PGRN Antidepressant Medication Pharmacogenomic Study (AMPS)
Ancestry (4)
- EVEC.1 - 1st eigenvector from principal components analysis used as a covariate in adjusted GWAS (phv00196846.v1.p1)
- EVEC.2 - 2nd eigenvector from principal components analysis used as a covariate in adjusted GWAS (phv00196847.v1.p1)
- EVEC.3 - 3rd eigenvector from principal components analysis used as a covariate in adjusted GWAS (phv00196848.v1.p1)
- EVEC.4 - 4th eigenvector from principal components analysis used as a covariate in adjusted GWAS (phv00196849.v1.p1)
Anthropometry (2)
- height - Baseline Height (phv00195998.v1.p1)
- weight - Baseline Weight (phv00195999.v1.p1)
Demographics (3)
- age - Age at Consent (phv00195983.v1.p1)
- ageonset - Age at onset of first major depressive episode (phv00196006.v1.p1)
- gender - Gender (phv00195982.v1.p1)
Medications (4)
- dose.b - Dose of med.b drug prescribed at Baseline (phv00195995.v1.p1)
- dose.w4 - Dose of drug (citalopram/escitalopram) subject is taking on their Week 4 visit (phv00195996.v1.p1)
- dose.w8 - Dose of drug (citalopram/escitalopram) subject is taking on their Week 8 visit (phv00195997.v1.p1)
- med.b - Medication at Baseline (citalopram/escitalopram) (phv00195994.v1.p1)
Mental Health (8)
- hrsdtotal.b - HRSD (Hamilton Rating Scale for Depression) total score at Baseline (phv00195985.v1.p1)
- psychotherapy - Are you currently involved in psychotherapy (phv00196008.v1.p1)
- qidscpctchange - Difference between final visit QIDSC and baseline QIDSC, divided by baseline QIDSC and multiplied by 100. If no W4 or W8 data then change set to 0. (phv00196011.v1.p1)
- qidscpctchange.w4 - (([QIDSCTotal_W4]-[QIDSCTotal_B])/[QIDSCTotal_B]*100) (phv00195988.v1.p1)
- qidscpctchange.w8 - (([QIDSCTotal_W8]-[QIDSCTotal_B])/[QIDSCTotal_B]*100) (phv00195992.v1.p1)
- qidsctotal.b - QIDSC (Quick Inventory of Depressive Symptomatology) total score at Baseline (phv00195984.v1.p1)
- qidsctotal.w4 - QIDSC total score at Week 4 (phv00195986.v1.p1)
- qidsctotal.w8 - QIDSC total score at Week8 (phv00195990.v1.p1)
Race and Ethnicity (2)
- lookup.race - Race description (phv00195980.v1.p1)
- race - Race code (phv00195981.v1.p1)
Socioeconomic (4)
- currentempstat - Current employment status (phv00196005.v1.p1)
- highdegree - Highest degree completed (phv00196003.v1.p1)
- maritalstatus - Marital status (phv00196000.v1.p1)
- yearsschool - Total number of years completed (phv00196002.v1.p1)
Other (25)
- ANALYTE_TYPE - Analyte Type (phv00196020.v1.p1)
- BODY_SITE - Body site where sample was collected (phv00196019.v1.p1)
- CONSENT - Consent group as determined by DAC (phv00195975.v1.p1)
- consentMonth - Month subject consented to study (phv00196014.v1.p1)
- consentYear - Year subject consented to study (phv00196015.v1.p1)
- currentonsetMonth - Month of onset for current major depression episode (phv00196016.v1.p1)
- currentonsetYear - Year of onset for current major depression episode (phv00196017.v1.p1)
- currentstudent - Is subject currently in school (phv00196004.v1.p1)
- ExclusionReason - Non-Caucasian = Subject deemed non caucasian based on self-reported race and Structure Analyses Non-Compliant = Subject was deemed non compliant (phv00196013.v1.p1)
- IS_TUMOR - Tumor status (phv00196021.v1.p1)
- IsExcluded - Indicator of whether subject was excluded from GWAS (phv00196012.v1.p1)
- livewithspouse - Indicator of whether subject lives with spouse (phv00196001.v1.p1)
- qids.response2.w4 - Responder if QIDSCpctChange_W4 > = 50 , Non Responder if QIDSCpctChange_W4 < 50 (phv00195989.v1.p1)
- qids.response2.w8 - Responder if QIDSCpctChange_W8 >= 50 , Non Responder if QIDSCpctChange_W8 < 50 (phv00195993.v1.p1)
- remission - Last visit remission defined as Remitter if last visit QIDS C <= 5, Non Remitter if last visit QIDSC > 5. If no W4 or W8 data then remission defined as Non Remitter. (phv00196009.v1.p1)
- remissionqids.w4 - QIDSC remission status at Week 4 (Remitter if QIDSCTotal_W4 < =5, Non Remitter if QIDSCTotal_W4 > 5) (phv00195987.v1.p1)
- remissionqids.w8 - QIDSC remission status at Week 8 (Remitter if QIDSCTotal_W8 < =5, Non Remitter if QIDSCTotal_W8 > 5) (phv00195991.v1.p1)
- response - Last-visit response defined as Responder if QIDSCpctChange >=50 , Non Responder if QIDSCpctChange < 50. If no W4 or W8 data then response defined as Non Responder (phv00196010.v1.p1)
- SAMPLE_ID - De-identified Sample ID (SAME values as SUBJID) (phv00196018.v1.p1)
- SAMPLE_ID - Sample ID (SAME values as SUBJID) (phv00195977.v1.p1)
- SAMPLE_USE - Sample Use (phv00195978.v1.p1)
- seasonalpattern - Is there a seasonal pattern to your depression (phv00196007.v1.p1)
- SUBJID - De-identified Subject ID (phv00195979.v1.p1)
- SUBJID - Subject ID (phv00195976.v1.p1)
- SUBJID - Subject ID (phv00195974.v1.p1)