Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.
Donavan T. Cheng, Talia Mitchell, A. Zehir, et al.. (2015). The Journal of molecular diagnostics : JMD. Cited 1,871 times. https://doi.org/10.1016/j.jmoldx.2014.12.006Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations.
D. Hyman, I. Puzanov, V. Subbiah, et al.. (2015). The New England journal of medicine. Cited 1,589 times. https://doi.org/10.1056/NEJMoa1502309The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Jinghui Zhang, L. Ding, Linda Holmfeldt, et al.. (2012). Nature. Cited 1,570 times. https://doi.org/10.1038/nature10725Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.
Rikhia Chakraborty, O. Hampton, Xiaoyun Shen, et al.. (2014). Blood. Cited 388 times. https://doi.org/10.1182/blood-2014-05-577825High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden
R. Benayed, M. Offin, Kerry A Mullaney, et al.. (2019). Clinical Cancer Research. Cited 371 times. https://doi.org/10.1158/1078-0432.CCR-19-0225An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.
T. Gruber, Amanda Larson Gedman, Jinghui Zhang, et al.. (2012). Cancer cell. Cited 273 times. https://doi.org/10.1016/j.ccr.2012.10.007Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects.
Xu-ming Dai, Gregory R. Ryan, A. Hapel, et al.. (2002). Blood. Cited 271 times.A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
E. Mass, C. Jacome-Galarza, T. Blank, et al.. (2017). Nature. Cited 181 times. https://doi.org/10.1038/nature23672Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells.
B. Durham, Damien Roos-Weil, C. Baillou, et al.. (2017). Blood. Cited 118 times. https://doi.org/10.1182/blood-2016-12-757377Extracellular assembly and activation principles of oncogenic class III receptor tyrosine kinases
K. Verstraete, S. Savvides. (2012). Nature Reviews Cancer. Cited 86 times. https://doi.org/10.1038/nrc3371Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor.
J. Felix, J. Elegheert, I. Gutsche, et al.. (2013). Structure. Cited 73 times. https://doi.org/10.1016/j.str.2013.01.018The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.
M. Walter, I. Lucet, O. Patel, et al.. (2007). Journal of molecular biology. Cited 70 times. https://doi.org/10.1016/J.JMB.2007.01.036Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1
J. Elegheert, N. Bracke, P. Pouliot, et al.. (2012). Nature Structural &Molecular Biology. Cited 49 times. https://doi.org/10.1038/nsmb.2367Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles.
J. Elegheert, A. Desfosses, A. Shkumatov, et al.. (2011). Structure. Cited 45 times. https://doi.org/10.1016/j.str.2011.10.012Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
J. Felix, Steven De Munck, K. Verstraete, et al.. (2015). Structure. Cited 39 times. https://doi.org/10.1016/j.str.2015.06.019