National Heart Lung and Blood Institute (NHLBI) GO-ESP: Heart Cohorts Component of the Exome Sequencing Project (JHS)
Anthropometry (4)
- ESP_bmi_baseline - Baseline BMI in kg/m2 (phv00165335.v3.p2)
- ESP_height_baseline - Standing height in centimeters at baseline (phv00165340.v3.p2)
- ESP_waist_baseline - Waist in centimeters at baseline (phv00165338.v3.p2)
- ESP_weight_baseline - Weight in kilograms at baseline (phv00165337.v3.p2)
Biomarkers (30)
- ESP_avblock2_at_ekg - Second degree AV block (phv00165414.v3.p2)
- ESP_avblock3_at_ekg - Third degree AV block (phv00165415.v3.p2)
- ESP_basophils - Basophils in absolute numbers at designated visit (may not be baseline) (phv00165396.v3.p2)
- ESP_crp - C-reactive protein level in mg/L at designated visit (may not be baseline) (phv00165372.v3.p2)
- ESP_dbp_baseline - Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg (phv00165347.v3.p2)
- ESP_ekg_hr - HR interval from EKG at designated visit (may not be baseline) (phv00165410.v3.p2)
- ESP_ekg_pr - PR interval from EKG at designated visit (may not be baseline) (phv00165409.v3.p2)
- ESP_ekg_qrs - QRS interval from EKG at designated visit (may not be baseline) (phv00165406.v3.p2)
- ESP_ekg_qt - QT interval from EKG at designated visit (may not be baseline) (phv00165408.v3.p2)
- ESP_eosinophils - Eosinophils in absolute numbers at designated visit (may not be baseline). (phv00165395.v3.p2)
- ESP_fastinsulin_baseline - Blood fasting glucose at baseline in mg/dL (phv00165362.v3.p2)
- ESP_hdl_baseline - HDL level in mg/dL at baseline (phv00165342.v3.p2)
- ESP_hematocrit - Hematocrit at designated visit (may not be baseline) in % (phv00165384.v3.p2)
- ESP_hemoglobin - Hemoglobin at designated visit (may not be baseline) in g/dl (phv00165382.v3.p2)
- ESP_ldl_baseline - Baseline calculated LDL in mg/dL (missing where trigs>400) (phv00165341.v3.p2)
- ESP_lymphocytes - Lymphocytes in absolute numbers at designated visit (may not be baseline). (phv00165394.v3.p2)
- ESP_mean_corpuscular_volume - Mean corpuscular volume in femtoliters at designated visit (may not be baseline) (phv00165388.v3.p2)
- ESP_monocytes - Monocytes in absolute numbers at designated visit (may not be baseline). (phv00165393.v3.p2)
- ESP_neutrophils - Neutrophils in absolute numbers at designated visit (may not be baseline). (phv00165392.v3.p2)
- ESP_platelet_count - Platelet count at designated visit (may not be baseline) in x 1000/cubic mm (phv00165386.v3.p2)
- ESP_red_blood_count - Red blood cell count in million cells per microliter at designated visit (may not be baseline) (phv00165390.v3.p2)
- ESP_sbp_baseline - Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg (phv00165346.v3.p2)
- ESP_serum_creatinine - Serum creatinine in mg/dL (phv00181295.v2.p2)
- ESP_totchol_baseline - Total cholesterol at baseline in mg/dL (phv00165344.v3.p2)
- ESP_trigs_baseline - Triglycerides at baseline in mg/dL (phv00165343.v3.p2)
- ESP_uric_acid - Uric acid in mg/dL (phv00165426.v3.p2)
- ESP_urinary_albumin - Raw urinary albumin. (Note: these are in original study units and not harmonized across studies) (phv00165428.v3.p2)
- ESP_urinary_creatinine - Raw urinary creatinine in mg/dL (phv00165430.v3.p2)
- ESP_wbc - White blood count in x1,000/cubic mm at designated visit (may not be baseline) (phv00165380.v3.p2)
- ESP_wpw_at_ekg - Wolff-Parkinson-White pattern (phv00165413.v3.p2)
Demographics (20)
- ESP_age_at_ABI - Age in years at ABI measurement (phv00181294.v2.p2)
- ESP_age_at_cac - Age in years at CAC Agatston score measurement (phv00165401.v3.p2)
- ESP_age_at_crp - Age in years at CRP measurement (phv00165373.v3.p2)
- ESP_age_at_ekg - Age in years at EKG measurement (phv00165423.v3.p2)
- ESP_age_at_hematocrit - Age in years at hematocrit measurement (phv00165385.v3.p2)
- ESP_age_at_hemoglobin - Age in years at hemoglobin measurement (phv00165383.v3.p2)
- ESP_age_at_imt - Age in years at IMT measurement (phv00165405.v3.p2)
- ESP_age_at_mcv - Age in years at mean corpuscular volume measurement (phv00165389.v3.p2)
- ESP_age_at_menarche - Age in years at menarche (phv00165357.v3.p2)
- ESP_age_at_menopause - Age in years at menopause (phv00181288.v2.p2)
- ESP_age_at_platelet_count - Age in years at platelet count measurement (phv00165387.v3.p2)
- ESP_age_at_rbc - Age in years at red blood cell count measurement (phv00165391.v3.p2)
- ESP_age_at_serum_creatinine - Age at serum creatinine measurement (phv00181296.v2.p2)
- ESP_age_at_uric_acid - Age in years at uric acid measurement (phv00165427.v3.p2)
- ESP_age_at_urinary_albumin - Age in years at urinary albumin measurement (phv00165429.v3.p2)
- ESP_age_at_urinary_creatinine - Age in years at urinary creatinine measurement (phv00165431.v3.p2)
- ESP_age_at_wbc - Age in years at WBC measurement (phv00165381.v3.p2)
- ESP_age_baseline - Age in years at baseline (phv00165330.v3.p2)
- ESP_age_secondary_blood_counts - Age in years at secondary blood count measurements (MCV, RBC, Neutrophils, Monocytes, Lymphocytes, Eosinophils, Basophils) (phv00181291.v2.p2)
- ESP_sex_selfreport - Sex (phv00181285.v2.p2)
Disease Events (9)
- ESP_asthma_ever - Asthma ever diagnosed (phv00181297.v2.p2)
- ESP_cabg_baseline - Baseline CABG status (phv00165399.v3.p2)
- ESP_copd_ever - COPD ever diagnosed (phv00181298.v2.p2)
- ESP_htn_status_baseline - Physician diagnosed hypertension status at baseline (phv00165348.v3.p2)
- ESP_mi_baseline - MI status at baseline (phv00165331.v3.p2)
- ESP_pad - Baseline peripheral artery disease status (phv00181292.v2.p2)
- ESP_stroke_baseline - Stroke status at baseline (phv00165350.v3.p2)
- ESP_stroke_famhx_baseline - Family history (first degree relatives) of stroke at baseline (phv00165354.v3.p2)
- ESP_t2diabetes_baseline - Diabetes status at baseline (phv00165336.v3.p2)
Imaging (4)
- ESP_cac_agatston_score - Coronary artery calcium Agatston total score (phv00165400.v3.p2)
- ESP_imt_anyplaque - Presence of any plaque, as determined by IMT at designated visit (may not be baseline) (phv00165404.v3.p2)
- ESP_imt_meanmean_farwall_cca - Average far wall thickness of the right and left common carotid mean IMT values, using as many views as are available for a given study (phv00165402.v3.p2)
- ESP_imt_meanmean_farwall_ica - Average far wall thickness of the right and left internal carotid maximum IMT values, using as many views as are available for a given study (phv00165403.v3.p2)
Medications (3)
- ESP_htn_med_baseline - Hypertension med status (any) at baseline (phv00165349.v3.p2)
- ESP_lipid_med_baseline - Any lipid lowering med (statin or other) at baseline (phv00165345.v3.p2)
- ESP_t2d_med_baseline - Baseline Type 2 diabetes medication status (phv00181286.v2.p2)
Race and Ethnicity (1)
- ESP_race_selfreport - Self report race (phv00181284.v2.p2)
Reproductive Health (3)
- ESP_hormone_replacement_baseline - Indicator (phv00181290.v2.p2)
- ESP_menopause_status_baseline - Baseline menopause status (phv00181287.v2.p2)
- ESP_surgical_menopause - Indicator (phv00181289.v2.p2)
Respiratory (2)
- ESP_fev1_first_avail_visit - FEV1 measurement at the first available visit (only for HeartGO) (phv00181299.v2.p2)
- ESP_fvc_first_avail_visit - FVC measurement at the first available visit (only for HeartGO) (phv00181300.v2.p2)
Study Administration (1)
- ESP_frs_chdprob_baseline - Framingham Risk Score predicted prob. calculated at baseline (was not calculated for those with baseline history of MI) (phv00165334.v3.p2)
Substance Use (2)
- ESP_current_smoker_baseline - Current smoking status at baseline (phv00165355.v3.p2)
- ESP_former_smoker_baseline - Former smoking status at baseline (phv00165356.v3.p2)
Other (13)
- ANALYTE_TYPE - Type of analyte (phv00181305.v1.p2)
- BODY_SITE - Body site or tissue that sample is from (phv00181304.v1.p2)
- ESP_ABI_resids_from_CARe - Residuals for ankle brachial index (ABI), calculated in CARe (phv00181293.v2.p2)
- ESP_Cohort - Cohort name (phv00165322.v3.p2)
- ESP_fastglucose_baseline - Blood fasting insulin at baseline in uU/mL. (Note that there are some extreme outliers) (phv00165363.v3.p2)
- ESP_lung_function_visit - The visit that lung function measurements were taken (phv00181301.v2.p2)
- ESP_phenotype - ESP Phenotype group (phenotype that the sample was selected to be sequenced for) (phv00165324.v3.p2)
- ESP_phenotype - ESP Phenotype group [phenotype that the sample was selected to be sequenced for] (phv00181303.v1.p2)
- IS_TUMOR - Indicator of whether sample from tumor (phv00181306.v1.p2)
- SAMPLE_ID - Sample ID (phv00181302.v2.p2)
- Sequence_center - Indicates where the sample was sequence at (phv00181282.v2.p2)
- SUBJECT_ID - SUBJECT_ID (phv00165323.v3.p2)
- Target - Indicates target capture used in sequencing (phv00181283.v2.p2)