<p>Genetic factors play an important role in susceptibility to head and neck cancer and could also explain differences in response to treatment and outcome. The goal of this project is to investigate genetic variation involved in oral and oropharyngeal cancer susceptibility by performing the largest GWAS on these diseases, using a novel genotyping tool specifically designed for cancer studies by the OncoArray Network. This project encompasses data from approximately 6000 oral and pharynx cancer cases and 4000 controls derived from 12 epidemiological studies most of case-control design. The genotyping was centralized at the <a href="https://cidr.jhmi.edu/">Center for Inherited Disease Research</a> (CIDR), and the epidemiological data harmonization and analysis were completed at the <a href="https://www.iarc.who.int/">International Agency for Research on Cancer</a> (IARC). This study was supported by <a href="https://www.nidcr.nih.gov/">National Institute of Dental and Craniofacial Research</a> (NIDCR) with direct funding to CIDR.</p>

OncoArray: Oral and Pharynx Cancer

Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer