Somatic Genome Dynamics of Barrett's Esophagus Patients with Non-Cancer and Cancer Outcomes
Demographics (9)
- AGE_ALIVE - Known Age confirmed alive in cohort study as of April 2019 (phv00420799.v1.p1)
- AGE_BASELINE - Age at baseline endoscopy in cohort study (phv00420790.v1.p1)
- AGE_DEATH - Known Age at death in cohort study as of April 2019 (phv00420798.v1.p1)
- AGE_LAST - Age at last endoscopy in cohort study (phv00420797.v1.p1)
- AGE_T1 - Age at first timepoint TI in case control study (phv00420791.v1.p1)
- AGE_T2 - Age at second timepoint T2 in case control study (phv00420792.v1.p1)
- AGE_T3 - Age at third timepoint T3 (phv00420795.v1.p1)
- PATIENT_AGE_AT_SAMPLING_TIME - Patient age in years at time of sample collection (phv00436009.v1.p1)
- SEX - Self-reported sex (phv00420788.v1.p1)
Disease Events (2)
- AFFECTION_STATUS - Case control status of the subject for nonprogression or progression to esophageal adenocarcinoma outcome (phv00420787.v1.p1)
- AGE_EA_DIAGNOSIS - Age at diagnosis of esophageal adenocarcinoma (EA) (phv00420794.v1.p1)
Race and Ethnicity (1)
- RACE - Self-reported race (phv00420789.v1.p1)
Other (44)
- ANALYTE_TYPE - Analyte type (phv00420831.v1.p1)
- BE_SEGMENT_T1 - Barrett's segment length measured between the ora serrata and the gastroesophageal junction at T1 (phv00420800.v1.p1)
- BE_SEGMENT_T2 - Barrett's segment length measured between the ora serrata and the gastroesophageal junction at T2 (phv00420801.v1.p1)
- BE_SEGMENT_T3 - Barrett's segment length measured between the ora serrata and the gastroesophageal junction at T3 (phv00420802.v1.p1)
- BODY_SITE - Body site where biopsies were collected (phv00420830.v1.p1)
- CM_DISTANCE_FROM_GEJ - Centimeter distance in the esophagus that sample was collected relative to the gastroesophageal junction (phv00436010.v1.p1)
- CONSENT - Consent group as determined by DAC (phv00420781.v1.p1)
- DIAGNOSIS_BASELINE - Maximum histopathologic diagnosis at baseline in cohort study (phv00420803.v1.p1)
- DIAGNOSIS_LAST - Maximum histopathologic diagnosis at last endoscopy in cohort study (phv00420808.v1.p1)
- DIAGNOSIS_MAX_EVER - Maximum histopathologic diagnosis ever in cohort study (phv00420807.v1.p1)
- DIAGNOSIS_T1 - Maximum histopathologic diagnosis at T1 in case control study (phv00420804.v1.p1)
- DIAGNOSIS_T2 - Maximum histopathologic diagnosis at T2 in case control study (phv00420805.v1.p1)
- DIAGNOSIS_T3 - Maximum histopathologic diagnosis at T3 in case control study (phv00420806.v1.p1)
- HISTOLOGICAL_TYPE - Tissue type (phv00420833.v1.p1)
- IS_TUMOR - Tumor status (phv00420832.v1.p1)
- PAIRED_NORMAL - Sample ID of the normal control sample used in paired normal:BE sample analyses (phv00436008.v1.p1)
- SAMPLE_CATEGORY - Sample classification including timepoint (phv00436007.v1.p1)
- SAMPLE_ID - Sample ID (phv00420829.v1.p1)
- SAMPLE_ID - Sample ID (phv00420785.v1.p1)
- SEQUENCING_CENTER - Name of the center that performed the whole genome sequencing (phv00420834.v1.p1)
- SUBJECT_ID - Subject ID (phv00420786.v1.p1)
- SUBJECT_ID - Subject ID (phv00420780.v1.p1)
- SUBJECT_ID - Subject ID (phv00420784.v1.p1)
- T1_GEJ - Distance from incisors to the gastroesophageal junction (GEJ) T1 (phv00420826.v1.p1)
- T1_Max_Mbp_SCA - Maximum load of somatic chromosomal abnormalities (SCA) in Mbp at T1 (phv00420817.v1.p1)
- T1_Max_SV_total - Maximum count of structural variants (SV) at T1 (phv00420819.v1.p1)
- T1_Max_TP53hit - Maximum TP53 abnormality detected at timepoint T1 (phv00420813.v1.p1)
- T1_MaxOftotal_Indel_cnt - Maximum count of indels at timepoint T1 (phv00420811.v1.p1)
- T1_MaxOftotal_SNV_cnt - Maximum count of SNVs at timepoint T1 (phv00420809.v1.p1)
- T1_OS - Distance from incisors to ora serrata (OS) or squamocolumnar junction at T1 (phv00420823.v1.p1)
- T1_WGD - Detection of a whole genome doubled biopsy at timepoint T1 (phv00420815.v1.p1)
- T2_GEJ - Distance from incisors to the gastroesophageal junction (GEJ) T2 (phv00420827.v1.p1)
- T2_Max_Mbp_SCA - Maximum load of somatic chromosomal abnormalities (SCA) in Mbp at T2 (phv00420818.v1.p1)
- T2_Max_SV_total - Maximum count of structural variants (SV) at T2 (phv00420820.v1.p1)
- T2_Max_TP53hit - Maximum TP53 abnormality detected at timepoint T2 (phv00420814.v1.p1)
- T2_MaxOftotal_Indel_cnt - Maximum count of indels at timepoint T2 (phv00420812.v1.p1)
- T2_MaxOftotal_SNV_cnt - Maximum count of SNVs at timepoint T2 (phv00420810.v1.p1)
- T2_OS - Distance from incisors to ora serrata (OS) or squamocolumnar junction at T2 (phv00420824.v1.p1)
- T2_WGD - Detection of a whole genome doubled biopsy at timepoint T2 (phv00420816.v1.p1)
- T3_GEJ - Distance from incisors to the gastroesophageal junction (GEJ) T3 (phv00420828.v1.p1)
- T3_OS - Distance from incisors to ora serrata (OS) or squamocolumnar junction at T3 (phv00420825.v1.p1)
- Unique_ByPatient_Count_SNV+Indel - Count of unique point mutations and indels across all four T1 and T2 biopsies per patient (phv00435990.v1.p1)
- YEARS_T1_T2 - Time between timepoint T1 and T2 (phv00420793.v1.p1)
- YEARS_T1_T3 - Time between timepoint T1 and T3, subset of 10 NP controls with long follow up (phv00420796.v1.p1)