Intravenous Norepinephrine for Orthostatic Hypotension

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Biomarkers (20)

BPd_0 - Blood Pressure Diastolic - 0 degree (phv00397116.v1.p1)
BPd_20 - Blood Pressure Diastolic - 20 degree (phv00397130.v1.p1)
BPd_40 - Blood Pressure Diastolic - 40 degree (phv00397144.v1.p1)
BPd_60 - Blood Pressure Diastolic - 60 degree (phv00397159.v1.p1)
BPs_0 - Blood Pressure Systolic - 0 degree (phv00397115.v1.p1)
BPs_20 - Blood Pressure Systolic - 20 degree (phv00397129.v1.p1)
BPs_40 - Blood Pressure Systolic - 40 degree (phv00397143.v1.p1)
BPs_60 - Blood Pressure Systolic - 60 degree (phv00397158.v1.p1)
HR_0 - Heart Rate- 0 degree (phv00397118.v1.p1)
HR_20 - Heart Rate- 20 degree (phv00397132.v1.p1)
HR_40 - Heart Rate- 40 degree (phv00397146.v1.p1)
HR_60 - Heart Rate- 60 degree (phv00397161.v1.p1)
TPR_0_1 - Total Peripheral Resistance, measured with BioZ Cardio Profile-monitor - 0 degree (phv00397125.v1.p1)
TPR_0_2 - Total Peripheral Resistance, measured with Nexfin monitoring system - 0 degree (phv00397126.v1.p1)
TPR_20_1 - Total Peripheral Resistance, measured with BioZ Cardio Profile-monitor - 20 degree (phv00397139.v1.p1)
TPR_20_2 - Total Peripheral Resistance, measured with Nexfin monitoring system - 20 degree (phv00397140.v1.p1)
TPR_40_1 - Total Peripheral Resistance, measured with BioZ Cardio Profile-monitor - 40 degree (phv00397153.v1.p1)
TPR_40_2 - Total Peripheral Resistance, measured with Nexfin monitoring system - 40 degree (phv00397154.v1.p1)
TPR_60_1 - Total Peripheral Resistance, measured with BioZ Cardio Profile-monitor - 60 degree (phv00397167.v1.p1)
TPR_60_2 - Total Peripheral Resistance, measured with Nexfin monitoring system - 60 degree (phv00397168.v1.p1)

Demographics (3)

Age - Age (phv00397228.v1.p1)
Age_at_visit - Age at visit in days (phv00397109.v1.p1)
Sex - Gender (phv00397232.v1.p1)

Disease Events (1)

Orth_Hypotension - Orth. Hypostenion present (phv00397242.v1.p1)

Medications (13)

Other_Rxs_specify1 - Use of other prescriptions - specify 1 (phv00397264.v1.p1)
Other_Rxs_specify2 - Use of other prescriptions - specify 2 (phv00397265.v1.p1)
Other_Rxs1 - Use of Selegiline (phv00397254.v1.p1)
Other_Rxs10 - Use of Beta-blk. (phv00397263.v1.p1)
Other_Rxs2 - Use of Rasagiline (phv00397255.v1.p1)
Other_Rxs3 - Use of DA Agonist (phv00397256.v1.p1)
Other_Rxs4 - Use of Amantadine (phv00397257.v1.p1)
Other_Rxs5 - Use of COMTI (phv00397258.v1.p1)
Other_Rxs6 - Use of Florinef (phv00397259.v1.p1)
Other_Rxs7 - Use of Midodrine (phv00397260.v1.p1)
Other_Rxs8 - Use of SSRI (phv00397261.v1.p1)
Other_Rxs9 - Use of Aspirin (phv00397262.v1.p1)
Sinemet_LDOPA - Use of sinemet for treatment (phv00397253.v1.p1)

Mental Health (2)

Dementia - Dementia (phv00397251.v1.p1)
Depression - Depression present (phv00397250.v1.p1)

Race and Ethnicity (2)

Ethnicity - Ethnicity (phv00397231.v1.p1)
Race - Race (phv00397230.v1.p1)

Other (123)

Bradykin - Bradykinesia present (phv00397238.v1.p1)
CO_0_1 - Cardiac Output, measured with BioZ Cardio Profile-monitor - 0 degree (phv00397123.v1.p1)
CO_0_2 - Cardiac Output, measured with Nexfin monitoring system - 0 degree (phv00397124.v1.p1)
CO_20_1 - Cardiac Output, measured with BioZ Cardio Profile-monitor - 20 degree (phv00397137.v1.p1)
CO_20_2 - Cardiac Output, measured with Nexfin monitoring system - 20 degree (phv00397138.v1.p1)
CO_40_1 - Cardiac Output, measured with BioZ Cardio Profile-monitor - 40 degree (phv00397151.v1.p1)
CO_40_2 - Cardiac Output, measured with Nexfin monitoring system - 40 degree (phv00397152.v1.p1)
CO_60_1 - Cardiac Output, measured with BioZ Cardio Profile-monitor - 60 degree (phv00397165.v1.p1)
CO_60_2 - Cardiac Output, measured with Nexfin monitoring system - 60 degree (phv00397166.v1.p1)
Condition_0_Set1 - 0 Degree tilt - Hemodynamic Assessments (phv00397113.v1.p1)
Condition_0_Set2 - 0 Degree tilt - Blood Sampling (phv00397170.v1.p1)
Condition_20_Set1 - 20 Degree tilt - Hemodynamic Assessments (phv00397128.v1.p1)
Condition_20_Set2 - 20 Degree tilt - Blood Sampling (phv00397184.v1.p1)
Condition_40_Set1 - 40 Degree tilt - Hemodynamic Assessments (phv00397142.v1.p1)
Condition_40_Set2 - 40 Degree tilt - Blood Sampling (phv00397198.v1.p1)
Condition_60_Set1 - 60 Degree tilt - Hemodynamic Assessments (phv00397156.v1.p1)
Condition_60_Set2 - 60 Degree tilt - Blood Sampling (phv00397212.v1.p1)
consent - Consent Group (phv00397103.v1.p1)
Constipation - Constipation present (phv00397247.v1.p1)
DA_0_1 - Dopamine - 0 degree, measurement 1 (phv00397175.v1.p1)
DA_0_2 - Dopamine - 0 degree, measurement 2 (phv00397181.v1.p1)
DA_20_1 - Dopamine - 20 degree, measurement 1 (phv00397189.v1.p1)
DA_20_2 - Dopamine - 20 degree, measurement 2 (phv00397195.v1.p1)
DA_40_1 - Dopamine - 40 degree, measurement 1 (phv00397203.v1.p1)
DA_40_2 - Dopamine - 40 degree, measurement 2 (phv00397209.v1.p1)
DA_60_1 - Dopamine - 60 degree, measurement 1 (phv00397217.v1.p1)
DA_60_2 - Dopamine - 60 degree, measurement 2 (phv00397223.v1.p1)
de_Novo_PD - Newly diagnosed PD (phv00397236.v1.p1)
Decreased_sweat - Decreased sweat present (phv00397248.v1.p1)
Definite_or_not - Diagnosis confirmed (phv00397107.v1.p1)
Definite_or_not - Diagnosis confirmed (phv00397227.v1.p1)
DHPG_0_1 - Arterial Plasma Levels of Dihydroxyphenylglycol - 0 degree, measurement 1 (phv00397171.v1.p1)
DHPG_0_2 - Arterial Plasma Levels of Dihydroxyphenylglycol - 0 degree, measurement 2 (phv00397177.v1.p1)
DHPG_20_1 - Arterial Plasma Levels of Dihydroxyphenylglycol - 20 degree, measurement 1 (phv00397185.v1.p1)
DHPG_20_2 - Arterial Plasma Levels of Dihydroxyphenylglycol - 20 degree, measurement 2 (phv00397191.v1.p1)
DHPG_40_1 - Arterial Plasma Levels of Dihydroxyphenylglycol - 40 degree, measurement 1 (phv00397199.v1.p1)
DHPG_40_2 - Arterial Plasma Levels of Dihydroxyphenylglycol - 40 degree, measurement 2 (phv00397205.v1.p1)
DHPG_60_1 - Arterial Plasma Levels of Dihydroxyphenylglycol - 60 degree, measurement 1 (phv00397213.v1.p1)
DHPG_60_2 - Arterial Plasma Levels of Dihydroxyphenylglycol - 60 degree, measurement 2 (phv00397219.v1.p1)
Diagnosis - Diagnosis (phv00397106.v1.p1)
Diagnosis - Diagnosis (phv00397226.v1.p1)
DOPA_0_1 - L-DOPA- 0 degree, measurement 1 (phv00397173.v1.p1)
DOPA_0_2 - L-DOPA- 0 degree, measurement 2 (phv00397179.v1.p1)
DOPA_20_1 - L-DOPA- 20 degree, measurement 1 (phv00397187.v1.p1)
DOPA_20_2 - L-DOPA- 20 degree, measurement 2 (phv00397193.v1.p1)
DOPA_40_1 - L-DOPA- 40 degree, measurement 1 (phv00397201.v1.p1)
DOPA_40_2 - L-DOPA- 40 degree, measurement 2 (phv00397207.v1.p1)
DOPA_60_1 - L-DOPA- 60 degree, measurement 1 (phv00397215.v1.p1)
DOPA_60_2 - L-DOPA- 60 degree, measurement 2 (phv00397221.v1.p1)
DOPAC_0_1 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 0 degree, measurement 1 (phv00397176.v1.p1)
DOPAC_0_2 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 0 degree, measurement 2 (phv00397182.v1.p1)
DOPAC_20_1 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 20 degree, measurement 1 (phv00397190.v1.p1)
DOPAC_20_2 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 20 degree, measurement 2 (phv00397196.v1.p1)
DOPAC_40_1 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 40 degree, measurement 1 (phv00397204.v1.p1)
DOPAC_40_2 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 40 degree, measurement 2 (phv00397210.v1.p1)
DOPAC_60_1 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 60 degree, measurement 1 (phv00397218.v1.p1)
DOPAC_60_2 - 3,4-Dihydroxyphenylacetic acid (metabolite of the neurotransmitter dopamine) - 60 degree, measurement 2 (phv00397224.v1.p1)
Early_OH - Early onset of orthostatic hypotension (phv00397233.v1.p1)
EPI_0_1 - Epinephrine - 0 degree, measurement 1 (phv00397174.v1.p1)
EPI_0_2 - Epinephrine - 0 degree, measurement 2 (phv00397180.v1.p1)
EPI_20_1 - Epinephrine - 20 degree, measurement 1 (phv00397188.v1.p1)
EPI_20_2 - Epinephrine - 20 degree, measurement 2 (phv00397194.v1.p1)
EPI_40_1 - Epinephrine - 40 degree, measurement 1 (phv00397202.v1.p1)
EPI_40_2 - Epinephrine - 40 degree, measurement 2 (phv00397208.v1.p1)
EPI_60_1 - Epinephrine - 60 degree, measurement 1 (phv00397216.v1.p1)
EPI_60_2 - Epinephrine - 60 degree, measurement 2 (phv00397222.v1.p1)
Fatigue - Fatigue present (phv00397252.v1.p1)
FBF_0 - Forearm Blood Flow - 0 degree (phv00397119.v1.p1)
FBF_20 - Forearm Blood Flow- 20 degree (phv00397133.v1.p1)
FBF_40 - Forearm Blood Flow- 40 degree (phv00397147.v1.p1)
FBF_60 - Forearm Blood Flow- 60 degree (phv00397157.v1.p1)
FVR_0 - Forearm Vascular Resistance- 0 degree (phv00397120.v1.p1)
FVR_20 - Forearm Vascular Resistance- 20 degree (phv00397134.v1.p1)
FVR_40 - Forearm Vascular Resistance- 40 degree (phv00397148.v1.p1)
FVR_60 - Forearm Vascular Resistance- 60 degree (phv00397162.v1.p1)
ge_60 - Age greater than 60 (phv00397229.v1.p1)
Impotence - Impotence present (phv00397246.v1.p1)
Ldopa_responsive - Movement (phv00397241.v1.p1)
MAP_0 - Mean Arterial Pressure - 0 degree (phv00397117.v1.p1)
MAP_20 - Mean Arterial Pressure - 20 degree (phv00397131.v1.p1)
MAP_40 - Mean Arterial Pressure - 40 degree (phv00397145.v1.p1)
MAP_60 - Mean Arterial Pressure - 60 degree (phv00397160.v1.p1)
maskid - Masked Subject ID (phv00397104.v1.p1)
maskid - Masked Subject ID (phv00397225.v1.p1)
maskid - (Masked) Subject Identifier (unique key) (phv00397102.v1.p1)
Motor_Dysf_Age_at_Onset - Motor dysfunction age of onset (phv00397234.v1.p1)
NE_0_1 - Arterial Plasma Levels of Norepinephrine - 0 degree, measurement 1 (phv00397172.v1.p1)
NE_0_2 - Arterial Plasma Levels of Norepinephrine - 0 degree, measurement 2 (phv00397178.v1.p1)
NE_20_1 - Arterial Plasma Levels of Norepinephrine - 20 degree, measurement 1 (phv00397186.v1.p1)
NE_20_2 - Arterial Plasma Levels of Norepinephrine - 20 degree, measurement 2 (phv00397192.v1.p1)
NE_40_1 - Arterial Plasma Levels of Norepinephrine - 40 degree, measurement 1 (phv00397200.v1.p1)
NE_40_2 - Arterial Plasma Levels of Norepinephrine - 40 degree, measurement 2 (phv00397206.v1.p1)
NE_60_1 - Arterial Plasma Levels of Norepinephrine - 60 degree, measurement 1 (phv00397214.v1.p1)
NE_60_2 - Arterial Plasma Levels of Norepinephrine - 60 degree, measurement 2 (phv00397220.v1.p1)
NE_INF_Conc - NE Infusion Conc (phv00397111.v1.p1)
NE_INF_Rate - Rate of NE infusion (phv00397110.v1.p1)
On_Sinemet_or_not - On Sinemet treatment (phv00397108.v1.p1)
Orth_Intolerance - Orth. Intolerance present (phv00397243.v1.p1)
Plac_NE_First - Placebo or Norepinephrine administered first (phv00397114.v1.p1)
Resting - Tremor (phv00397239.v1.p1)
Rigidity - Cogwheel (phv00397240.v1.p1)
Slurred_Speech - Slurred Speech present (phv00397249.v1.p1)
SV_0_1 - Cardiac Stroke Volume, measured with BioZ Cardio Profile-monitor - 0 degree (phv00397121.v1.p1)
SV_0_2 - Cardiac Stroke Volume, measured with Nexfin monitoring system - 0 degree (phv00397122.v1.p1)
SV_20_1 - Cardiac Stroke Volume, measured with BioZ Cardio Profile-monitor - 20 degree (phv00397135.v1.p1)
SV_20_2 - Cardiac Stroke Volume, measured with Nexfin monitoring system - 20 degree (phv00397136.v1.p1)
SV_40_1 - Cardiac Stroke Volume, measured with BioZ Cardio Profile-monitor - 40 degree (phv00397149.v1.p1)
SV_40_2 - Cardiac Stroke Volume, measured with Nexfin monitoring system - 40 degree (phv00397150.v1.p1)
SV_60_1 - Cardiac Stroke Volume, measured with BioZ Cardio Profile-monitor - 60 degree (phv00397163.v1.p1)
SV_60_2 - Cardiac Stroke Volume, measured with Nexfin monitoring system - 60 degree (phv00397164.v1.p1)
TIME_0_Set1 - Start time of evaluation - 0 degree, Hemodynamic Assessments (phv00397112.v1.p1)
TIME_0_Set2 - Start time of evaluation - 0 degree, Blood Sampling (phv00397169.v1.p1)
TIME_20_Set1 - Start time of evaluation - 20 degree, Hemodynamic Assessments (phv00397127.v1.p1)
TIME_20_Set2 - Start time of evaluation - 20 degree, Blood Sampling (phv00397183.v1.p1)
TIME_40_Set1 - Start time of evaluation - 40 degree, Hemodynamic Assessments (phv00397141.v1.p1)
TIME_40_Set2 - Start time of evaluation - 40 degree, Blood Sampling (phv00397197.v1.p1)
TIME_60_Set1 - Start time of evaluation - 60 degree, Hemodynamic Assessments (phv00397155.v1.p1)
TIME_60_Set2 - Start time of evaluation - 60 degree, Blood Sampling (phv00397211.v1.p1)
Time_Onset_to_Study - Time of onset to study participation (phv00397235.v1.p1)
Treatment - Treatment group: baseline tilt, placebo or NE (phv00397105.v1.p1)
Type - Type of urinary symptoms (phv00397245.v1.p1)
Unilat_or_not - PD unilateral involvement (phv00397237.v1.p1)
Urinary_symptoms - Urinary symptoms present (phv00397244.v1.p1)