<p>Small cell carcinoma of the ovary-hypercalcemic type (SCCOHT) is a rare and aggressive form of ovarian cancer afflicting young women at a median age of 24 years. SCCOHTs are characterized by loss of protein expression of SWI/SNF chromatin remodeling ATPases SMARCA4 and SMARCA2 through mutation and epigenetic silencing, respectively. This study aims to establish gene expression profiles of this cancer through RNA-Seq of fourteen pathologically confirmed cases of SCCOHT tumors.</p>

Gene Expression of Small Cell Carcinoma of the Ovary-Hypercalcemic Type    (SCCOHT)

1 selected publication including "Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of t..." (56 citations)

Gene Expression of Small Cell Carcinoma of the Ovary-Hypercalcemic Type (SCCOHT)

Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition