Pharmacogenetics of Efavirenz Discontinuation for Reported CNS Symptoms
Ancestry (6)
- C1 - MDS coordinates generated from GWAS genotype - C1 (phv00282546.v1.p1)
- C2 - MDS coordinates generated from GWAS genotype - C2 (phv00282547.v1.p1)
- C3 - MDS coordinates generated from GWAS genotype - C3 (phv00282548.v1.p1)
- C4 - MDS coordinates generated from GWAS genotype - C4 (phv00282549.v1.p1)
- racegeno - Genetic ancestry defined race from MDS plots (phv00282529.v1.p1)
- racegeno - Genetic ancestry defined from MDS plots. (phv00282539.v1.p1)
Demographics (3)
- age_at_art_start - Age of participant at ART initiation (phv00282535.v1.p1)
- age_last_visit - Age of participant at the last clinic visit (phv00282533.v1.p1)
- sex - Gender of participant (phv00282531.v1.p1)
Other (25)
- AFFECTION_STATUS - Case - control status of the subject (phv00282522.v1.p1)
- ANALYTE_TYPE - Analyte Type (phv00282551.v1.p1)
- CONSENT - Consent group as determined by DAC (phv00282519.v1.p1)
- dc_cause_final - Validation Causes of EFV Discontinuation (phv00282528.v1.p1)
- efv_dc_cns_symptoms - Discontinuation of EFV for CNS side effects (phv00282527.v1.p1)
- efv_perm_dc - Permanent discontinuation of EFV (phv00282532.v1.p1)
- fup_art_total_day - Total days of ART treatment (phv00282537.v1.p1)
- fup_efv_total_day - Total days of EFV treatment (phv00282530.v1.p1)
- haplotype - Defined haplotypes based on combination of CYPAB6 and CYP2A6 SNPs. (phv00282544.v1.p1)
- metabolizer - Metabolizer status based on haplotypes (phv00282545.v1.p1)
- regimen_nbr - Number of different ART regimens (phv00282536.v1.p1)
- rs28399433 - SNP in CYP2A6 - rs28399433 (phv00282543.v1.p1)
- rs28399499 - SNP in CYP2B6 - rs28399499 (phv00282542.v1.p1)
- rs3745274 - SNP in CYP2B6 - rs3745274 (phv00282541.v1.p1)
- rs4803419 - SNP in CYP2B6 - rs4803419 (phv00282540.v1.p1)
- SAMPLE_ID - Sample ID (phv00282524.v1.p1)
- SAMPLE_ID - De-identified Sample ID (phv00282550.v1.p1)
- SAMPLE_USE - Sample Use (phv00282525.v1.p1)
- SOURCE_SUBJID - Subject ID used in the Source Repository (phv00282521.v1.p1)
- SUBJ_SOURCE - Source repository where subjects originate (phv00282520.v1.p1)
- SUBJECT_ID - De-identified Subject ID (phv00282526.v1.p1)
- SUBJECT_ID - De-identified Subject ID (phv00282538.v1.p1)
- SUBJECT_ID - Subject ID (phv00282518.v1.p1)
- SUBJECT_ID - Subject ID (phv00282523.v1.p1)
- yr_last_visit - Year of the last clinic visit (phv00282534.v1.p1)