Genes-Environments and Admixture in Latino Asthmatics (GALA II) Study

An integrated map of genetic variation from 1,092 human genomes

Gil A. David M. Richard M. Gonçalo R. David R. Aravind McVean Altshuler (Co-Chair) Durbin (Co-Chair) Abec, Gil A. McVean, David M. Richard M. Gonçalo R. David R. Aravinda Andrew Altshuler (Co-Chair) Durbin (Co-Chair) Abecasis Be, et al.. (2012). Nature. Cited 7,953 times. https://doi.org/10.1038/nature11632

Meta-analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations

D. Torgerson, E. Ampleford, Grace Y. Chiu, et al.. (2011). Nature genetics. Cited 821 times. https://doi.org/10.1038/ng.888

The genetics of Mexico recapitulates Native American substructure and affects biomedical traits

A. Moreno-Estrada, Christopher R. Gignoux, J. Fernández-López, et al.. (2014). Science. Cited 481 times. https://doi.org/10.1126/science.1251688

Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies.

Katherine K. Nishimura, J. Galanter, Lindsey A Roth, et al.. (2013). American journal of respiratory and critical care medicine. Cited 261 times. https://doi.org/10.1164/rccm.201302-0264OC

Genetic ancestry in lung-function predictions.

R. Kumar, M. Seibold, M. Aldrich, et al.. (2010). The New England journal of medicine. Cited 235 times. https://doi.org/10.1056/NEJMoa0907897

Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease.

Alex S. Poole, Cydney Urbanek, C. Eng, et al.. (2014). The Journal of allergy and clinical immunology. Cited 226 times. https://doi.org/10.1016/j.jaci.2013.11.025

Reconstructing Native American Migrations from Whole-Genome and Whole-Exome Data

S. Gravel, Fouad Zakharia, A. Moreno-Estrada, et al.. (2013). PLoS Genetics. Cited 178 times. https://doi.org/10.1371/journal.pgen.1004023

Childhood obesity and asthma control in the GALA II and SAGE II studies.

L. Borrell, Elizabeth A. Nguyen, Lindsey A Roth, et al.. (2013). American journal of respiratory and critical care medicine. Cited 132 times. https://doi.org/10.1164/rccm.201211-2116OC

Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies.

N. Thakur, Sam S. Oh, Elizabeth A. Nguyen, et al.. (2013). American journal of respiratory and critical care medicine. Cited 121 times. https://doi.org/10.1164/rccm.201306-1016OC

Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

J. Galanter, Christopher R. Gignoux, D. Torgerson, et al.. (2014). The Journal of allergy and clinical immunology. Cited 116 times. https://doi.org/10.1016/j.jaci.2013.08.055

Genetic ancestry influences asthma susceptibility and lung function among Latinos.

M. Pino-Yanes, M. Pino-Yanes, N. Thakur, et al.. (2015). The Journal of allergy and clinical immunology. Cited 113 times. https://doi.org/10.1016/j.jaci.2014.07.053

History Shaped the Geographic Distribution of Genomic Admixture on the Island of Puerto Rico

M. Via, Christopher R. Gignoux, Lindsey A Roth, et al.. (2011). PLoS ONE. Cited 109 times. https://doi.org/10.1371/journal.pone.0016513

A genome-wide association study of bronchodilator response in Latinos implicates rare variants.

Katherine A. Drake, D. Torgerson, Christopher R. Gignoux, et al.. (2014). The Journal of allergy and clinical immunology. Cited 109 times. https://doi.org/10.1016/j.jaci.2013.06.043

Ancestry-related assortative mating in Latino populations

N. Risch, S. Choudhry, M. Via, et al.. (2009). Genome Biology. Cited 92 times. https://doi.org/10.1186/gb-2009-10-11-r132

Effect of secondhand smoke on asthma control among black and Latino children.

Sam S. Oh, H. Tcheurekdjian, Lindsey A Roth, et al.. (2012). The Journal of allergy and clinical immunology. Cited 75 times. https://doi.org/10.1016/j.jaci.2012.03.017

Genome-wide interaction studies reveal sex-specific asthma risk alleles.

R. Myers, Nicole M. Scott, W. Gauderman, et al.. (2014). Human molecular genetics. Cited 71 times. https://doi.org/10.1093/hmg/ddu222

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

S. Bunyavanich, E. Schadt, B. Himes, et al.. (2014). BMC Medical Genomics. Cited 67 times. https://doi.org/10.1186/1755-8794-7-48

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.

PhD Albert M. Levin, ScD Rasika A. Mathias, Mph Lili Huang, et al.. (2013). The Journal of allergy and clinical immunology. Cited 58 times. https://doi.org/10.1016/j.jaci.2012.10.002

Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.

D. Torgerson, Christopher R. Gignoux, J. Galanter, et al.. (2012). The Journal of allergy and clinical immunology. Cited 55 times. https://doi.org/10.1016/j.jaci.2012.02.040

Socioeconomic status and asthma control in African American youth in SAGE II

N. Thakur, Melissa Martin, Elizabeth Castellanos, et al.. (2014). Journal of Asthma. Cited 48 times. https://doi.org/10.3109/02770903.2014.905593

Whole-Genome Sequencing of Individuals from a Founder Population Identifies Candidate Genes for Asthma

Catarina D. Campbell, Kiana Mohajeri, Maika Malig, et al.. (2014). PLoS ONE. Cited 41 times. https://doi.org/10.1371/journal.pone.0104396

Effects of positive end-expiratory pressure on anesthesia-induced atelectasis and gas exchange in anesthetized and mechanically ventilated sheep.

F. Staffieri, B. Driessen, V. D. Monte, et al.. (2010). American journal of veterinary research. Cited 40 times. https://doi.org/10.2460/ajvr.71.8.867

Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.

J. Galanter, D. Torgerson, Christopher R. Gignoux, et al.. (2011). The Journal of allergy and clinical immunology. Cited 35 times. https://doi.org/10.1016/j.jaci.2011.03.050

The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos

Marc Via, A. D. Giacomo, H. Corvol, et al.. (2010). Clinical & Experimental Allergy. Cited 34 times. https://doi.org/10.1111/j.1365-2222.2009.03438.x

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

R. Myers, B. Himes, Christopher R. Gignoux, et al.. (2012). The Journal of allergy and clinical immunology. Cited 32 times. https://doi.org/10.1016/j.jaci.2012.07.054

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

Blanca E. Himes, Blanca E. Himes, Keith S. Sheppard, et al.. (2013). PLoS ONE. Cited 32 times. https://doi.org/10.1371/journal.pone.0056179

Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: the Genes-environments and Admixture in Latino Asthmatics (GALA II) study.

R. Kumar, Elizabeth A. Nguyen, Lindsey A Roth, et al.. (2013). The Journal of allergy and clinical immunology. Cited 31 times. https://doi.org/10.1016/j.jaci.2013.02.046

Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.

D. Torgerson, D. Torgerson, D. Capurso, et al.. (2012). The Journal of allergy and clinical immunology. Cited 29 times. https://doi.org/10.1016/j.jaci.2012.03.045

The lung corps' approach to reducing health disparities in respiratory disease.

N. Thakur, M. McGarry, Sam S. Oh, et al.. (2014). Annals of the American Thoracic Society. Cited 19 times. https://doi.org/10.1513/AnnalsATS.201402-061AR