<p>In this study, we separately performed PCR-free whole genome sequencing on the paired tumor/normal melanoma COLO-829 and lymphoblastoid COLO-829BL cell lines across three separate institutions (TGen, Illumina, Genome Sciences Centre at the British Columbia Cancer Agency). We performed a meta-analysis of all data, in combination with the originally reported analysis of these cell lines by <a href="http://www.ncbi.nlm.nih.gov/pubmed/20016485">Pleasance et al.</a>, and report a somatic reference standard based on consensus events. This standard can be used as a reference for tumor/normal whole genome analyses.</p>

Somatic Reference Standard for Cancer Sequencing

2 selected publications including "A comprehensive catalogue of somatic mutations from a human cancer gen..." (1,698 citations)

Somatic Reference Standard for Cancer Sequencing

A comprehensive catalogue of somatic mutations from a human cancer genome

A somatic reference standard for cancer genome sequencing