NHLBI TOPMed: Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)

Meta-analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations

D. Torgerson, E. Ampleford, Grace Y. Chiu, et al.. (2011). Nature genetics. Cited 821 times. https://doi.org/10.1038/ng.888

Multi-ethnic genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Lavinia Marie Johannes Hansjörg Melanie David P John A Kla Paternoster Standl Waage Baurecht Hotze Strachan C, L. Paternoster, M. Standl, et al.. (2015). Nature genetics. Cited 572 times. https://doi.org/10.1038/ng.3424

Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence.

L. Williams, E. Peterson, K. Wells, et al.. (2011). The Journal of allergy and clinical immunology. Cited 326 times. https://doi.org/10.1016/j.jaci.2011.09.011

A Meta-Analysis Identifies New Loci Associated with Body Mass index in Individuals of African Ancestry

K. Monda, K. Monda, Gary K. Chen, et al.. (2013). Nature genetics. Cited 255 times. https://doi.org/10.1038/ng.2608

Genetic ancestry in lung-function predictions.

R. Kumar, M. Seibold, M. Aldrich, et al.. (2010). The New England journal of medicine. Cited 235 times. https://doi.org/10.1056/NEJMoa0907897

Variation in the Glucose Transporter gene SLC2A2 is associated with glycaemic response to metformin

K. Zhou, S. Yee, E. Seiser, et al.. (2016). Nature genetics. Cited 193 times. https://doi.org/10.1038/ng.3632

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

R. Mathias, M. Taub, Christopher R. Gignoux, et al.. (2016). Nature Communications. Cited 152 times. https://doi.org/10.1038/ncomms12522

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium

M. Ng, M. Graff, Yingchang Lu, et al.. (2017). PLoS Genetics. Cited 124 times. https://doi.org/10.1371/journal.pgen.1006719

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

C. Igartua, R. Myers, R. Mathias, et al.. (2015). Nature Communications. Cited 75 times. https://doi.org/10.1038/ncomms6965

Genome-wide interaction studies reveal sex-specific asthma risk alleles.

R. Myers, Nicole M. Scott, W. Gauderman, et al.. (2014). Human molecular genetics. Cited 71 times. https://doi.org/10.1093/hmg/ddu222

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis

S. Bunyavanich, E. Schadt, B. Himes, et al.. (2014). BMC Medical Genomics. Cited 67 times. https://doi.org/10.1186/1755-8794-7-48

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.

PhD Albert M. Levin, ScD Rasika A. Mathias, Mph Lili Huang, et al.. (2013). The Journal of allergy and clinical immunology. Cited 58 times. https://doi.org/10.1016/j.jaci.2012.10.002

Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma.

J. Rumpel, B. Ahmedani, E. Peterson, et al.. (2012). The Journal of allergy and clinical immunology. Cited 55 times. https://doi.org/10.1016/j.jaci.2012.09.001

An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function

James J. Yang, Jia Li, L. K. Williams, et al.. (2016). BMC Bioinformatics. Cited 52 times. https://doi.org/10.1186/s12859-015-0868-6

The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population.

Karen E. Wells, Karen E. Wells, E. Peterson, et al.. (2012). The Journal of allergy and clinical immunology. Cited 45 times. https://doi.org/10.1016/j.jaci.2011.12.974

Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma.

Wendy Gould, E. Peterson, G. Karungi, et al.. (2010). The Journal of allergy and clinical immunology. Cited 40 times. https://doi.org/10.1016/j.jaci.2010.08.002

Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients.

Ying Jin, Ying Jin, D. Hu, et al.. (2010). The Journal of allergy and clinical immunology. Cited 38 times. https://doi.org/10.1016/j.jaci.2010.06.007

Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups

Badri K. Padhukasahasram, James J. Yang, A. Levin, et al.. (2014). The pharmacogenomics journal. Cited 38 times. https://doi.org/10.1038/tpj.2013.49

Nocturnal asthma and the importance of race/ethnicity and genetic ancestry.

A. Levin, Yun Wang, Karen E. Wells, et al.. (2014). American journal of respiratory and critical care medicine. Cited 33 times. https://doi.org/10.1164/rccm.201402-0204OC

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

R. Myers, B. Himes, Christopher R. Gignoux, et al.. (2012). The Journal of allergy and clinical immunology. Cited 32 times. https://doi.org/10.1016/j.jaci.2012.07.054

Assessing differences in inhaled corticosteroid response by self-reported race-ethnicity and genetic ancestry among asthmatic subjects.

K. Wells, S. Cajigal, Edward L. Peterson, et al.. (2016). The Journal of allergy and clinical immunology. Cited 28 times. https://doi.org/10.1016/j.jaci.2015.12.1334

Predictive Properties of the Asthma Control Test and Its Component Questions for Severe Asthma Exacerbations.

S. Cajigal, K. Wells, E. Peterson, et al.. (2017). The journal of allergy and clinical immunology. In practice. Cited 28 times. https://doi.org/10.1016/j.jaip.2016.06.025

Efficient inference of local ancestry

James J. Yang, Jia Li, A. Buu, et al.. (2013). Bioinformatics. Cited 23 times. https://doi.org/10.1093/bioinformatics/btt488

Identifying Pleiotropic Genes in Genome-Wide Association Studies for Multivariate Phenotypes with Mixed Measurement Scales

James J. Yang, Keoki L. Williams, Henry Ford. (2017). PLoS ONE. Cited 11 times. https://doi.org/10.1371/journal.pone.0169893

Genetic variation in B cell-activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects.

R. Kumar, L. Williams, A. Kato, et al.. (2012). The Journal of allergy and clinical immunology. Cited 10 times. https://doi.org/10.1016/j.jaci.2012.04.047

Powerful Tests for Multi-Marker Association Analysis Using Ensemble Learning

Badri K. Padhukasahasram, Chandan K. Reddy, A. Levin, et al.. (2014). PLoS ONE. Cited 1 times. https://doi.org/10.1101/005405

An efficient genome-wide association test for mixed binary and continuous phenotypes with applications to substance abuse research

A. Buu, L Keoki Williams, James J Yang. (2018). Statistical Methods in Medical Research. Cited 1 times. https://doi.org/10.1177/0962280216647422