<p>Paired DNA and RNA profiling is increasingly employed in genomics research to uncover molecular mechanisms of disease and to explore personal genotype and phenotype correlations. We developed a novel simultaneous DNA and RNA sequencing approach (Simul-seq) that enables comprehensive genomic and transcriptomic profiles from small quantities of cells or tissues. In this study, Simul-seq was performed on patient-derived fibroblast cells as well as an esophageal adenocarcinoma tumor sample and compared with standard DNA and RNA-sequencing approaches.</p>

DNA and RNA Profiling Using Simultaneous Sequencing (Simul-seq)

1 selected publication including "Simul-seq: combined DNA and RNA sequencing for whole-genome and transc..." (41 citations)

DNA and RNA Profiling Using Simultaneous Sequencing (Simul-seq)

Simul-seq: combined DNA and RNA sequencing for whole-genome and transcriptome profiling