<p>In this study, six plasmacytoid bladder cancers were analyzed by whole exome sequencing. The results show loss of the CDH1 gene in every sample and correlate with E-cadherin loss of expression by immunohistochemistry. A separate validation cohort of plasmacytoid samples showed loss of E-cadherin expression by CDH1 mutation or promoter hypermethylation.</p>

Whole Exome Sequencing of Signet Ring/Plasmacytoid Variant Bladder Cancer

Carcinoma, Signet Ring Cell study with SNV Aggregate (.MAF), WXS data on dbGaP (6 participants)

Whole Exome Sequencing of Signet Ring/Plasmacytoid Variant Bladder Cancer

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