<p>We experimentally determined Mb-scale haplotypes from germline and cancer genome sequencing. Using a microfluidic process that partitions long DNA fragments into hundreds of thousands of barcoded reactions, we determined haplotype blocks from matched colorectal cancer samples in the delineation of haplotypes of allelic imbalances and other genomic instability events.</p>

Megabase-scale Haplotyped Genomic Analysis of Normal and Cancer Genomes

Colorectal Neoplasms study with WGS data on dbGaP (1 participants)

Megabase-scale Haplotyped Genomic Analysis of Normal and Cancer Genomes

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