<p>Paired DNA and RNA profiling is increasingly employed in genomics research to uncover molecular mechanisms of disease and to explore personal genotype and phenotype correlations. We developed a novel simultaneous DNA and RNA sequencing approach (Simul-seq) that enables comprehensive genomic and transcriptomic profiles from small quantities of cells or tissues. In this study, Simul-seq was performed on patient-derived fibroblast cells as well as an esophageal adenocarcinoma tumor sample and compared with standard DNA and RNA-sequencing approaches.</p>

DNA and RNA Profiling Using Simultaneous Sequencing (Simul-seq)

Esophageal Neoplasms study with RNA-Seq, WGA + 1 more data on dbGaP (2 participants)

DNA and RNA Profiling Using Simultaneous Sequencing (Simul-seq)

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