Chronic Renal Insufficiency Cohort (CRIC) - GWAS

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Anthropometry (5)

BMI - Body Mass Index (kg/m^2) (phv00173257.v2.p2)
BSA - Calculated BSA (md^2) (phv00173258.v2.p2)
HEIGHT - Height (cm) (phv00173255.v2.p2)
WAIST - Waist Circumference (cm) (phv00173259.v2.p2)
WEIGHT - Weight (kg) (phv00173256.v2.p2)

Biomarkers (42)

AFIB - Atrial fibrillation or heart arrhythmia (Yes/Not Yes) (phv00173250.v2.p2)
ALANINE_AMINOTRANSFE - Alanine Aminotransfe (U/L) (phv00173178.v2.p2)
ALBUMINURIA - Urine Albumin (4 Levels) (phv00543745.v1.p2)
ALKALINE_PHOSPHATASE - Alkaline Phosphatase (U/L) (phv00173180.v2.p2)
ASPARTATE_AMINOTRANS - Aspartate Aminotrans (U/L) (phv00173181.v2.p2)
CBCHEMOGLOBIN - CBC Hemoglobin (g/dL) (phv00173264.v2.p2)
CO2 - CO2 (mmol/L) (phv00173240.v2.p2)
CREATININE_SERUM - Creatinine Serum (mg/dL) (phv00173192.v2.p2)
DIASTOLIC - Diastolic BP (mmHg) (phv00173261.v2.p2)
EGFR_CKD_EPI - EGFR - CKD EPI Equation (ml/min/1.73m^2) (phv00543747.v1.p2)
EGFR_CRIC - EGFR - CRIC Equation (ml/min/1.73m^2) (phv00543753.v1.p2)
EGFR_ROCHE - EGFR - ROCHE or MDRD Equation (ml/min/1.73m^2) (phv00173270.v2.p2)
GLUCOSE - Glucose (mg/dL) (phv00173184.v2.p2)
HDL - High-density Lipoprotein (mg/dL) (phv00173175.v2.p2)
HEMATOCRIT - CBC Hematocrit(%) (phv00173265.v2.p2)
HEMOGLOBIN_A1C - Hemoglobin A1C (%) (phv00543731.v1.p2)
LDL - Low-density Lipoprotein (mg/dL) (phv00173176.v2.p2)
MAP - Mean Arterial Pressure (phv00173262.v2.p2)
PCR_24HRURINE - Urinary Protein to Creatinine Ratio from 24-Hr Urine Test (phv00543744.v1.p2)
PCR_SPOT - Urine Protein/Creatinine Ratio from spot sample (phv00543754.v1.p2)
PCR_URINE_COMBINED - Urine Protein/Creatinine Ratio, 24Hour and Spot measure combined (phv00543755.v1.p2)
PHOSPHATE_CALIBRATED - Calibrated Phosphate (mg/dL) (phv00543741.v1.p2)
POTASSIUM - Potassium (mmol/L) (phv00173187.v2.p2)
PULSE - Seated pulse measure (beats/min) (phv00173263.v2.p2)
SCR_ROCHE - Roche Adjusted Serum Creatinine (mg/dL) (phv00173269.v2.p2)
SERUM_ALBUMIN - Serum Albumin (g/dL) (phv00173179.v2.p2)
SERUM_UREA_NITROGEN - Serum Urea Nitrogen (mg/dL) (phv00173191.v2.p2)
SODIUM - Sodium (mmol/L) (phv00173188.v2.p2)
SYSTOLIC - Systolic BP (mmHg) (phv00173260.v2.p2)
TC - Total Cholesterol (phv00173174.v2.p2)
TG - Triglycerides (phv00173173.v2.p2)
TOTAL_BILIRUBIN - Total Bilirubin (mg/dL) (phv00173189.v2.p2)
TOTAL_PROTEIN - Total Protein (g/dL) (phv00173190.v2.p2)
UACRATIO - UAlb/UCreat ug/mg (phv00543746.v1.p2)
UALBUMIN24H - 24H Urine Albumin (g/24H) (phv00173267.v2.p2)
UCREATININE24H - 24H Urine Creatinine (g/24H) (phv00173268.v2.p2)
UPROTEIN24H - 24H Urine Protein (g/24H) (phv00173266.v2.p2)
URINE_ALBUMIN - Urine Albumin Concentration (mg/L) (phv00543734.v1.p2)
URINE_CREATININE - Urine Creatinine Concentration from 24-Hour Urine (mg/dL) (phv00543735.v1.p2)
URINE_CREATININE_R - Urine Creatinine Concentration from Random-Spot Urine (mg/dL) (phv00543736.v1.p2)
URINE_PROTEIN_MG_DL - Urine Protein Concentration from 24-Hour Urine (mg/dL) (phv00543732.v1.p2)
UTP_SELECTED_R - Urine Protein Concentration from Random-Spot Urine (mg/dL) (phv00543733.v1.p2)

Demographics (4)

AGE_INTEGER - Age (years) rounded down to the nearest integer (phv00173242.v2.p2)
COLLECTION_AGE - Age sample was collected (phv00543764.v1.p2)
SEX - Sex (1=Male, 2=Female) (phv00173280.v2.p2)
SEX - Biological sex (phv00543726.v1.p2)

Disease Events (14)

ANYCVD - Cardio-Vascular Disease (Yes/Not Yes) (phv00173249.v2.p2)
ARTHRITIS - History of Rheumatoid Arthritis (phv00173277.v2.p2)
ASTHMA - History of Asthma or Reactive Airway Disease (phv00173276.v2.p2)
CHF - Congestive Heart Failure (Yes/Not Yes) (phv00173247.v2.p2)
COPD - History of Chronic Obstructive Pulmonary Disease (emphysema) (phv00173278.v2.p2)
DIABETES - Diabetic Status (phv00543752.v1.p2)
DIABETES_AT_BASELINE - Diabetes at baseline (phv00173288.v2.p2)
FAMILYCAD - Family History of CAD (Yes/Not Yes) (phv00173289.v2.p2)
HYPERTENSION - Hypertension (y/n) (phv00543743.v1.p2)
MIREVASC - MI/Prior revascularization (Yes/Not Yes) (phv00173245.v2.p2)
PVD - Peripheral Vascular Disease (Yes/Not Yes) (phv00173246.v2.p2)
RIGHTABI - Right Ankle Brachial Index (phv00173252.v2.p2)
SA_CHF_D - CHF Definite Status (phv00543756.v1.p2)
SA_DEATH - Death Status (phv00543758.v1.p2)

Environment (2)

LEFTABI - Left Ankle Brachial Index (phv00173253.v2.p2)
LOWABI - Lowest Ankle Brachial Index (phv00173254.v2.p2)

General Health (3)

KDQOL_BURDEN - KDQOL: Burden of Kidney Disease (phv00543737.v1.p2)
KDQOL_EFFECTS - KDQOL: Effects of Kidney Disease (phv00543739.v1.p2)
KDQOL_SYMPTOMS - KDQOL: Symptoms/Problems List (phv00543738.v1.p2)

Medications (49)

ACE_INH - Medication Indicator: ACE Inhibitors (phv00173193.v2.p2)
ACEARB - Medication Indicator: ACE Inhibitors or ARBs (phv00173273.v2.p2)
ACTIVE_VITD - Medication Indicator: Active Vitamin D (phv00173212.v2.p2)
ALLOPURINOL - Medication Indicator: Allopurinol (phv00173229.v2.p2)
ALPHA_GLUCO_INH - Medication Indicator: Alpha Glucosidase Inhibitors (phv00173215.v2.p2)
ALPHA2AG - Medication Indicator: Alpha 2 Agonists (phv00173194.v2.p2)
ALPHABLK - Medication Indicator: Alpha Blockers (phv00173195.v2.p2)
ANGIOBLK - Medication Indicator: Angiotensin Receptor Blockers (phv00173196.v2.p2)
ANTIDEPRESSANT - Medication Indicator: Antidepressants (phv00173233.v2.p2)
ANTIDIABETES - Medication Indicator: Anti-Diabetes (phv00173197.v2.p2)
ANTIEPILEPTICS - Medication Indicator: Anti-Epileptics (phv00173227.v2.p2)
ANTIPLATELET - Medication Indicator: Antiplatelet Drugs (phv00173198.v2.p2)
ANXIOLYTICS - Medication Indicator: Anxiolytics (phv00173199.v2.p2)
ASPIRIN - Medication Indicator: Aspirin (phv00173234.v2.p2)
BETABLK - Medication Indicator: Beta Blockers (phv00173200.v2.p2)
BIGUANIDE - Medication Indicator: Biguanides (phv00173214.v2.p2)
BILESEQUESTRANTS - Medication Indicator: Bilesequestrants (phv00173231.v2.p2)
BISPHOSPHONATES - Medication Indicator: Bisphosphonates (phv00173224.v2.p2)
BONERI - Medication Indicator: Bone Reabsorption Inhibitors (phv00173223.v2.p2)
CABLK - Medication Indicator: Calcium Channel Blockers (phv00173201.v2.p2)
CALC_PHOSBINDERS1 - Medication Indicator: Calcium-Containing Phosphate Binders (phv00173235.v2.p2)
CALCIFEROLS - Medication Indicator: Calciferols (phv00173237.v2.p2)
CALCIUM - Calcium (mg/dL) (phv00173182.v2.p2)
CHLORIDE - Chloride (mmol/L) (phv00173183.v2.p2)
CORONARY - Medication Indicator: Coronary Vasodilators (phv00173202.v2.p2)
DIGOXIN - Medication Indicator: Digoxin (phv00173230.v2.p2)
DIURETIC - Medication Indicator: Diuretics (all) (phv00173203.v2.p2)
DPP4 - Medication Indicator: DPP4 Inhibitors (phv00173218.v2.p2)
HEPARIN - Medication Indicator: Heparins (phv00173228.v2.p2)
INSULIN - Medication Indicator: Insulin (phv00173204.v2.p2)
KSPARE_DIURETIC - Medication Indicator: Potassium Sparing Diuretics (phv00173205.v2.p2)
LIPID - Medication Indicator: Lipid-Lowering Drugs (phv00173206.v2.p2)
LOOP_DIURETIC - Medication Indicator: Loop Diuretics (phv00173207.v2.p2)
MEGLITINIDE - Medication Indicator: Meglitinides (phv00173217.v2.p2)
NBPCLASS - # Anti-HT Drug Classes Capped at 4 (phv00173272.v2.p2)
NBPDRUGS - # Anti-HT Drug Classes (phv00173271.v2.p2)
NON_CALC_PHOSBINDERS - Medication Indicator: Non-Calcium-Containing Phosphate Binders (phv00173232.v2.p2)
NON_SEL_SRI - Medication Indicator: Non-Selective SRIs (phv00173208.v2.p2)
NSAID - Medication Indicator: NSAIDs (phv00173221.v2.p2)
OTHER_LIPID - Medication Indicator: Lipid-Lowering Drugs (not statins) (phv00173220.v2.p2)
PREDNISONE - Medication Indicator: Prednisone (phv00173236.v2.p2)
SERMS - Medication Indicator: SERMs (phv00173225.v2.p2)
SSRI - Medication Indicator: Selective SRIs (phv00173209.v2.p2)
STATINS - Medication Indicator: Statins (phv00173219.v2.p2)
STEROIDS - Medication Indicator: Steroids (phv00173222.v2.p2)
SULFONYLUREA - Medication Indicator: Sulfonylureas (phv00173213.v2.p2)
THIAZ_DIURETIC - Medication Indicator: Thiazide Diuretics (phv00173210.v2.p2)
TZD - Medication Indicator: Thiazolidinediones (phv00173216.v2.p2)
VASODIL - Medication Indicator: Vasodilators (phv00173211.v2.p2)

Mental Health (2)

BECKS_SCORE - Beck's Depression Index (phv00173274.v2.p2)
MMSE_SCORE - Total score of Modified Mini Mental State Exam: Score (phv00173275.v2.p2)

Race and Ethnicity (6)

BLACK - Black Race (Y/N) (phv00173284.v2.p2)
HISPANIC - Hispanic (y/n) (phv00173281.v2.p2)
RACE_CAT_1 - Race (3 Levels) (phv00543729.v1.p2)
RACE_ETHNICITY - Race Ethnicity (3 Levels) (phv00543730.v1.p2)
RACE_ETHNICITY_CAT2 - Race Ethnicity (4 Levels) (phv00173282.v2.p2)
WHITE - White Race (Y/N) (phv00173283.v2.p2)

Socioeconomic (3)

EDU_CAT_1 - Education Category (7-level) (phv00173286.v2.p2)
INCOME_CAT_1 - Household Income Category (4-level) (phv00173285.v2.p2)
MARSTAT2 - Marital Status Category (3-level) (phv00173287.v2.p2)

Study Administration (1)

FASTING - Fasting before blood draw(y/n) (phv00173241.v2.p2)

Substance Use (3)

ALCOH_USE - Alcohol Use (MedHX) (phv00173251.v2.p2)
SMOKE100 - Smoked 100 Cigarettes (phv00173243.v2.p2)
SMOKENOW - Current Smoker (phv00173244.v2.p2)

Other (31)

ANALYTE_TYPE - Analyte Type (phv00173293.v2.p2)
ANTI_ACIDOSIS - Medication Indicator: Anti-Acidosis (phv00173226.v2.p2)
BODY_SITE - Body site where sample was collected (phv00173292.v2.p2)
CCID - CCID (phv00173279.v2.p2)
CCIDSITE - CRIC Clinical Center-Site (phv00543728.v1.p2)
CONSENT - Consent group as determined by DAC (phv00173169.v2.p2)
DAYS_THISVISIT - Days from baseline visit to this visit date (phv00543742.v1.p2)
ERYTHROSTIM - Medication Indicator: Erythropoiesis stimulating (phv00173239.v2.p2)
FAMILYRD - Family History of Renal Disease (Yes/Not Yes) (phv00173290.v2.p2)
HISTOLOGICAL_TYPE - Cell or tissue type or subtype of sample (phv00173295.v2.p2)
HVY_MET - Activities with MET scores >=6 (phv00543750.v1.p2)
IS_TUMOR - Tumor status (phv00173294.v2.p2)
LIGHT_MET - Activities with MET scores of < 3 (phv00543748.v1.p2)
MAGNESIUM - Magnesium (mg/dL) (phv00173185.v2.p2)
MOD_MET - Activities with MET scores of 3 - < 6 (phv00543749.v1.p2)
MODHVY_MET - Activities with Met scores >=3 (phv00543751.v1.p2)
SA_ALLC_ESRD - SurvAn ESRD (phv00543762.v1.p2)
SA_ALLC_TIME_ESRD - SurvAn Time to dial/txp (years) (phv00543763.v1.p2)
SA_CVDCOMP3 - CHF(def/prob), MI(def/prob/poss), Stroke(def/prob) Composite Status (phv00543760.v1.p2)
SAMPLE_ID - Sample ID (phv00173291.v2.p2)
SAMPLE_ID - Sample ID (phv00173171.v2.p2)
STROKE - Stroke (Yes/Not Yes) (phv00173248.v2.p2)
SUBJECT_ID - Subject ID (phv00173172.v2.p2)
SUBJECT_ID - Subject ID (phv00173168.v2.p2)
SUBJECT_ID - Subject ID (phv00173170.v2.p2)
TIME_CHF_D - Time to CHF Definite (yrs) (phv00543757.v1.p2)
TIME_CVDCOMP3 - Time to CHF(def/prob), MI(def/prob/poss), Stroke(def/prob) Composite (yrs) (phv00543761.v1.p2)
TIME_DEATH - Time to death (yrs) (phv00543759.v1.p2)
TOTAL_MED - Total number of different medications (phv00543740.v1.p2)
VLDL - Very low-density Lipoprotein (mg/dL) (phv00173177.v2.p2)
VNUM - Visit number, 3=year 0(baseline),5=year 1 (phv00543727.v1.p2)