GeneSTAR NextGen Functional Genomics of Platelet Aggregation

Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs.

Cory J. Smith, A. Gore, Wei Yan, et al.. (2014). Cell stem cell. Cited 365 times. https://doi.org/10.1016/j.stem.2014.06.011

Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression.

Linzhao Cheng, Nancy F. Hansen, Ling Zhao, et al.. (2012). Cell stem cell. Cited 252 times. https://doi.org/10.1016/j.stem.2012.01.005

Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix

S. Kusuma, Yu‐I Shen, Donny Hanjaya‐Putra, et al.. (2013). Proceedings of the National Academy of Sciences. Cited 206 times. https://doi.org/10.1073/pnas.1306562110

Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression

Sarah N. Dowey, Xiaosong Huang, Bin-Kuan Chou, et al.. (2012). Nature Protocols. Cited 167 times. https://doi.org/10.1038/nprot.2012.121

Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions.

Ying Wang, Bin-Kuan Chou, Sarah N. Dowey, et al.. (2013). Stem cell research. Cited 134 times. https://doi.org/10.1016/j.scr.2013.07.011

A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans

R. Qayyum, B. Snively, E. Ziv, et al.. (2012). PLoS Genetics. Cited 106 times. https://doi.org/10.1371/journal.pgen.1002491

Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.

N. Faraday, L. Yanek, X. P. Yang, et al.. (2011). Blood. Cited 105 times. https://doi.org/10.1182/blood-2010-11-320788

Cathepsin G-Dependent Modulation of Platelet Thrombus Formation In Vivo by Blood Neutrophils

N. Faraday, Kathryn J. Schunke, Sofiyan Saleem, et al.. (2013). PLoS ONE. Cited 79 times. https://doi.org/10.1371/journal.pone.0071447

Efficient Generation of Megakaryocytes From Human Induced Pluripotent Stem Cells Using Food and Drug Administration‐Approved Pharmacological Reagents

Yanfeng Liu, Ying Wang, Yongxing Gao, et al.. (2015). STEM CELLS Translational Medicine. Cited 66 times. https://doi.org/10.5966/sctm.2014-0183

Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors.

Xiaosong Huang, Siddhartha K Shah, Jing Wang, et al.. (2014). Molecular therapy : the journal of the American Society of Gene Therapy. Cited 53 times. https://doi.org/10.1038/mt.2013.201

Concise Review: Stem Cell‐Based Approaches to Red Blood Cell Production for Transfusion

Siddhartha K Shah, Xiaosong Huang, Linzhao Cheng. (2014). STEM CELLS Translational Medicine. Cited 50 times. https://doi.org/10.5966/sctm.2013-0054

Bcl-xL enhances single-cell survival and expansion of human embryonic stem cells without affecting self-renewal.

H. Bai, Kang Chen, Yongxing Gao, et al.. (2012). Stem cell research. Cited 48 times. https://doi.org/10.1016/j.scr.2011.08.002

Concise Review: Human Cell Engineering: Cellular Reprogramming and Genome Editing

P. Mali, Linzhao Cheng. (2012). STEM CELLS. Cited 47 times. https://doi.org/10.1002/stem.735

Efficient and Scalable Expansion of Human Pluripotent Stem Cells Under Clinically Compliant Settings: A View in 2013

Y. Wang, Linzhao Cheng, S. Gerecht. (2013). Annals of Biomedical Engineering. Cited 45 times. https://doi.org/10.1007/s10439-013-0921-4

Differential Sensitivity to JAK Inhibitory Drugs by Isogenic Human Erythroblasts and Hematopoietic Progenitors Generated from Patient‐Specific Induced Pluripotent Stem Cells

Zhaohui Ye, Cyndi F. Liu, L. Lanikova, et al.. (2014). STEM CELLS. Cited 41 times. https://doi.org/10.1002/stem.1545

A Panel of CpG Methylation Sites Distinguishes Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

Kevin Huang, Yin Shen, Zhigang Xue, et al.. (2013). Stem Cell Reports. Cited 41 times. https://doi.org/10.1016/j.stemcr.2013.11.003

The Balance of Positive and Negative Effects of TGF-β Signaling Regulates the Development of Hematopoietic and Endothelial Progenitors in Human Pluripotent Stem Cells

H. Bai, Yin-liang Xie, Yongxing Gao, et al.. (2013). Stem Cells and Development. Cited 38 times. https://doi.org/10.1089/scd.2013.0008

Targeted Deep Resequencing Identifies Coding Variants in the PEAR1 Gene That Play a Role in Platelet Aggregation

Yoonhee Kim, B. Suktitipat, L. Yanek, et al.. (2013). PLoS ONE. Cited 31 times. https://doi.org/10.1371/journal.pone.0064179

Efficient Derivation and Genetic Modifications of Human Pluripotent Stem Cells on Engineered Human Feeder Cell Lines

C. Zou, Bin-Kuan Chou, Sarah N. Dowey, et al.. (2012). Stem Cells and Development. Cited 31 times. https://doi.org/10.1089/scd.2011.0688

Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing

Wei Yan, Cory J. Smith, Linzhao Cheng. (2013). Scientific Reports. Cited 26 times. https://doi.org/10.1038/srep02376

And then there were none: no need for pluripotency factors to induce reprogramming.

Bin-Kuan Chou, Linzhao Cheng. (2013). Cell stem cell. Cited 13 times. https://doi.org/10.1016/j.stem.2013.08.004

The Robustness of Generalized Estimating Equations for Association Tests in Extended Family Data

B. Suktitipat, R. Mathias, Dhananjay Vaidya, et al.. (2012). Human Heredity. Cited 10 times. https://doi.org/10.1159/000341636

Zinc fingers hit off target

Linzhao Cheng, B. Blazar, K. High, et al.. (2011). Nature Medicine. Cited 10 times. https://doi.org/10.1038/nm1011-1192

Generation and homing of iPSC-derived hematopoietic cells in vivo.

Bin-Kuan Chou, Zhaohui Ye, Linzhao Cheng. (2013). Molecular therapy : the journal of the American Society of Gene Therapy. Cited 7 times. https://doi.org/10.1038/mt.2013.129

On the threshold from genome-wide association studies to whole-genome sequencing. Looking for signal in all the right places.

N. Hansel, R. Mathias. (2014). American journal of respiratory and critical care medicine. https://doi.org/10.1164/rccm.201401-0048ED

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms.

Dhananjay Vaidya, L. Yanek, R. Mathias, et al.. (2014). British journal of medicine and medical research. https://doi.org/10.9734/BJMMR/2014/6117