<p>RNA-seq data from two cases of ameloblastoma was analyzed for candidate gene fusions and point mutations. Recurrent point mutations identified in the RNA-seq data, as well as mutations identified with limited panel targeted deep sequencing, were validated as somatic. Expanding to a larger cohort of 28, one of two activating mutations was found in 80% of cases. No recurrent gene fusions events were identified.</p>

Identification of Recurrent SMO and BRAF Mutations in Ameloblastomas

Ameloblastoma study with AMPLICON, RNA Seq (NGS) data on dbGaP (7 participants)

Identification of Recurrent SMO and BRAF Mutations in Ameloblastomas

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