Burkitt lymphoma (BL) is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. We sequenced exomes of 59 BL tumors, 14 of which had paired normal tissue. Our work elucidates commonly occurring gene-coding mutations in Burkitt lymphoma and implicates ID3 as a novel tumor suppressor gene.

The Genetic Landscape of Mutations in Burkitt Lymphoma

Burkitt Lymphoma study with WXS data on dbGaP (59 participants)

The Genetic Landscape of Mutations in Burkitt Lymphoma

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