Resistance to Checkpoint Blockade Therapy Through Inactivation of Antigen Presentation

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The blockade of immune checkpoints in cancer immunotherapy

D. Pardoll. (2012). Nature Reviews Cancer. Cited 12,491 times. https://doi.org/10.1038/nrc3239

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma.

J. Zaretsky, A. García-Díaz, D. Shin, et al.. (2016). The New England journal of medicine. Cited 2,644 times. https://doi.org/10.1056/NEJMoa1604958

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

E. V. Van Allen, Diana Miao, B. Schilling, et al.. (2015). Science. Cited 2,521 times. https://doi.org/10.1126/science.aad0095

Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

Jeffrey S. Weber, S. D’Angelo, D. Minor, et al.. (2015). The Lancet. Oncology. Cited 2,502 times. https://doi.org/10.1016/S1470-2045(15)70076-8

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

Jianjun Gao, L. Shi, Hao Zhao, et al.. (2016). Cell. Cited 1,142 times. https://doi.org/10.1016/j.cell.2016.08.069

Implication of the β2-microglobulin gene in the generation of tumor escape phenotypes

M. Bernal, F. Ruiz-Cabello, A. Concha, et al.. (2012). Cancer Immunology, Immunotherapy. Cited 118 times. https://doi.org/10.1007/s00262-012-1321-6

Beta2‐microglobulin mutations in microsatellite unstable colorectal tumors

M. Kloor, S. Michel, Boris Buckowitz, et al.. (2007). International Journal of Cancer. Cited 114 times. https://doi.org/10.1002/ijc.22691
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