NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (CARDIA)

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Anthropometry (4)

Biomarkers (28)

  • ESP_basophils - Basophils in absolute numbers at designated visit (may not be baseline) (phv00190611.v1.p2)
  • ESP_crp - C-reactive protein level in mg/L at designated visit (may not be baseline) (phv00190591.v1.p2)
  • ESP_dbp_baseline - Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg (phv00190575.v1.p2)
  • ESP_eosinophils - Eosinophils in absolute numbers at designated visit (may not be baseline). (phv00190610.v1.p2)
  • ESP_factorvii - Factor VII level in % at designated visit (may not be baseline) (phv00190585.v1.p2)
  • ESP_factorviii - Factor VIII level in % at designated visit (may not be baseline) (phv00190587.v1.p2)
  • ESP_fastinsulin_baseline - Blood fasting glucose at baseline in mg/dL (phv00190582.v1.p2)
  • ESP_fibrinogen - Fibrinogen level in mg/dL at first designated visit (may not be baseline) (phv00190583.v1.p2)
  • ESP_hdl_baseline - HDL level in mg/dL at baseline (phv00190570.v1.p2)
  • ESP_hematocrit - Hematocrit at designated visit (may not be baseline) in % (phv00190601.v1.p2)
  • ESP_hemoglobin - Hemoglobin at designated visit (may not be baseline) in g/dl (phv00190599.v1.p2)
  • ESP_icam1 - ICAM1 level in ng/mL at designated visit (may not be baseline) (phv00190593.v1.p2)
  • ESP_ldl_baseline - Baseline calculated LDL in mg/dL (missing where trigs>400) (phv00190569.v1.p2)
  • ESP_lymphocytes - Lymphocytes in absolute numbers at designated visit (may not be baseline). (phv00190609.v1.p2)
  • ESP_monocytes - Monocytes in absolute numbers at designated visit (may not be baseline). (phv00190608.v1.p2)
  • ESP_neutrophils - Neutrophils in absolute numbers at designated visit (may not be baseline). (phv00190607.v1.p2)
  • ESP_platelet_count - Platelet count at designated visit (may not be baseline) in x 1000/cubic mm (phv00190603.v1.p2)
  • ESP_pselectin - P-selectin level at designated visit (may not be baseline) (phv00190595.v1.p2)
  • ESP_red_blood_count - Red blood cell count in million cells per microliter at designated visit (may not be baseline) (phv00190605.v1.p2)
  • ESP_sbp_baseline - Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg (phv00190574.v1.p2)
  • ESP_serum_creatinine - Serum creatinine in mg/dL (phv00190621.v1.p2)
  • ESP_totchol_baseline - Total cholesterol at baseline in mg/dL (phv00190572.v1.p2)
  • ESP_trigs_baseline - Triglycerides at baseline in mg/dL (phv00190571.v1.p2)
  • ESP_uric_acid - Uric acid in mg/dL (phv00190615.v1.p2)
  • ESP_urinary_albumin - Raw urinary albumin. (phv00190617.v1.p2)
  • ESP_urinary_creatinine - Raw urinary creatinine in mg/dL (phv00190619.v1.p2)
  • ESP_vwf - VWF level in % at designated visit (may not be baseline) (phv00190589.v1.p2)
  • ESP_wbc - White blood count in x1,000/cubic mm at designated visit (may not be baseline) (phv00190597.v1.p2)

Demographics (16)

  • ESP_age_at_crp - Age in years at CRP measurement (phv00190592.v1.p2)
  • ESP_age_at_hematocrit - Age in years at hematocrit measurement (phv00190602.v1.p2)
  • ESP_age_at_hemoglobin - Age in years at hemoglobin measurement (phv00190600.v1.p2)
  • ESP_age_at_icam1 - Age in years at ICAM1 measurement (phv00190594.v1.p2)
  • ESP_age_at_platelet_count - Age in years at platelet count measurement (phv00190604.v1.p2)
  • ESP_age_at_pselectin - Age in years at P-selectin measurement (phv00190596.v1.p2)
  • ESP_age_at_rbc - Age in years at red blood cell count measurement (phv00190606.v1.p2)
  • ESP_age_at_serum_creatinine - Age at serum creatinine measurement (phv00190622.v1.p2)
  • ESP_age_at_uric_acid - Age in years at uric acid measurement (phv00190616.v1.p2)
  • ESP_age_at_urinary_albumin - Age in years at urinary albumin measurement (phv00190618.v1.p2)
  • ESP_age_at_urinary_creatinine - Age in years at urinary creatinine measurement (phv00190620.v1.p2)
  • ESP_age_at_vwf - Age in years at visit of hemostatic factors measurement (phv00190590.v1.p2)
  • ESP_age_at_wbc - Age in years at WBC measurement (phv00190598.v1.p2)
  • ESP_age_baseline - Age in years at baseline (phv00190560.v1.p2)
  • ESP_age_secondary_blood_counts - Age in years at secondary blood count measurements (MCV, RBC, Neutrophils, Monocytes, Lymphocytes, Eosinophils, Basophils) (phv00190612.v1.p2)
  • ESP_sex_selfreport - Values: Male; Female (phv00190558.v1.p2)

Disease Events (9)

  • ESP_asthma_ever - Asthma ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00190624.v1.p2)
  • ESP_chronic_bronchitis_ever - Chronic bronchitis ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00190625.v1.p2)
  • ESP_copd_ever - COPD ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00190627.v1.p2)
  • ESP_emphysema_ever - Emphysema ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00190626.v1.p2)
  • ESP_gout - May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study. (phv00190623.v1.p2)
  • ESP_htn_status_baseline - Physician diagnosed hypertension status at baseline (0/1) (phv00190576.v1.p2)
  • ESP_mi_baseline - MI status at baseline (0/1) (phv00190561.v1.p2)
  • ESP_pneumonia_ever - Pneumonia ever diagnosed (0/1), assessed at baseline visit (only for HeartGO and WHISP) (phv00190628.v1.p2)
  • ESP_t2diabetes_baseline - Diabetes status at baseline (0/1) (phv00190564.v1.p2)

Geography (1)

  • ESP_study_site_or_subcohort - Clinic or field center within cohort (phv00190559.v1.p2)

Imaging (1)

  • ESP_cac_agatston_score - Coronary artery calcium Agatston total score (phv00190613.v1.p2)

Medications (2)

  • ESP_htn_med_baseline - Hypertension med status (any) at baseline (0/1) (phv00190577.v1.p2)
  • ESP_lipid_med_baseline - Any lipid lowering med (statin or other) at baseline (phv00190573.v1.p2)

Race and Ethnicity (1)

Reproductive Health (1)

Respiratory (2)

  • ESP_fev1_first_avail_visit - FEV1 measurement at the first available visit (only for HeartGO) (phv00190629.v1.p2)
  • ESP_fvc_first_avail_visit - FVC measurement at the first available visit (only for HeartGO) (phv00190630.v1.p2)

Study Administration (2)

  • ESP_age_at_cac - Age in years at CAC Agatston score measurement (phv00190614.v1.p2)
  • ESP_frs_chdprob_baseline - Framingham Risk Score predicted prob. calculated at baseline (was not calculated for those with baseline history of MI) (phv00190562.v1.p2)

Substance Use (2)

  • ESP_current_smoker_baseline - Current smoking status at baseline (0/1) (phv00190578.v1.p2)
  • ESP_former_smoker_baseline - Former smoking status at baseline (0/1) (phv00190579.v1.p2)

Other (17)