodman, M. Parkkonen, et al.. (2009). Diabetologia. Cited 21 times. https://doi.org/10.1007/s00125-009-1281-3Genetic Polymorphisms in Nitric Oxide Synthase 3 Gene and Implications for Kidney Disease: A Meta-Analysis
A. McKnight, C. Patterson, N. Sandholm, et al.. (2010). American Journal of Nephrology. Cited 20 times. https://doi.org/10.1159/000321340Targeted genome-wide investigation identifies novel SNPs associated with diabetic nephropathy
A. McKnight, D. Currie, C. Patterson, et al.. (2009). The HUGO Journal. Cited 19 times. https://doi.org/10.1007/s11568-010-9133-2The TGF-beta 1 gene codon 10 polymorphism contributes to the genetic predisposition to nephropathy in Type 1 diabetes.
A. Patel, W. Scott, P. Lympany, et al.. (2005). Diabetic medicine : a journal of the British Diabetic Association. Cited 16 times.Resequencing of the CCL5 and CCR5 genes and investigation of variants for association with diabetic nephropathy
K. Pettigrew, A. McKnight, C. Patterson, et al.. (2010). Journal of Human Genetics. Cited 16 times. https://doi.org/10.1038/jhg.2010.15Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy
D. Savage, C. Patterson, P. Deloukas, et al.. (2008). Diabetologia. Cited 15 times. https://doi.org/10.1007/s00125-008-1142-5Investigation of the association of BMP gene variants with nephropathy in Type 1 diabetes mellitus
A. J. McKnight, K. A. Pettigrew, C. Patterson, et al.. (2010). Diabetic Medicine. Cited 12 times. https://doi.org/10.1111/j.1464-5491.2010.02976.xGenetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy.
A. McKnight, A. Maxwell, D. Fogarty, et al.. (2009). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. Cited 9 times. https://doi.org/10.1093/ndt/gfp015Investigation of Adducin 2 (beta) DNA polymorphisms in genetic predisposition to diabetic nephropathy in Type 1 diabetes
D. Currie, A. P. Maxwell, D. Sadlier, et al.. (2008). Diabetic Medicine. Cited 8 times. https://doi.org/10.1111/j.1464-5491.2008.02511.xNo support for association of protein kinase C, beta 1 (PRKCB1) gene promoter polymorphisms c.–1504C>T and c.–546C>G with diabetic nephropathy in Type 1 diabetes
Kerry A. Pettigrew, A. McKnight, Rosalind J L Martin, et al.. (2008). Diabetic Medicine. Cited 5 times. https://doi.org/10.1111/j.1464-5491.2008.02540.xReplication studies based on findings from a genome-wide DNA microsatellite screen in diabetic nephropathy.
R. J. Martin, A. Maxwell, C. Patterson, et al.. (2009). Diabetes & metabolism. Cited 1 times. https://doi.org/10.1016/j.diabet.2009.03.002