<p>Genetic risk factors for ulcerative colitis are not well understood. We performed a family-based whole exome sequencing analysis to identify potential causal mutations. In the proband, we found a heterozygous de novo mutation in the gene HSPA1L. Our results indicate that the de novo mutation in HSPA1L is associated with ulcerative colitis.</p>

Family-Based Study on Ulcerative Colitis with Whole Exome Sequencing

Colitis, Ulcerative study with WGS, WXS data on dbGaP (4 participants)

Family-Based Study on Ulcerative Colitis with Whole Exome Sequencing

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