Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes
N. Saccone, S. Saccone, A. Hinrichs, et al.. (2009). American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Cited 238 times. https://doi.org/10.1002/ajmg.b.30828
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
The gene, environment association studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with ‘pleasurable buzz’ during early experimentation with smoking
Race differences in nicotine dependence in the Collaborative Genetic study of Nicotine Dependence (COGEND).
Zhehui Luo, G. F. Alvarado, D. Hatsukami, et al.. (2008). Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. Cited 59 times. https://doi.org/10.1080/14622200802163266
Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study.
Analysis of [3',3'-d(2)]-nicotine and [3',3'-d(2)]-cotinine by capillary liquid chromatography-electrospray tandem mass spectrometry.
S. Murphy, P. Villalta, S. Ho, et al.. (2007). Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. Cited 48 times. https://doi.org/10.1016/J.JCHROMB.2007.06.018
Association of CHRN genes with “dizziness” to tobacco
M. Ehringer, M. McQueen, Nicole R. Hoft, et al.. (2010). American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Cited 46 times. https://doi.org/10.1002/ajmg.b.31027
GENETIC STUDY: FULL ARTICLE: Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes
Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence.
Variants Weakly Correlated with CHRNA5 D398N Polymorphism Should be Considered in Transcriptional Deregulation at the 15q25 Locus Associated with Lung Cancer Risk