<p>This study was a pilot analysis of samples of human peripheral blood mononuclear cell (PBMCs) from 10 young (23-30 years) and 10 older (68-76 years) healthy Caucasian female volunteers. Whole genome sequencing was performed to assess multiple epigenetic mechanisms and gene expression, including 5hmC-capture sequencing and RNA-sequencing, followed by integrative analyses to identify regions and genes associated with age.</p>

Pilot Sequencing Study of Peripheral Blood Mononuclear Cells in Human    Aging

1 selected publication including "Age-related DNA hydroxymethylation is enriched for gene expression and..." (11 citations)

Pilot Sequencing Study of Peripheral Blood Mononuclear Cells in Human Aging

Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood